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Related papers: CIDGMed: Causal Inference-Driven Medication Recomm…

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Medication recommendation using Electronic Health Records (EHR) is challenging due to complex medical data. Current approaches extract longitudinal information from patient EHR to personalize recommendations. However, existing models often…

Machine Learning · Computer Science 2023-09-27 Jiacong Mi , Yi Zu , Zhuoyuan Wang , Jieyue He

Knowledge Graphs have been one of the fundamental methods for integrating heterogeneous data sources. Integrating heterogeneous data sources is crucial, especially in the biomedical domain, where central data-driven tasks such as drug…

Machine Learning · Computer Science 2020-12-22 Islam Akef Ebeid , Majdi Hassan , Tingyi Wanyan , Jack Roper , Abhik Seal , Ying Ding

Due to the lack of fine-grained annotation guidance, current Multiple Instance Learning (MIL) struggles to establish a robust causal relationship between Whole Slide Image (WSI) diagnosis and evidence sub-images, just like fully supervised…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Tianhang Nan , Yong Ding , Hao Quan , Deliang Li , Lisha Li , Guanghong Zhao , Xiaoyu Cui

Effective recommender systems play a crucial role in accurately capturing user and item attributes that mirror individual preferences. Some existing recommendation techniques have started to shift their focus towards modeling various types…

Information Retrieval · Computer Science 2025-06-26 Xiang Li , Chaofan Fu , Zhongying Zhao , Guanjie Zheng , Chao Huang , Yanwei Yu , Junyu Dong

Medication Recommendation (MR) is a promising research topic which booms diverse applications in the healthcare and clinical domains. However, existing methods mainly rely on sequential modeling and static graphs for representation…

Machine Learning · Computer Science 2025-01-16 Guanlin Liu , Xiaomei Yu , Zihao Liu , Xue Li , Xingxu Fan , Xiangwei Zheng

Session-based recommendation which has been witnessed a booming interest recently, focuses on predicting a user's next interested item(s) based on an anonymous session. Most existing studies adopt complex deep learning techniques (e.g.,…

Information Retrieval · Computer Science 2023-05-18 Huizi Wu , Cong Geng , Hui Fang

In clinical practice, crossmodal information including medical images and tabular data is essential for disease diagnosis. There exists a significant modality gap between these data types, which obstructs advancements in crossmodal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Tianling Liu , Hongying Liu , Fanhua Shang , Lequan Yu , Tong Han , Liang Wan

Historical prescriptions and selected candidate drugs relevant to the current visit serve as important references for medication recommendation. However, in the absence of explicit intrinsic principles for semantic composition, existing…

Computational Engineering, Finance, and Science · Computer Science 2026-01-28 Yanda Wang , Weitong Chen , Chao Tan , Ian Nabney , Lin Yue , Genlin Ji

Treatment planning for chronic diseases is a critical task in medical artificial intelligence, particularly in traditional Chinese medicine (TCM). However, generating optimized sequential treatment strategies for patients with chronic…

Artificial Intelligence · Computer Science 2023-04-26 Kuo Yang , Zecong Yu , Xin Su , Xiong He , Ning Wang , Qiguang Zheng , Feidie Yu , Zhuang Liu , Tiancai Wen , Xuezhong Zhou

Multimodal learning aims to leverage information from diverse data modalities to achieve more comprehensive performance. However, conventional multimodal models often suffer from modality imbalance, where one or a few modalities dominate…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Mohammed Rakib , Arunkumar Bagavathi

Multimodal deep learning has been used to predict clinical endpoints and diagnoses from clinical routine data. However, these models suffer from scaling issues: they have to learn pairwise interactions between each piece of information in…

Deep learning is typically performed by learning a neural network solely from data in the form of input-output pairs ignoring available domain knowledge. In this work, the Constraint Guided Gradient Descent (CGGD) framework is proposed that…

Artificial Intelligence · Computer Science 2022-06-15 Quinten Van Baelen , Peter Karsmakers

Dynamic treatment regimes (DTRs) are used in medicine to tailor sequential treatment decisions to patients by considering patient heterogeneity. Common methods for learning optimal DTRs, however, have shortcomings: they are typically based…

Machine Learning · Statistics 2023-06-21 Theresa Blümlein , Joel Persson , Stefan Feuerriegel

Although understanding and characterizing causal effects have become essential in observational studies, it is challenging when the confounders are high-dimensional. In this article, we develop a general framework $\textit{CausalEGM}$ for…

Machine Learning · Statistics 2023-03-20 Qiao Liu , Zhongren Chen , Wing Hung Wong

Recent progress in deep learning is revolutionizing the healthcare domain including providing solutions to medication recommendations, especially recommending medication combination for patients with complex health conditions. Existing…

Artificial Intelligence · Computer Science 2019-03-08 Junyuan Shang , Cao Xiao , Tengfei Ma , Hongyan Li , Jimeng Sun

Accurate prediction of protein-ligand binding affinity plays a pivotal role in accelerating the discovery of novel drugs and vaccines, particularly for gastrointestinal (GI) diseases such as gastric ulcers, Crohn's disease, and ulcerative…

Machine Learning · Computer Science 2025-11-11 Ziyang Gao , Annie Cheung , Yihao Ou

Background: Computational drug repurposing is a cost- and time-efficient approach that aims to identify new therapeutic targets or diseases (indications) of existing drugs/compounds. It is especially critical for emerging and/or orphan…

Quantitative Methods · Quantitative Biology 2023-04-26 Chunyu Ma , Zhihan Zhou , Han Liu , David Koslicki

Medication recommendation systems have gained significant attention in healthcare as a means of providing tailored and effective drug combinations based on patients' clinical information. However, existing approaches often suffer from…

Machine Learning · Computer Science 2024-08-13 Zihao Zhao , Yi Jing , Fuli Feng , Jiancan Wu , Chongming Gao , Xiangnan He

Ophthalmologists typically require multimodal data sources to improve diagnostic accuracy in clinical decisions. However, due to medical device shortages, low-quality data and data privacy concerns, missing data modalities are common in…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Chengzhi Liu , Zile Huang , Zhe Chen , Feilong Tang , Yu Tian , Zhongxing Xu , Zihong Luo , Yalin Zheng , Yanda Meng

With the growing imbalance between limited medical resources and escalating demands, AI-based clinical tasks have become paramount. As a sub-domain, medication recommendation aims to amalgamate longitudinal patient history with medical…

Artificial Intelligence · Computer Science 2023-11-28 Xiang Li , Shunpan Liang , Yulei Hou , Tengfei Ma