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The rapid growth of medical knowledge and increasing complexity of clinical practice pose challenges. In this context, large language models (LLMs) have demonstrated value; however, inherent limitations remain. Retrieval-augmented…

Large language models (LLMs) have shown impressive potential in helping with numerous medical challenges. Deploying LLMs in high-stakes applications such as medicine, however, brings in many concerns. One major area of concern relates to…

Computation and Language · Computer Science 2025-04-15 Hamed Fayyaz , Raphael Poulain , Rahmatollah Beheshti

Clinical diagnosis requires answers that are accurate, verifiable, and explicitly grounded in official guidelines. While large language models excel at natural language processing, their tendency to hallucinate undermines their utility in…

Artificial Intelligence · Computer Science 2026-05-29 Navapat Nananukul , Mayank Kejriwal

Generative AI models differ from traditional machine learning tools in that they allow users to provide as much or as little information as they choose in their inputs. This flexibility often leads users to omit certain details, relying on…

Computer Science and Game Theory · Computer Science 2026-05-13 Charlotte Park , Kate Donahue , Manish Raghavan

The rise of generative large language models (LLMs) has opened new opportunities for automating knowledge representation through concept maps, a long-standing pedagogical tool valued for fostering meaningful learning and higher-order…

Computers and Society · Computer Science 2025-09-19 Xiaoming Zhai

The recent boom of large language models (LLMs) has re-ignited the hope that artificial intelligence (AI) systems could aid medical diagnosis. Yet despite dazzling benchmark scores, LLM assistants have yet to deliver measurable improvements…

Artificial Intelligence · Computer Science 2025-07-03 Matthew JY Kang , Wenli Yang , Monica R Roberts , Byeong Ho Kang , Charles B Malpas

The recent surge in research focused on generating synthetic data from large language models (LLMs), especially for scenarios with limited data availability, marks a notable shift in Generative Artificial Intelligence (AI). Their ability to…

Machine Learning · Computer Science 2024-03-08 Xu Guo , Yiqiang Chen

Generative AI, the most popular current approach to AI, consists of large language models (LLMs) that are trained to produce outputs that are plausible, but not necessarily correct. Although their abilities are often uncanny, they are…

Machine Learning · Computer Science 2023-08-10 Doug Lenat , Gary Marcus

Clinically acquired brain MRIs and radiology reports are valuable but underutilized resources due to the challenges of manual analysis and data heterogeneity. We developed fine-tuned language models (LMs) to classify brain MRI reports as…

The application of AI in oncology has been limited by its reliance on large, annotated datasets and the need for retraining models for domain-specific diagnostic tasks. Taking heed of these limitations, we investigated in-context learning…

Image and Video Processing · Electrical Eng. & Systems 2025-05-15 Mobina Shrestha , Bishwas Mandal , Vishal Mandal , Asis Shrestha

Generative artificial intelligence (AI) models, such as diffusion models and OpenAI's ChatGPT, are transforming medicine by enhancing diagnostic accuracy and automating clinical workflows. The field has advanced rapidly, evolving from…

Artificial Intelligence · Computer Science 2025-08-28 Lukas Buess , Matthias Keicher , Nassir Navab , Andreas Maier , Soroosh Tayebi Arasteh

Recent advances in Generative AI have transformed how users interact with data analysis through natural language interfaces. However, many systems rely too heavily on LLMs, creating risks of hallucination, opaque reasoning, and reduced user…

Human-Computer Interaction · Computer Science 2025-09-04 Ratanond Koonchanok , Alex Kale , Khairi Reda

Recent advances in vision-language models (VLMs) have achieved remarkable performance on standard medical benchmarks, yet their true clinical reasoning ability remains unclear. Existing datasets predominantly emphasize classification…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Miao Jing , Mengting Jia , Junling Lin , Zhongxia Shen , Huan Gao , Mingkun Xu , Shangyang Li

Large Language Models (LLMs) have emerged as powerful candidates to inform clinical decision-making processes. While these models play an increasingly prominent role in shaping the digital landscape, two growing concerns emerge in…

Computation and Language · Computer Science 2024-04-24 Raphael Poulain , Hamed Fayyaz , Rahmatollah Beheshti

Large Language Model (LLMs) such as ChatGPT that exhibit generative AI capabilities are facing accelerated adoption and innovation. The increased presence of Generative AI (GAI) inevitably raises concerns about the risks and safety…

Computers and Society · Computer Science 2024-07-29 Jaymari Chua , Yun Li , Shiyi Yang , Chen Wang , Lina Yao

Retrieval-augmented generation combined with reinforcement learning has shown promise for grounding large language models in trustworthy medical evidence. However, existing methods rely on exact-match binary rewards, which in clinical…

Artificial Intelligence · Computer Science 2026-05-28 Yuwei Miao , Gen Li , Yunsheng Zeng , Xiandong Li , Yujin Wang , Siyu Chen , Luning Wang , Yunhao Qiao , Junfeng Wang , Jianwei Lv , Bo Yuan

Retrieval-Augmented Large Language Models (LLMs), which integrate external knowledge, have shown remarkable performance in medical domains, including clinical diagnosis. However, existing RAG methods often struggle to tailor retrieval…

Computation and Language · Computer Science 2025-10-16 Jiawei He , Mingyi Jia , Zhihao Jia , Junwen Duan , Yan Song , Jianxin Wang

With recent advances in large language models (LLMs), the concept of automatically generating children's educational materials has become increasingly realistic. Working toward the goal of age-appropriate simplicity in generated educational…

Computation and Language · Computer Science 2023-10-31 Maria Valentini , Jennifer Weber , Jesus Salcido , Téa Wright , Eliana Colunga , Katharina Kann

Large Language Models (LLMs) have shown promising potential in the medical domain, assisting with tasks like clinical note generation and patient communication. However, current LLMs are limited to text-based communication, hindering their…

Computation and Language · Computer Science 2025-06-17 Yusheng Liao , Shuyang Jiang , Yanfeng Wang , Yu Wang

Cutaneous malignancies demand early detection for favorable outcomes, yet current diagnostics suffer from inter-observer variability and access disparities. While AI shows promise, existing dermatological systems are limited by homogeneous…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Sher Khan , Raz Muhammad , Adil Hussain , Muhammad Sajjad , Muhammad Rashid