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Recent advancements in biology and chemistry have leveraged multi-modal learning, integrating molecules and their natural language descriptions to enhance drug discovery. However, current pre-training frameworks are limited to two…

Machine Learning · Computer Science 2025-02-05 Teng Xiao , Chao Cui , Huaisheng Zhu , Vasant G. Honavar

In recent years, large language models (LLMs) have driven major advances in language understanding, marking a significant step toward artificial general intelligence (AGI). With increasing demands for higher-level semantics and cross-modal…

Computation and Language · Computer Science 2025-09-30 Yuntao Shou , Tao Meng , Wei Ai , Keqin Li

As the frontiers of biology become increasingly interdisciplinary, the physics education community has engaged in ongoing efforts to make physics classes more relevant to life sciences majors. These efforts are complicated by the many…

Advancements in Natural Language Processing have enabled specialized language models, but integrating domain-specific knowledge into general-purpose models in multilingual settings remains challenging, particularly for technical vocabulary.…

Computation and Language · Computer Science 2025-03-13 Thibault Rousset , Taisei Kakibuchi , Yusuke Sasaki , Yoshihide Nomura

Representing the semantics of words is a long-standing problem for the natural language processing community. Most methods compute word semantics given their textual context in large corpora. More recently, researchers attempted to…

Computation and Language · Computer Science 2017-11-10 Éloi Zablocki , Benjamin Piwowarski , Laure Soulier , Patrick Gallinari

Recently, machine learning (ML) has established itself in various worldwide benchmarking competitions in computational biology, including Critical Assessment of Structure Prediction (CASP) and Drug Design Data Resource (D3R) Grand…

Biomolecules · Quantitative Biology 2020-04-22 Duc D Nguyen , Zixuan Cang , Guo-Wei Wei

Recent advances in artificial intelligence, particularly large language models LLMs, have shown promising capabilities in transforming rare disease research. This survey paper explores the integration of LLMs in the analysis of rare…

Computation and Language · Computer Science 2025-05-26 Valentina Carbonari , Pierangelo Veltri , Pietro Hiram Guzzi

The rise of Multimodal Large Language Models (MLLMs) has become a transformative force in the field of artificial intelligence, enabling machines to process and generate content across multiple modalities, such as text, images, audio, and…

Computation and Language · Computer Science 2025-12-09 Ming Li , Keyu Chen , Ziqian Bi , Ming Liu , Xinyuan Song , Zekun Jiang , Tianyang Wang , Benji Peng , Qian Niu , Junyu Liu , Jinlang Wang , Sen Zhang , Xuanhe Pan , Jiawei Xu , Pohsun Feng

Multi-omics studies often rely on pathway enrichment to interpret heterogeneous molecular changes, but pathway enrichment (PE)-based workflows inherit structural limitations of pathway resources, including curation lag, functional…

Computation and Language · Computer Science 2026-01-01 Sibo Wei , Peng Chen , Lifeng Dong , Yin Luo , Lei Wang , Peng Zhang , Wenpeng Lu , Jianbin Guo , Hongjun Yang , Dajun Zeng

Multimodal search has become increasingly important in providing users with a natural and effective way to ex-press their search intentions. Images offer fine-grained details of the desired products, while text allows for easily…

Computer Vision and Pattern Recognition · Computer Science 2024-04-25 Oriol Barbany , Michael Huang , Xinliang Zhu , Arnab Dhua

For the complex human brain that enables us to communicate in natural language, we gathered good understandings of principles underlying language acquisition and processing, knowledge about socio-cultural conditions, and insights about…

Computation and Language · Computer Science 2018-02-08 Stefan Heinrich , Stefan Wermter

The impact of Transformer-based language models has been unprecedented in Natural Language Processing (NLP). The success of such models has also led to their adoption in other fields including bioinformatics. Taking this into account, this…

Machine Learning · Computer Science 2025-07-21 Nimisha Ghosh , Daniele Santoni , Debaleena Nawn , Eleonora Ottaviani , Giovanni Felici

Molecular property prediction has gained significant attention due to its transformative potential in multiple scientific disciplines. Conventionally, a molecule graph can be represented either as a graph-structured data or a SMILES text.…

Machine Learning · Computer Science 2023-07-17 Chen Qian , Huayi Tang , Zhirui Yang , Hong Liang , Yong Liu

We explore the integration of large language models (LLMs) into visual analytics (VA) systems to transform their capabilities through intuitive natural language interactions. We survey current research directions in this emerging field,…

Human-Computer Interaction · Computer Science 2025-07-01 Maeve Hutchinson , Radu Jianu , Aidan Slingsby , Pranava Madhyastha

Molecular property prediction is a crucial foundation for drug discovery. In recent years, pre-trained deep learning models have been widely applied to this task. Some approaches that incorporate prior biological domain knowledge into the…

Machine Learning · Computer Science 2024-08-20 Tianyu Zhang , Yuxiang Ren , Chengbin Hou , Hairong Lv , Xuegong Zhang

Language modeling studies the probability distributions over strings of texts. It is one of the most fundamental tasks in natural language processing (NLP). It has been widely used in text generation, speech recognition, machine…

Computation and Language · Computer Science 2024-07-18 Chengwei Wei , Yun-Cheng Wang , Bin Wang , C. -C. Jay Kuo

Elucidating the language-brain relationship requires bridging the methodological gap between the abstract theoretical frameworks of linguistics and the empirical neural data of neuroscience. Serving as an interdisciplinary cornerstone,…

Neurons and Cognition · Quantitative Biology 2026-02-16 Fudong Zhang , Bo Chai , Yujie Wu , Wai Ting Siok , Nizhuan Wang

Large Language Models (LLMs) have achieved remarkable success in Natural Language Processing (NLP), yet their cross-lingual performance consistency remains a significant challenge. This paper introduces a novel methodology for efficiently…

Computation and Language · Computer Science 2025-05-27 Zixiang Xu , Yanbo Wang , Yue Huang , Xiuying Chen , Jieyu Zhao , Meng Jiang , Xiangliang Zhang

There is increasing adoption of artificial intelligence in drug discovery. However, existing studies use machine learning to mainly utilize the chemical structures of molecules but ignore the vast textual knowledge available in chemistry.…

Machine Learning · Computer Science 2024-01-31 Shengchao Liu , Weili Nie , Chengpeng Wang , Jiarui Lu , Zhuoran Qiao , Ling Liu , Jian Tang , Chaowei Xiao , Anima Anandkumar

Unlike traditional vision-only models, vision language models (VLMs) offer an intuitive way to access visual content through language prompting by combining a large language model (LLM) with a vision encoder. However, both the LLM and the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Paul Gavrikov , Jovita Lukasik , Steffen Jung , Robert Geirhos , M. Jehanzeb Mirza , Margret Keuper , Janis Keuper