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Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

Large Language Models (LLMs) like GPT-4, MedPaLM-2, and Med-Gemini achieve performance competitively with human experts across various medical benchmarks. However, they still face challenges in making professional diagnoses akin to…

Computation and Language · Computer Science 2024-08-23 Xiaohan Wang , Xiaoyan Yang , Yuqi Zhu , Yue Shen , Jian Wang , Peng Wei , Lei Liang , Jinjie Gu , Huajun Chen , Ningyu Zhang

Specialized clinical AI assistants are rapidly entering medical practice, often framed as safer or more reliable than general-purpose large language models (LLMs). Yet, unlike frontier models, these clinical tools are rarely subjected to…

Computation and Language · Computer Science 2025-12-02 Krithik Vishwanath , Mrigayu Ghosh , Anton Alyakin , Daniel Alexander Alber , Yindalon Aphinyanaphongs , Eric Karl Oermann

Clinical decision making (CDM) is a complex, dynamic process crucial to healthcare delivery, yet it remains a significant challenge for artificial intelligence systems. While Large Language Model (LLM)-based agents have been tested on…

Computation and Language · Computer Science 2025-10-13 Jie Liu , Wenxuan Wang , Zizhan Ma , Guolin Huang , Yihang SU , Kao-Jung Chang , Wenting Chen , Haoliang Li , Linlin Shen , Michael Lyu

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Computation and Language · Computer Science 2025-07-10 Garapati Keerthana , Manik Gupta

Large Language Models (LLMs) are increasingly deployed in medicine. However, their utility in non-generative clinical prediction, often presumed inferior to specialized models, remains under-evaluated, leading to ongoing debate within the…

Social problems stemming from the shortage of radiologists are intensifying, and artificial intelligence is being highlighted as a potential solution. Recently emerging large-scale generative AI has expanded from large language models…

Computer Vision and Pattern Recognition · Computer Science 2024-09-23 Inwoo Seo , Eunkyoung Bae , Joo-Young Jeon , Young-Sang Yoon , Jiho Cha

The rapid rise in popularity of Large Language Models (LLMs) with emerging capabilities has spurred public curiosity to evaluate and compare different LLMs, leading many researchers to propose their own LLM benchmarks. Noticing preliminary…

Artificial Intelligence · Computer Science 2025-05-15 Timothy R. McIntosh , Teo Susnjak , Nalin Arachchilage , Tong Liu , Paul Watters , Malka N. Halgamuge

How does the progressive embracement of Large Language Models (LLMs) affect scientific peer reviewing? This multifaceted question is fundamental to the effectiveness -- as well as to the integrity -- of the scientific process. Recent…

Machine Learning · Computer Science 2025-10-27 Luca Demetrio , Giovanni Apruzzese , Kathrin Grosse , Pavel Laskov , Emil Lupu , Vera Rimmer , Philine Widmer

Generative AI models, including large language models (LLMs) and vision-language models (VLMs), are increasingly used to interpret medical images and answer clinical questions. Their responses often include inaccuracies; therefore, safety…

Computation and Language · Computer Science 2025-07-14 Sonali Sharma , Ahmed M. Alaa , Roxana Daneshjou

Generative AI technologies, particularly Large Language Models (LLMs), have transformed information management systems but introduced substantial biases that can compromise their effectiveness in informing business decision-making. This…

Computers and Society · Computer Science 2025-02-18 Xiahua Wei , Naveen Kumar , Han Zhang

Variant and gene interpretation are fundamental to personalized medicine and translational biomedicine. However, traditional approaches are manual and labor-intensive. Generative language models (LMs) can facilitate this process,…

Artificial Intelligence · Computer Science 2025-10-15 Owen Queen , Harrison G. Zhang , James Zou

The advent of generative artificial intelligence, especially large language models (LLMs), presents opportunities for innovation in research, clinical practice, and education. Recently, Dihan et al. lauded LLM tool NotebookLM's potential,…

Artificial Intelligence · Computer Science 2025-05-06 Max Reuter , Maura Philippone , Bond Benton , Laura Dilley

Recent advancements in Large Language Models (LLMs) have demonstrated significant promise in clinical diagnosis. However, current models struggle to emulate the iterative, diagnostic hypothesis-driven reasoning of real clinical scenarios.…

Computation and Language · Computer Science 2026-01-06 Qipeng Wang , Rui Sheng , Yafei Li , Huamin Qu , Yushi Sun , Min Zhu

The rise of Generative AI (GAI) and Large Language Models (LLMs) has transformed industrial landscapes, offering unprecedented opportunities for efficiency and innovation while raising critical ethical, regulatory, and operational…

Computers and Society · Computer Science 2026-03-11 Junfeng Jiao , Saleh Afroogh , Kevin Chen , David Atkinson , Amit Dhurandhar

Generative medical AI now appears fluent and knowledgeable enough to resemble clinical intelligence, encouraging the belief that scaling will make it safe. But clinical reasoning is not text generation. It is a responsibility-bound process…

Artificial Intelligence · Computer Science 2026-02-02 Vaibhav Ram S. V. N. S , Swetanshu Agrawal , Samudra Banerjee , Abdul Muhsin

AI in dermatology is evolving at a rapid pace but the major limitation to training trustworthy classifiers is the scarcity of data with ground-truth concept level labels, which are meta-labels semantically meaningful to humans. Foundation…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Soham Gadgil , Mahtab Bigverdi

Large language models (LLMs) have shown remarkable capabilities in various natural language tasks and are increasingly being applied in healthcare domains. This work demonstrates a new LLM-powered disease risk assessment approach via…

Computation and Language · Computer Science 2024-09-24 Mohammad Amin Roshani , Xiangyu Zhou , Yao Qiang , Srinivasan Suresh , Steve Hicks , Usha Sethuraman , Dongxiao Zhu

Generative Artificial Intelligence (GenAI) is taking the world by storm. It promises transformative opportunities for advancing and disrupting existing practices, including healthcare. From large language models (LLMs) for clinical note…

Artificial Intelligence · Computer Science 2025-10-29 Gang Chen , Changshuo Liu , Gene Anne Ooi , Marcus Tan , Zhongle Xie , Jianwei Yin , James Wei Luen Yip , Wenqiao Zhang , Jiaqi Zhu , Beng Chin Ooi

Accurate symptom-to-disease classification and clinically grounded treatment recommendations remain challenging, particularly in heterogeneous patient settings with high diagnostic risk. Existing large language model (LLM)-based systems…