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Continuous glucose monitoring (CGM) is a minimally invasive technology that measures blood glucose every few minutes for weeks or months at a time. CGM data are often collected in the free-living environment and is strongly related to…

Methodology · Statistics 2025-09-04 Marcos Matabuena , Ciprian M. Crainiceanu

Understanding how biomarker distributions evolve over time is a central challenge in digital health and chronic disease monitoring. In diabetes, changes in the distribution of glucose measurements can reveal patterns of disease progression…

Machine Learning · Statistics 2026-03-26 Antonio Álvarez-López , Marcos Matabuena

Distribution-as-response regression problems are gaining wider attention, especially within biomedical settings where observation-rich patient specific data sets are available, such as feature densities in CT scans (Petersen et al., 2021)…

Computation · Statistics 2025-12-22 Alexander Coulter , Rebecca Lee , Irina Gaynanova

Modeling the dynamics of probability distributions from time-dependent data samples is a fundamental problem in many fields, including digital health. The goal is to analyze how the distribution of a biomarker, such as glucose, changes over…

Machine Learning · Statistics 2025-09-18 Antonio Álvarez-López , Marcos Matabuena

The rising rates of diabetes necessitate innovative methods for its management. Continuous glucose monitors (CGM) are small medical devices that measure blood glucose levels at regular intervals providing insights into daily patterns of…

Quantitative Methods · Quantitative Biology 2024-10-10 Renat Sergazinov , Elizabeth Chun , Valeriya Rogovchenko , Nathaniel Fernandes , Nicholas Kasman , Irina Gaynanova

Biosensor data has the potential ability to improve disease control and detection. However, the analysis of these data under free-living conditions is not feasible with current statistical techniques. To address this challenge, we introduce…

Applications · Statistics 2021-03-30 Marcos Matabuena , Alexander Petersen , Juan C. Vidal , Francisco Gude

With the development of next generation sequencing technology, researchers have now been able to study the microbiome composition using direct sequencing, whose output are bacterial taxa counts for each microbiome sample. One goal of…

Applications · Statistics 2013-05-24 Jun Chen , Hongzhe Li

Continuous glucose monitoring (CGM) data has revolutionized the management of type 1 diabetes, particularly when integrated with insulin pumps to mitigate clinical events such as hypoglycemia. Recently, there has been growing interest in…

Continuous glucose monitors (CGMs) are increasingly used to measure blood glucose levels and provide information about the treatment and management of diabetes. Our motivating study contains CGM data during sleep for 174 study participants…

As continuous glucose monitors (CGMs) are used increasingly by diabetic patients, new and intuitive tools are needed to help patients and their physicians use these streams of data to improve blood glucose management. In this paper, we…

Quantitative Methods · Quantitative Biology 2013-05-15 Edward Aboufadel

The global diabetes epidemic highlights the importance of maintaining good glycemic control. Glucose prediction is a fundamental aspect of diabetes management, facilitating real-time decision-making. Recent research has introduced models…

Artificial Intelligence · Computer Science 2024-04-19 Ming Cheng , Xingjian Diao , Ziyi Zhou , Yanjun Cui , Wenjun Liu , Shitong Cheng

Fr\'echet regression is becoming a mainstay in modern data analysis for analyzing non-traditional data types belonging to general metric spaces. This novel regression method is especially useful in the analysis of complex health data such…

Methodology · Statistics 2024-10-23 Abdul-Nasah Soale , Congli Ma , Siyu Chen , Obed Koomson

The classification of diabetes and prediabetes by static glucose thresholds obscures the pathophysiological dysglycemia heterogeneity, primarily driven by insulin resistance (IR), beta-cell dysfunction, and incretin deficiency. This review…

Machine Learning · Computer Science 2025-11-07 Ahmed A. Metwally , Heyjun Park , Yue Wu , Tracey McLaughlin , Michael P. Snyder

Control of blood glucose is essential for diabetes management. Current digital therapeutic approaches for subjects with Type 1 diabetes mellitus (T1DM) such as the artificial pancreas and insulin bolus calculators leverage machine learning…

Computer Vision and Pattern Recognition · Computer Science 2019-02-27 Kezhi Li , John Daniels , Chengyuan Liu , Pau Herrero , Pantelis Georgiou

Describing dynamic medical systems using machine learning is a challenging topic with a wide range of applications. In this work, the possibility of modeling the blood glucose level of diabetic patients purely on the basis of measured data…

Machine Learning · Computer Science 2023-03-10 David Jödicke , Daniel Parra , Gabriel Kronberger , Stephan Winkler

A task of vital clinical importance, within Diabetes management, is the prevention of hypo/hyperglycemic events. Increasingly adopted Continuous Glucose Monitoring (CGM) devices offer detailed, non-intrusive and real time insights into a…

Machine Learning · Computer Science 2023-03-09 Jakub J. Dylag

With continuous glucose monitoring (CGM), data-driven models on blood glucose prediction have been shown to be effective in related work. However, such (CGM) systems are not always available, e.g., for a patient at home. In this work, we…

Computers and Society · Computer Science 2024-04-10 Tu Nguyen , Markus Rokicki

Continuous Glucose Monitoring (CGM) has enabled important opportunities for diabetes management. This study explores the use of CGM data as input for digital decision support tools. We investigate how Recurrent Neural Networks (RNNs) can be…

Continuous glucose monitoring (CGM) has been increasingly used in US hospitals for the care of patients with diabetes. Time in range (TIR), which measures the percent of time over a specified time window with glucose values within a target…

Methodology · Statistics 2024-10-07 Qi Yu , Guillermo E. Umpierrez , Limin Peng

Continuous Blood Glucose (CGM) monitors have revolutionized the ability of diabetics to manage their blood glucose, and paved the way for artificial pancreas systems. In this paper we augment CGM data with sensor input collected by a smart…

Human-Computer Interaction · Computer Science 2023-02-06 Sam Royston
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