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Effective diabetes management requires continuous monitoring of glycemic levels. Clinically, glycemic control is assessed using metrics such as Time in Range (TIR), Time Below Range (TBR), and Time Above Range (TAR), typically derived from…

Machine Learning · Computer Science 2026-05-21 Canyu Lei , David Repaske , Jianxin Xie

Feature selection poses a challenge in small-sample high-dimensional datasets, where the number of features exceeds the number of observations, as seen in microarray, gene expression, and medical datasets. There isn't a universally optimal…

Machine Learning · Computer Science 2024-07-23 Hossein Nematzadeh , Joseph Mani , Zahra Nematzadeh , Ebrahim Akbari , Radziah Mohamad

Diabetes mellitus is a disease that affects to hundreds of millions of people worldwide. Maintaining a good control of the disease is critical to avoid severe long-term complications. In recent years, several artificial pancreas systems…

Neural and Evolutionary Computing · Computer Science 2023-05-09 J. Ignacio Hidalgo , J. Manuel Colmenar , José L. Risco-Martín , Alfredo Cuesta-Infante , Esther Maqueda , Marta Botella , José Antonio Rubio

We consider the high-dimensional discriminant analysis problem. For this problem, different methods have been proposed and justified by establishing exact convergence rates for the classification risk, as well as the l2 convergence results…

Machine Learning · Statistics 2013-06-28 Mladen Kolar , Han Liu

Background: Accurate week-ahead forecasts of continuous glucose monitoring (CGM) derived metrics could enable proactive diabetes management, but relative performance of modern tabular learning approaches is incompletely defined. Methods: We…

Other Quantitative Biology · Quantitative Biology 2026-01-05 Simon Lebech Cichosz , Stine Hangaard , Thomas Kronborg , Peter Vestergaard , Morten Hasselstrøm Jensen

A common goal in observational research is to estimate marginal causal effects in the presence of confounding variables. One solution to this problem is to use the covariate distribution to weight the outcomes such that the data appear…

Methodology · Statistics 2020-08-18 Kevin P. Josey , Elizabeth Juarez-Colunga , Fan Yang , Debashis Ghosh

Continuous response variables often need to be transformed to meet regression modeling assumptions; however, finding the optimal transformation is challenging and results may vary with the choice of transformation. When a continuous…

Methodology · Statistics 2022-07-19 Yuqi Tian , Bryan E. Shepherd , Chun Li , Donglin Zeng , Jonathan J. Schildcrout

Optical continuous glucose monitoring (CGM) systems are emerging for personalized glucose management owing to their lower cost and prolonged durability compared to conventional electrochemical CGMs. Here, we report a computational CGM…

Effectively controlling the false discovery rate (FDR) in high-dimensional variable selection is a fundamental statistical problem that has garnered significant research interest. In this paper, we propose a novel, user-friendly, and…

Methodology · Statistics 2026-04-28 Yujia Wu , Panxu Yuan , Binyan Jiang

Graphical modeling explores dependences among a collection of variables by inferring a graph that encodes pairwise conditional independences. For jointly Gaussian variables, this translates into detecting the support of the precision…

Methodology · Statistics 2018-02-16 Shota Katayama , Hironori Fujisawa , Mathias Drton

Diffusion approximation provides weak approximation for stochastic gradient descent algorithms in a finite time horizon. In this paper, we introduce new tools motivated by the backward error analysis of numerical stochastic differential…

Machine Learning · Computer Science 2019-09-05 Yuanyuan Feng , Tingran Gao , Lei Li , Jian-Guo Liu , Yulong Lu

Medical time series analysis is challenging due to data sparsity, noise, and highly variable recording lengths. Prior work has shown that stochastic sparse sampling effectively handles variable-length signals, while retrieval-augmented…

Machine Learning · Computer Science 2025-10-06 Aydin Javadov , Samir Garibov , Tobias Hoesli , Qiyang Sun , Florian von Wangenheim , Joseph Ollier , Björn W. Schuller

Simultaneously performing variable selection and inference in high-dimensional regression models is an open challenge in statistics and machine learning. The increasing availability of vast amounts of variables requires the adoption of…

Methodology · Statistics 2025-05-08 Marco Molinari , Magne Thoresen

We present an implementation of the coherent dedispersion algorithm capable of dedispersing high-time-resolution radio observations to many different dispersion measures (DMs). This approach allows the removal of the dispersive effects of…

Instrumentation and Methods for Astrophysics · Physics 2016-07-05 C. G. Bassa , Z. Pleunis , J. W. T. Hessels

In microbiome studies, it is often of great interest to identify clusters or partitions of microbiome profiles within a study population and to characterize the distinctive attributes of each resulting microbial community. While raw counts…

Methodology · Statistics 2025-08-18 Zhongmao Liu , Xiaohui Yin , Yanjiao Zhou , Gen Li , Kun Chen

Machine learning shows remarkable success for recognizing patterns in data. Here we apply the machine learning (ML) for the diagnosis of early stage diabetes, which is known as a challenging task in medicine. Blood glucose levels are…

Quantitative Methods · Quantitative Biology 2021-02-24 Woo Seok Lee , Junghyo Jo , Taegeun Song

In multi-state models based on high-dimensional data, effective modeling strategies are required to determine an optimal, ideally parsimonious model. In particular, linking covariate effects across transitions is needed to conduct joint…

Methodology · Statistics 2024-11-27 Kaya Miah , Jelle J. Goeman , Hein Putter , Annette Kopp-Schneider , Axel Benner

This paper explores the homogeneity of coefficients in high-dimensional regression, which extends the sparsity concept and is more general and suitable for many applications. Homogeneity arises when one expects regression coefficients…

Methodology · Statistics 2013-04-01 Tracy Ke , Jianqing Fan , Yichao Wu

Sparse linear regression is a central problem in high-dimensional statistics. We study the correlated random design setting, where the covariates are drawn from a multivariate Gaussian $N(0,\Sigma)$, and we seek an estimator with small…

Data Structures and Algorithms · Computer Science 2023-05-29 Jonathan Kelner , Frederic Koehler , Raghu Meka , Dhruv Rohatgi

Though Gaussian graphical models have been widely used in many scientific fields, relatively limited progress has been made to link graph structures to external covariates. We propose a Gaussian graphical regression model, which regresses…

Methodology · Statistics 2022-02-01 Jingfei Zhang , Yi Li
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