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In this paper, we propose a deep learning approach for image registration by predicting deformation from image appearance. Since obtaining ground-truth deformation fields for training can be challenging, we design a fully convolutional…

Computer Vision and Pattern Recognition · Computer Science 2018-02-14 Jingfan Fan , Xiaohuan Cao , Pew-Thian Yap , Dinggang Shen

We propose a registration algorithm for 2D CT/MRI medical images with a new unsupervised end-to-end strategy using convolutional neural networks. The contributions of our algorithm are threefold: (1) We transplant traditional image…

Computer Vision and Pattern Recognition · Computer Science 2018-01-23 Siyuan Shan , Wen Yan , Xiaoqing Guo , Eric I-Chao Chang , Yubo Fan , Yan Xu

Sharpness-Aware Minimization (SAM) has attracted considerable attention for its effectiveness in improving generalization in deep neural network training by explicitly minimizing sharpness in the loss landscape. Its success, however, relies…

Machine Learning · Computer Science 2025-06-16 Sungbin Shin , Dongyeop Lee , Maksym Andriushchenko , Namhoon Lee

Image registration is fundamental in medical imaging, enabling precise alignment of anatomical structures for diagnosis, treatment planning, image-guided interventions, and longitudinal monitoring. This work introduces IMPACT (Image Metric…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Valentin Boussot , Cédric Hémon , Jean-Claude Nunes , Jason Dowling , Simon Rouzé , Caroline Lafond , Anaïs Barateau , Jean-Louis Dillenseger

Medical image registration is a challenging task involving the estimation of spatial transformations to establish anatomical correspondence between pairs or groups of images. Recently, deep learning-based image registration methods have…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Xiang Chen , Yan Xia , Nishant Ravikumar , Alejandro F Frangi

Image normalization is a building block in medical image analysis. Conventional approaches are customarily utilized on a per-dataset basis. This strategy, however, prevents the current normalization algorithms from fully exploiting the…

Machine Learning · Computer Science 2020-10-06 Pierre-Luc Delisle , Benoit Anctil-Robitaille , Christian Desrosiers , Herve Lombaert

In dynamic MRI, sufficient time resolution can often only be obtained using imaging protocols which produce undersampled data for each image in the time series. This has led to the popularity of compressed sensing (CS) based image…

Multimodal image registration is a fundamental task and a prerequisite for downstream cross-modal analysis. Despite recent progress in shared feature extraction and multi-scale architectures, two key limitations remain. First, some methods…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Chunlei Zhang , Jiahao Xia , Yun Xiao , Bo Jiang , Jian Zhang

This work proposes a multimodal diffeomorphic registration method using Neural Ordinary Differential Equations (Neural ODEs). Nonrigid registration algorithms exhibit tradeoffs between their accuracy, the computational complexity of their…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Salvador Rodriguez-Sanz , Monica Hernandez

The choice of making an intervention depends on its potential benefit or harm in comparison to alternatives. Estimating the likely outcome of alternatives from observational data is a challenging problem as all outcomes are never observed,…

Machine Learning · Statistics 2020-02-18 Yao Zhang , Alexis Bellot , Mihaela van der Schaar

The deep image prior showed that a randomly initialized network with a suitable architecture can be trained to solve inverse imaging problems by simply optimizing it's parameters to reconstruct a single degraded image. However, it suffers…

Image and Video Processing · Electrical Eng. & Systems 2022-01-03 Zenglin Shi , Pascal Mettes , Subhransu Maji , Cees G. M. Snoek

The nonrigid alignment between a pre-operative biomechanical model and an intra-operative observation is a critical step to track the motion of a soft organ in augmented surgery. While many elastic registration procedures introduce…

Optimization and Control · Mathematics 2022-06-23 Guillaume Mestdagh , Stéphane Cotin

The ability to estimate the perceptual error between images is an important problem in computer vision with many applications. Although it has been studied extensively, however, no method currently exists that can robustly predict visual…

Computer Vision and Pattern Recognition · Computer Science 2018-06-07 Ekta Prashnani , Hong Cai , Yasamin Mostofi , Pradeep Sen

Over-parameterized neural network models often lead to significant performance discrepancies between training and test sets, a phenomenon known as overfitting. To address this, researchers have proposed numerous regularization techniques…

Machine Learning · Computer Science 2025-01-27 RuiZhe Jiang , Haotian Lei

Deep learning technologies have dramatically reshaped the field of medical image registration over the past decade. The initial developments, such as regression-based and U-Net-based networks, established the foundation for deep learning in…

Image and Video Processing · Electrical Eng. & Systems 2024-11-04 Junyu Chen , Yihao Liu , Shuwen Wei , Zhangxing Bian , Shalini Subramanian , Aaron Carass , Jerry L. Prince , Yong Du

In recent literature there are plenty of works that combine handcrafted and learnable regularizers to solve inverse imaging problems. While this hybrid approach has demonstrated promising results, the motivation for combining handcrafted…

Computer Vision and Pattern Recognition · Computer Science 2025-05-23 Alexandros Gkillas , Dimitris Ampeliotis , Kostas Berberidis

This work considers semi-supervised segmentation as a dense prediction problem based on prototype vector correlation and proposes a simple way to represent each segmentation class with multiple prototypes. To avoid degenerate solutions, two…

Computer Vision and Pattern Recognition · Computer Science 2021-11-17 Jizong Peng , Christian Desrosiers , Marco Pedersoli

Image registration is a fundamental step in medical image analysis. Ideally, the transformation that registers one image to another should be a diffeomorphism that is both invertible and smooth. Traditional methods like geodesic shooting…

Computer Vision and Pattern Recognition · Computer Science 2019-07-02 Dongyang Kuang

The strength of machine learning models stems from their ability to learn complex function approximations from data; however, this strength also makes training deep neural networks challenging. Notably, the complex models tend to memorize…

Computer Vision and Pattern Recognition · Computer Science 2023-04-17 Mofassir ul Islam Arif , Mohsan Jameel , Josif Grabocka , Lars Schmidt-Thieme

Regularization is a fundamental technique to prevent over-fitting and to improve generalization performances by constraining a model's complexity. Current Deep Networks heavily rely on regularizers such as Data-Augmentation (DA) or…

Machine Learning · Computer Science 2022-04-12 Randall Balestriero , Leon Bottou , Yann LeCun