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Accurate pose estimation and shift correction are key challenges in cryo-EM due to the very low SNR, which directly impacts the fidelity of 3D reconstructions. We present an approach for pose estimation in cryo-EM that leverages…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Kaishva Chintan Shah , Virajith Boddapati , Karthik S. Gurumoorthy , Sandip Kaledhonkar , Ajit Rajwade

Cryo-electron tomography (cryo-ET) has emerged as a powerful tool for studying the structural heterogeneity of proteins and their complexes, offering insights into macromolecular dynamics directly within cells. Driven by recent…

Biomolecules · Quantitative Biology 2025-07-01 Jackson Carrion , Joseph H. Davis

Regularization methods using prior knowledge are essential in solving ill-posed inverse problems such as Electrical Impedance Tomography (EIT). However, designing effective regularization and integrating prior information into EIT remains…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Dong Liu , Yuanchao Wu , Bowen Tong , Jiansong Deng

Cryogenic electron microscopy (Cryo-EM) has become an essential tool for capturing high-resolution biological structures. Despite its advantage in visualizations, the large storage size of Cryo-EM data file poses significant challenges for…

Machine Learning · Computer Science 2025-12-16 Chunyu Zou

State estimation in complex illumination environments based on conventional visual-inertial odometry is a challenging task due to the severe visual degradation of the visual camera. The thermal infrared camera is capable of all-day time and…

Robotics · Computer Science 2022-10-25 Yu Wang , Haoyao Chen , Yufeng Liu , Shiwu Zhang

Computed Tomography (CT) with its remarkable capability for three-dimensional imaging from multiple projections, enjoys a broad range of applications in clinical diagnosis, scientific observation, and industrial detection. Neural Adaptive…

Image and Video Processing · Electrical Eng. & Systems 2023-11-06 Bo Xiong , Changqing Su , Zihan Lin , You Zhou , Zhaofei Yu

We propose and investigate an "interface-flattening" transformation, hinging upon Transformation Optics (T.O.) techniques, to facilitate the rigorous analysis of electromagnetic (EM) fields radiated by sources embedded in tilted,…

Computational Physics · Physics 2016-02-17 Kamalesh Sainath , Fernando L. Teixeira

Electrical impedance tomography is an imaging modality for extracting information on the conductivity distribution inside a physical body from boundary measurements of current and voltage. In many practical applications, it is a priori…

Numerical Analysis · Mathematics 2014-06-06 Lauri Harhanen , Nuutti Hyvönen , Helle Majander , Stratos Staboulis

Cryo-electron microscopy (cryo-EM) is an indispensable technique for determining the 3D structures of dynamic biomolecular complexes. While typically applied to image a single molecular species, cryo-EM has the potential for structure…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Jeffrey Gu , Minkyu Jeon , Ambri Ma , Serena Yeung-Levy , Ellen D. Zhong

In recent years, deep learning-based image compression, particularly through generative models, has emerged as a pivotal area of research. Despite significant advancements, challenges such as diminished sharpness and quality in…

Image and Video Processing · Electrical Eng. & Systems 2024-09-18 Ryugo Morita , Hitoshi Nishimura , Ko Watanabe , Andreas Dengel , Jinjia Zhou

Low Dose Computed Tomography suffers from a high amount of noise and/or undersampling artefacts in the reconstructed image. In the current article, a Deep Learning technique is exploited as a regularization term for the iterative…

Image and Video Processing · Electrical Eng. & Systems 2019-06-04 Shabab Bazrafkan , Vincent Van Nieuwenhove , Joris Soons , Jan De Beenhouwer , Jan Sijbers

This paper presents a multi-resolution reconstruction method for Electrical Impedance Tomography (EIT), referred to as MR-EIT, which is capable of operating in both supervised and unsupervised learning modes. MR-EIT integrates an ordered…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Fangming Shi , Jinzhen Liu , Xiangqian Meng , Yapeng Zhou , Hui Xiong

Cryo-electron tomography (Cryo-ET) is a 3D imaging technique that enables the systemic study of shape, abundance, and distribution of macromolecular structures in single cells in near-atomic resolution. However, the systematic and efficient…

Biomolecules · Quantitative Biology 2021-06-29 Kai Yi , Jianye Pang , Yungeng Zhang , Xiangrui Zeng , Min Xu

Distribution-to-Distribution (D2D) point cloud registration algorithms are fast, interpretable, and perform well in unstructured environments. Unfortunately, existing strategies for predicting solution error for these methods are overly…

Robotics · Computer Science 2024-10-02 Matthew McDermott , Jason Rife

Electrical Impedance Tomography (EIT) systems are becoming popular because they present several advantages over competing systems. However, EIT leads to images with very low resolution. Moreover, the nonuniform sampling characteristic of…

Computer Vision and Pattern Recognition · Computer Science 2019-05-01 Ricardo A. Borsoi , Julio C. C. Aya , Guilherme H. Costa , José C. M. Bermudez

Time-resolved high-resolution X-ray Computed Tomography (4D $\mu$CT) is an imaging technique that offers insight into the evolution of dynamic processes inside materials that are opaque to visible light. Conventional tomographic…

Image and Video Processing · Electrical Eng. & Systems 2026-01-12 Wannes Goethals , Tom Bultreys , Steffen Berg , Matthieu N. Boone , Jan Aelterman

Computed Tomography (CT) reconstruction is a fundamental component to a wide variety of applications ranging from security, to healthcare. The classical techniques require measuring projections, called sinograms, from a full 180$^\circ$…

Computer Vision and Pattern Recognition · Computer Science 2018-07-12 Rushil Anirudh , Hyojin Kim , Jayaraman J. Thiagarajan , K. Aditya Mohan , Kyle Champley , Timo Bremer

Thermal infrared imaging exhibits considerable potentials for robotic perception tasks, especially in environments with poor visibility or challenging lighting conditions. However, TIR images typically suffer from heavy non-uniform…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Tai Hyoung Rhee , Dong-guw Lee , Ayoung Kim

In single-particle cryo-electron microscopy (cryo-EM), the efficient determination of orientation parameters for 2D projection images poses a significant challenge yet is crucial for reconstructing 3D structures. This task is complicated by…

Image and Video Processing · Electrical Eng. & Systems 2025-09-30 Szu-Chi Chung

Electrical Impedance Tomography (EIT) is a promising noninvasive imaging technique that reconstructs the spatial conductivity distribution from boundary voltage measurements. However, it poses a highly nonlinear and ill-posed inverse…

Signal Processing · Electrical Eng. & Systems 2025-12-16 Xuanxuan Yang , Yangming Zhang , Haofeng Chen , Gang Ma , Xiaojie Wang