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The angular momentum of molecules, or, equivalently, their rotation in three-dimensional space, is ideally suited for quantum control. Molecular angular momentum is naturally quantized, time evolution is governed by a well-known Hamiltonian…

Quantum Physics · Physics 2019-10-23 Christiane P. Koch , Mikhail Lemeshko , Dominique Sugny

Quantum algorithms have shown promise in solving Quadratic Unconstrained Binary Optimization (QUBO) problems, benefiting from their connection to the transverse field Ising model. Various Ising solvers, both classical and quantum, have…

Optimization and Control · Mathematics 2025-09-16 Zedong Peng , Daniel de Roux , David E. Bernal Neira

A unitary coupled-cluster (UCC) form for the wavefunction in the variational quantum eigensolver has been suggested as a systematic way to go beyond the mean-field approximation and include electron correlation in solving quantum chemistry…

Quantum Physics · Physics 2018-09-12 Ilya G. Ryabinkin , Tzu-Ching Yen , Scott N. Genin , Artur F. Izmaylov

With the advent of exascale computing, effective load balancing in massively parallel software applications is critically important for leveraging the full potential of high performance computing systems. Load balancing is the distribution…

Quantum Physics · Physics 2025-01-30 Omer Rathore , Alastair Basden , Nicholas Chancellor , Halim Kusumaatmaja

Variational quantum algorithms constitute one of the most widespread methods for using current noisy quantum computers. However, it is unknown if these heuristic algorithms provide any quantum-computational speedup, although we cannot…

Optimization of electricity surplus is a crucial element for transmission power networks to reduce costs and efficiently use the available electricity across the network. In this paper we showed how to optimize such a network with quantum…

Quantum Physics · Physics 2022-12-06 Giuseppe Colucci , Stan van der Linde , Frank Phillipson

Edge computing is a promising technology that offers a superior user experience and enables various innovative Internet of Things applications. In this paper, we present a mixed-integer linear programming (MILP) model for optimal edge…

Quantum Physics · Physics 2023-06-05 Duong The Do , Ni Trieu , Duong Tung Nguyen

This paper proposes a novel dispatch formulation for micro-mobility vehicles using a Quantum Annealer (QA). In recent years, QA has gained increasing attention as a high-performance solver for combinatorial optimization problems. Meanwhile,…

Quantum Physics · Physics 2026-01-30 Takeru Goto , Masayuki Ohzeki

The Hubbard model has occupied the minds of condensed matter physicists for most part of the last century. This model provides insight into a range of phenomena in correlated electron systems. We wish to examine the paradigm of quantum…

Quantum Physics · Physics 2026-05-12 Kunal Vyas , Fengping Jin , Hans De Raedt , Kristel Michielsen

Quantum annealing aims at solving hard computational problems through adiabatic state preparation. Here, I propose to use inhomogeneous longitudinal magnetic fields to enhance the efficiency of the annealing. Such fields are able to bias…

Quantum Physics · Physics 2019-09-23 Tobias Graß

Quantum annealing is a novel type of analog computation that aims to use quantum mechanical fluctuations to search for optimal solutions of Ising problems. Quantum annealing in the Transverse Ising model, implemented on D-Wave QPUs, are…

Quantum Physics · Physics 2025-03-14 Elijah Pelofske

Uncertainty is fundamental in modern power systems, where renewable generation and fluctuating demand make stochastic optimization indispensable. The chance constrained unit commitment problem (UCP) captures this uncertainty but rapidly…

Quantum Physics · Physics 2025-12-04 David Ribes , Tatiana Gonzalez Grandon

Determining the binding pose of a ligand to a protein, known as molecular docking, is a fundamental task in drug discovery. Generative approaches promise faster, improved, and more diverse pose sampling than physics-based methods, but are…

Machine Learning · Computer Science 2026-03-26 Alvaro Prat , Leo Zhang , Charlotte M. Deane , Yee Whye Teh , Garrett M. Morris

Recent advances in high-throughput genomic technologies coupled with exponential increases in computer processing and memory have allowed us to interrogate the complex aberrant molecular underpinnings of human disease from a genome-wide…

Recent advances in quantum technology have led to the development and manufacturing of experimental programmable quantum annealers that promise to solve certain combinatorial optimization problems of practical relevance faster than their…

Quantum Physics · Physics 2016-05-31 Itay Hen , Federico M. Spedalieri

Quantum error correction is one of the most important milestones for realization of large-scale quantum computation. To achieve this, it is essential not only to integrate a large number of qubits with high fidelity, but also to build a…

Quantum Physics · Physics 2023-08-07 Jun Fujisaki , Hirotaka Oshima , Shintaro Sato , Keisuke Fujii

Accelerating molecular docking -- the process of predicting how molecules bind to protein targets -- could boost small-molecule drug discovery and revolutionize medicine. Unfortunately, current molecular docking tools are too slow to screen…

Quantum annealing provides a promising route for the development of quantum optimization devices, but the usefulness of such devices will be limited in part by the range of implementable problems as dictated by hardware constraints. To…

Quantum Physics · Physics 2015-10-14 Walter Vinci , Tameem Albash , Gerardo Paz-Silva , Itay Hen , Daniel A. Lidar

The complexity of biological systems, governed by molecular interactions across hierarchical scales, presents a challenge for computational modeling. While advances in multiomic profiling have enabled precise measurements of biological…

Quantum Physics · Physics 2025-06-18 Michael Kubal , Sonika Johri

In recent years, formulating various combinatorial optimization problems as Quadratic Unconstrained Binary Optimization (QUBO) has gained significant attention as a promising approach for efficiently obtaining optimal or near-optimal…

Optimization and Control · Mathematics 2025-04-14 Kyo Kuroki , Thiem Van Chu , Masato Motomura , Kazushi Kawamura
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