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The pre-training and fine-tuning paradigm has contributed to a number of breakthroughs in Natural Language Processing (NLP). Instead of directly training on a downstream task, language models are first pre-trained on large datasets with…

Machine Learning · Computer Science 2023-08-01 Vithursan Thangarasa , Abhay Gupta , William Marshall , Tianda Li , Kevin Leong , Dennis DeCoste , Sean Lie , Shreyas Saxena

Large language models (LLMs) have demonstrated proficiency across various natural language processing (NLP) tasks but often require additional training, such as continual pre-training and supervised fine-tuning. However, the costs…

Computation and Language · Computer Science 2024-06-07 Da Ma , Lu Chen , Pengyu Wang , Hongshen Xu , Hanqi Li , Liangtai Sun , Su Zhu , Shuai Fan , Kai Yu

Large language models (LLMs) have revolutionized Natural Language Processing (NLP), but their size creates computational bottlenecks. We introduce a novel approach to create accurate, sparse foundational versions of performant LLMs that…

Pre-trained Large Language Models (LLMs) often struggle on out-of-domain datasets like healthcare focused text. We explore specialized pre-training to adapt smaller LLMs to different healthcare datasets. Three methods are assessed:…

Computation and Language · Computer Science 2024-04-01 Niall Taylor , Dan Schofield , Andrey Kormilitzin , Dan W Joyce , Alejo Nevado-Holgado

Large language models (LLMs) offer a scalable mechanism to elicit domain-informed prior information for high-dimensional variable selection. However, existing methods such as LLM-Lasso are sensitive to weight quality, with performance…

Machine Learning · Statistics 2026-05-25 Caleb Skinner , Yihan Guo , Meng Li

Recent development in Large Language Models (LLMs) and Multi-modal Large Language Models (MLLMs) have leverage Attention-based Transformer architectures and achieved superior performance and generalization capabilities. They have since…

Computation and Language · Computer Science 2025-05-20 Yuze Zhao , Jintao Huang , Jinghan Hu , Xingjun Wang , Yunlin Mao , Daoze Zhang , Hong Zhang , Zeyinzi Jiang , Zhikai Wu , Baole Ai , Ang Wang , Wenmeng Zhou , Yingda Chen

While large language models (LLMs) have achieved remarkable performance across a wide range of tasks, their massive scale incurs prohibitive computational and memory costs for pre-training from scratch. Recent studies have investigated the…

Machine Learning · Computer Science 2025-08-05 Jiaxi Li , Lu Yin , Li Shen , Jinjin Xu , Liwu Xu , Tianjin Huang , Wenwu Wang , Shiwei Liu , Xilu Wang

The remarkable success of Large Language Models (LLMs) relies heavily on their substantial scale, which poses significant challenges during model deployment in terms of latency and memory consumption. Recently, numerous studies have…

Computation and Language · Computer Science 2024-12-19 Weiyu Huang , Yuezhou Hu , Guohao Jian , Jun Zhu , Jianfei Chen

A salient characteristic of pre-trained language models (PTLMs) is a remarkable improvement in their generalization capability and emergence of new capabilities with increasing model capacity and pre-training dataset size. Consequently, we…

Large Language Models (LLMs) offer strong capabilities but incur high inference costs due to dense computation and memory access. Training-free activation sparsity is a promising approach for efficient LLM inference, yet existing methods…

Machine Learning · Computer Science 2026-02-17 Lei Chen , Yuan Meng , Xiaoyu Zhan , Zhi Wang , Wenwu Zhu

A primary challenge in large language model (LLM) development is their onerous pre-training cost. Typically, such pre-training involves optimizing a self-supervised objective (such as next-token prediction) over a large corpus. This paper…

Modern large-scale Pre-trained Language Models (PLMs) have achieved tremendous success on a wide range of downstream tasks. However, most of the LM pre-training objectives only focus on text reconstruction, but have not sought to learn…

Computation and Language · Computer Science 2022-10-28 Liliang Ren , Zixuan Zhang , Han Wang , Clare R. Voss , Chengxiang Zhai , Heng Ji

Open-source, multilingual medical large language models (LLMs) have the potential to serve linguistically diverse populations across different regions. Adapting generic LLMs for healthcare often requires continual pretraining, but this…

Computation and Language · Computer Science 2024-09-10 Meng Zhou , Surajsinh Parmar , Anubhav Bhatti

Recently, Large Language Models (LLM) have demonstrated impressive capability to solve a wide range of tasks. However, despite their success across various tasks, no prior work has investigated their capability in the biomedical domain yet.…

Computation and Language · Computer Science 2024-02-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang

Large Language Models have become the core architecture upon which most modern natural language processing (NLP) systems build. These models can consistently deliver impressive accuracy and robustness across tasks and domains, but their…

Computation and Language · Computer Science 2023-04-07 Daniel Campos , Alexandre Marques , Tuan Nguyen , Mark Kurtz , ChengXiang Zhai

Large language models (LLMs) have achieved great success in medical question answering and clinical decision-making, promoting the efficiency and popularization of the personalized virtual doctor in society. However, the traditional…

Computation and Language · Computer Science 2025-09-23 Jianbin Zhang , Yulin Zhu , Wai Lun Lo , Richard Tai-Chiu Hsung , Harris Sik-Ho Tsang , Kai Zhou

Fueled by their remarkable ability to tackle diverse tasks across multiple domains, large language models (LLMs) have grown at an unprecedented rate, with some recent models containing trillions of parameters. This growth is accompanied by…

Machine Learning · Computer Science 2025-05-30 Athanasios Glentis , Jiaxiang Li , Qiulin Shang , Andi Han , Ioannis Tsaknakis , Quan Wei , Mingyi Hong

Large Language Models (LLMs) have shown remarkable success in supporting a wide range of knowledge-intensive tasks. In specialized domains, there is growing interest in leveraging LLMs to assist subject matter experts with domain-specific…

Computation and Language · Computer Science 2025-12-01 Aman Kumar , Ekant Muljibhai Amin , Xian Yeow Lee , Lasitha Vidyaratne , Ahmed K. Farahat , Dipanjan D. Ghosh , Yuta Koreeda , Chetan Gupta

Large Language Models (LLMs) have demonstrated remarkable performance across various natural language tasks, marking significant strides towards general artificial intelligence. While general artificial intelligence is leveraged by…

Computation and Language · Computer Science 2023-10-31 Yizhe Yang , Huashan Sun , Jiawei Li , Runheng Liu , Yinghao Li , Yuhang Liu , Heyan Huang , Yang Gao

Pretraining large language models (LLMs) on vast and heterogeneous datasets is crucial for achieving state-of-the-art performance across diverse downstream tasks. However, current training paradigms treat all samples equally, overlooking…

Machine Learning · Computer Science 2025-02-11 Daouda Sow , Herbert Woisetschläger , Saikiran Bulusu , Shiqiang Wang , Hans-Arno Jacobsen , Yingbin Liang
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