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Genomes contain rare guanine-rich sequences capable of assembling into four-stranded helical structures, termed G-quadruplexes, with potential roles in gene regulation and chromosome stability. Their mechanical unfolding has only been…
Graph neural networks (GNNs) aim to learn well-trained representations in a lower-dimension space for downstream tasks while preserving the topological structures. In recent years, attention mechanism, which is brilliant in the fields of…
Computational methods that predict differential gene expression from histone modification signals are highly desirable for understanding how histone modifications control the functional heterogeneity of cells through influencing…
Self-attention is key to the remarkable success of transformers in sequence modeling tasks including many applications in natural language processing and computer vision. Like neural network layers, these attention mechanisms are often…
Gene regulatory relationships can be abstracted as a gene regulatory network (GRN), which plays a key role in characterizing complex cellular processes and pathways. Recently, graph neural networks (GNNs), as a class of deep learning…
Attention mechanisms are widely used to dramatically improve deep learning model performance in various fields. However, their general ability to improve the performance of physiological signal deep learning model is immature. In this…
Inspired by the human cognitive system, attention is a mechanism that imitates the human cognitive awareness about specific information, amplifying critical details to focus more on the essential aspects of data. Deep learning has employed…
Convolutional neural networks have enabled major progresses in addressing pixel-level prediction tasks such as semantic segmentation, depth estimation, surface normal prediction and so on, benefiting from their powerful capabilities in…
Attention is a state of arousal capable of dealing with limited processing bottlenecks in human beings by focusing selectively on one piece of information while ignoring other perceptible information. For decades, concepts and functions of…
In this work, we propose "Residual Attention Network", a convolutional neural network using attention mechanism which can incorporate with state-of-art feed forward network architecture in an end-to-end training fashion. Our Residual…
Although deep neural networks generally have fixed network structures, the concept of dynamic mechanism has drawn more and more attention in recent years. Attention mechanisms compute input-dependent dynamic attention weights for…
Deep neural networks are composed of layers of parametrised linear operations intertwined with non linear activations. In basic models, such as the multi-layer perceptron, a linear layer operates on a simple input vector embedding of the…
Identifying transcription factor binding sites (TFBS) is crucial for understanding gene regulation, as these sites enable transcription factors (TFs) to bind to DNA and modulate gene expression. Despite advances in high-throughput…
In humans, Attention is a core property of all perceptual and cognitive operations. Given our limited ability to process competing sources, attention mechanisms select, modulate, and focus on the information most relevant to behavior. For…
In this work, we aim to predict human eye fixation with view-free scenes based on an end-to-end deep learning architecture. Although Convolutional Neural Networks (CNNs) have made substantial improvement on human attention prediction, it is…
Protein-protein interactions are of great importance in biochemical processes. Accurate prediction of protein-protein interaction sites (PPIs) is crucial for our understanding of biological mechanism. Although numerous approaches have been…
Attention networks have proven to be an effective approach for embedding categorical inference within a deep neural network. However, for many tasks we may want to model richer structural dependencies without abandoning end-to-end training.…
Transformers have been successful in many vision tasks, thanks to their capability of capturing long-range dependency. However, their quadratic computational complexity poses a major obstacle for applying them to vision tasks requiring…
Accurate prediction of binding sites of a given protein, to which ligands can bind, is a critical step in structure-based computational drug discovery. Recently, Equivariant Graph Neural Networks (GNNs) have emerged as a powerful paradigm…
Brain tumor segmentation models have aided diagnosis in recent years. However, they face MRI complexity and variability challenges, including irregular shapes and unclear boundaries, leading to noise, misclassification, and incomplete…