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Large Language Models (LLMs) have significant impact on the healthcare scenarios but remain prohibitively large for deployment in real-time, resource-constrained environments such as edge devices. In this work, we introduce a novel medical…

Computation and Language · Computer Science 2025-08-08 Uttej Kallakurik , Edward Humes , Rithvik Jonna , Xiaomin Lin , Tinoosh Mohsenin

Continual pre-training has increasingly become the predominant approach for adapting Large Language Models (LLMs) to new domains. This process involves updating the pre-trained LLM with a corpus from a new domain, resulting in a shift in…

Computation and Language · Computer Science 2024-06-28 Yiduo Guo , Jie Fu , Huishuai Zhang , Dongyan Zhao , Yikang Shen

Large language models (LLMs) demonstrate remarkable medical expertise, but data privacy concerns impede their direct use in healthcare environments. Although offering improved data privacy protection, domain-specific small language models…

Computation and Language · Computer Science 2024-05-17 Xinlu Zhang , Shiyang Li , Xianjun Yang , Chenxin Tian , Yao Qin , Linda Ruth Petzold

As specialized large language models (LLMs) become increasingly prevalent, model merging methods are being used to combine them to create a single multi-task model without requiring any additional data or training. However, these approaches…

Machine Learning · Computer Science 2025-03-11 Hetarth Chopra , Vidhi Rambhia , Vikram Adve

Large Language Models (LLMs), particularly those similar to ChatGPT, have significantly influenced the field of Natural Language Processing (NLP). While these models excel in general language tasks, their performance in domain-specific…

Computation and Language · Computer Science 2024-01-02 Omid Rohanian , Mohammadmahdi Nouriborji , David A. Clifton

Recent advancements in Contrastive Language-Image Pre-training (CLIP) have demonstrated notable success in self-supervised representation learning across various tasks. However, the existing CLIP-like approaches often demand extensive GPU…

Computer Vision and Pattern Recognition · Computer Science 2024-07-31 Yuexi Du , Brian Chang , Nicha C. Dvornek

Post-training compression of large language models (LLMs) often relies on low-rank weight approximations that represent each column of the weight matrix in a shared low-dimensional subspace. This strategy is computationally efficient but…

Computation and Language · Computer Science 2026-05-05 Denis Makhov , Dmitriy Shopkhoev , Magauiya Zhussip , Ammar Ali , Stamatios Lefkimmiatis

Large language models have demonstrated remarkable capabilities across various tasks, primarily attributed to the utilization of diversely sourced data. However, the impact of pretraining data composition on model performance remains poorly…

Machine Learning · Computer Science 2025-01-28 Ce Ge , Zhijian Ma , Daoyuan Chen , Yaliang Li , Bolin Ding

The lack of large annotated datasets in medical imaging is an intrinsic burden for supervised Deep Learning (DL) segmentation models. Few-shot learning approaches are cost-effective solutions to transfer pre-trained models using only…

Image and Video Processing · Electrical Eng. & Systems 2024-09-05 Ali Keshavarzi , Elsa Angelini

Large language models deliver strong generative performance but at the cost of massive parameter counts, memory use, and decoding latency. Prior work has shown that pruning and structured sparsity can preserve accuracy under substantial…

Computation and Language · Computer Science 2026-04-17 Andrew Kiruluta

Training large language models (LLMs) from scratch requires significant computational resources, driving interest in developing smaller, domain-specific LLMs that maintain both efficiency and strong task performance. Medium-sized models…

Computation and Language · Computer Science 2026-03-02 Chaitali Bhattacharyya , Hyunsei Lee , Junyoung Lee , Shinhyoung Jang , Il hong Suh , Yeseong Kim

In many-task optimization scenarios, surrogate models are valuable for mitigating the computational burden of repeated fitness evaluations across tasks. This study proposes a novel meta-surrogate framework to assist many-task optimization,…

Machine Learning · Computer Science 2026-02-05 Xian-Rong Zhang , Yue-Jiao Gong , Yuan-Ting Zhong , Ting Huang , Jun Zhang

Large Language Models (LLMs) are expected to significantly contribute to patient care, diagnostics, and administrative processes. Emerging biomedical LLMs aim to address healthcare-specific challenges, including privacy demands and…

Computation and Language · Computer Science 2025-10-14 Amin Dada , Marie Bauer , Amanda Butler Contreras , Osman Alperen Koraş , Constantin Marc Seibold , Kaleb E Smith , Jens Kleesiek

Large language models (LLMs) have achieved significant progress across various domains, but their increasing scale results in high computational and memory costs. Recent studies have revealed that LLMs exhibit sparsity, providing the…

Machine Learning · Computer Science 2025-07-01 Mingkuan Feng , Jinyang Wu , Shuai Zhang , Pengpeng Shao , Ruihan Jin , Zhengqi Wen , Jianhua Tao , Feihu Che

Supervised fine-tuning (SFT) is a standard approach to adapting large language models (LLMs) to new domains. In this work, we improve the statistical efficiency of SFT by selecting an informative subset of training examples. Specifically,…

Machine Learning · Computer Science 2025-05-22 Rohan Deb , Kiran Thekumparampil , Kousha Kalantari , Gaurush Hiranandani , Shoham Sabach , Branislav Kveton

Large language models (LLMs) are increasingly adapted into domain-specific variants for applications in law, healthcare, and finance. Their scale, however, limits deployment in resource-constrained settings, and existing compression…

Machine Learning · Computer Science 2026-01-23 Songlin Zhao , Michael Pitts , Zhuwei Qin

Language models pre-trained on biomedical corpora, such as BioBERT, have recently shown promising results on downstream biomedical tasks. Many existing pre-trained models, on the other hand, are resource-intensive and computationally heavy…

Computation and Language · Computer Science 2022-09-08 Omid Rohanian , Mohammadmahdi Nouriborji , Samaneh Kouchaki , David A. Clifton

Pre-trained language models (PLMs) are engineered to be robust in contextual understanding and exhibit outstanding performance in various natural language processing tasks. However, their considerable size incurs significant computational…

Computation and Language · Computer Science 2024-08-21 Guanchen Li , Xiandong Zhao , Lian Liu , Zeping Li , Dong Li , Lu Tian , Jie He , Ashish Sirasao , Emad Barsoum

The training of large language models (LLMs) is expensive. In this paper, we study data-efficient approaches for pre-training LLMs, i.e., techniques that aim to optimize the Pareto frontier of model quality and training resource/data…

Large language models are powerful but costly. We ask whether meta-learning can make the pretraining of small language models not only better but also more interpretable. We integrate first-order MAML with subset-masked LM pretraining,…

Computation and Language · Computer Science 2025-11-10 David Demitri Africa , Yuval Weiss , Paula Buttery , Richard Diehl Martinez