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Diffusion models, though originally designed for generative tasks, have demonstrated impressive self-supervised representation learning capabilities. A particularly intriguing phenomenon in these models is the emergence of unimodal…

Machine Learning · Computer Science 2026-02-04 Xiao Li , Zekai Zhang , Xiang Li , Siyi Chen , Zhihui Zhu , Peng Wang , Qing Qu

Diffusion Probabilistic Models (DPMs) are powerful generative models that have achieved unparalleled success in a number of generative tasks. In this work, we aim to build inductive biases into the training and sampling of diffusion models…

Machine Learning · Computer Science 2025-03-14 Thomas Jiralerspong , Berton Earnshaw , Jason Hartford , Yoshua Bengio , Luca Scimeca

Accurately identifying oocytes that progress to the blastocyst stage is crucial in reproductive medicine, but the limited availability of annotated high-quality embryo images presents challenges for developing automated diagnostic tools. To…

Quantitative Methods · Quantitative Biology 2025-06-18 Alejandro Golfe , Natalia P. García-de-la-puente , Adrián Colomer , Valery Naranjo

We introduce OneDiffusion, a versatile, large-scale diffusion model that seamlessly supports bidirectional image synthesis and understanding across diverse tasks. It enables conditional generation from inputs such as text, depth, pose,…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Duong H. Le , Tuan Pham , Sangho Lee , Christopher Clark , Aniruddha Kembhavi , Stephan Mandt , Ranjay Krishna , Jiasen Lu

There is strong empirical evidence that the state-of-the-art diffusion modeling paradigm leads to models that memorize the training set, especially when the training set is small. Prior methods to mitigate the memorization problem often…

Machine Learning · Computer Science 2026-03-03 Kulin Shah , Alkis Kalavasis , Adam R. Klivans , Giannis Daras

Recent advancements in diffusion models have demonstrated significant success in unsupervised anomaly segmentation. For anomaly segmentation, these models are first trained on normal data; then, an anomalous image is noised to an…

Computer Vision and Pattern Recognition · Computer Science 2025-08-08 Mehrdad Moradi , Kamran Paynabar

Methods for out-of-distribution (OOD) detection that scale to 3D data are crucial components of any real-world clinical deep learning system. Classic denoising diffusion probabilistic models (DDPMs) have been recently proposed as a robust…

In recent years, diffusion models (DMs) have become a popular method for generating synthetic data. By achieving samples of higher quality, they quickly became superior to generative adversarial networks (GANs) and the current…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Denisa Qosja , Simon Wagner , Daniel O'Hagan

Multi-modality image fusion aims to combine different modalities to produce fused images that retain the complementary features of each modality, such as functional highlights and texture details. To leverage strong generative priors and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-24 Zixiang Zhao , Haowen Bai , Yuanzhi Zhu , Jiangshe Zhang , Shuang Xu , Yulun Zhang , Kai Zhang , Deyu Meng , Radu Timofte , Luc Van Gool

Ensuring the robustness of deep learning models requires comprehensive and diverse testing. Existing approaches, often based on simple data augmentation techniques or generative adversarial networks, are limited in producing realistic and…

Computer Vision and Pattern Recognition · Computer Science 2025-02-10 Luciano Baresi , Davide Yi Xian Hu , Muhammad Irfan Mas'udi , Giovanni Quattrocchi

In recent years, diffusion models (DMs) have drawn significant attention for their success in approximating data distributions, yielding state-of-the-art generative results. Nevertheless, the versatility of these models extends beyond their…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Peter Lorenz , Ricard Durall , Janis Keuper

Detecting visual anomalies in diverse, multi-class real-world images is a significant challenge. We introduce \ours, a novel unsupervised multi-class visual anomaly detection framework. It integrates a Latent Diffusion Model (LDM) with a…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Samet Hicsonmez , Abd El Rahman Shabayek , Djamila Aouada

Molecule generation, especially generating 3D molecular geometries from scratch (i.e., 3D \textit{de novo} generation), has become a fundamental task in drug designs. Existing diffusion-based 3D molecule generation methods could suffer from…

Machine Learning · Computer Science 2022-09-14 Lei Huang , Hengtong Zhang , Tingyang Xu , Ka-Chun Wong

Denoising Probabilistic Models (DPMs) represent an emerging domain of generative models that excel in generating diverse and high-quality images. However, most current training methods for DPMs often neglect the correlation between…

Computer Vision and Pattern Recognition · Computer Science 2024-02-01 Viet Nguyen , Giang Vu , Tung Nguyen Thanh , Khoat Than , Toan Tran

Diffusion models are highly regarded for their controllability and the diversity of images they generate. However, class-conditional generation methods based on diffusion models often focus on more common categories. In large-scale…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Kun Wang , Donglin Di , Tonghua Su , Lei Fan

Denoising diffusion models are a powerful type of generative models used to capture complex distributions of real-world signals. However, their applicability is limited to scenarios where training samples are readily available, which is not…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Ayush Tewari , Tianwei Yin , George Cazenavette , Semon Rezchikov , Joshua B. Tenenbaum , Frédo Durand , William T. Freeman , Vincent Sitzmann

Omnidirectional images (ODIs) are commonly used in real-world visual tasks, and high-resolution ODIs help improve the performance of related visual tasks. Most existing super-resolution methods for ODIs use end-to-end learning strategies,…

Computer Vision and Pattern Recognition · Computer Science 2024-04-18 Runyi Li , Xuhan Sheng , Weiqi Li , Jian Zhang

Predictive models trained on imbalanced data tend to produce biased results. This problem is exacerbated when there is not just one output label, but a set of them. This is the case for multilabel learning (MLL) algorithms used to classify…

Machine Learning · Computer Science 2025-01-22 Francisco Charte , Miguel Ángel Dávila , María Dolores Pérez-Godoy , María José del Jesus

Generative adversarial networks (GANs) are frequently utilized in astronomy to construct an emulator of numerical simulations. Nevertheless, training GANs can prove to be a precarious task, as they are prone to instability and often lead to…

Instrumentation and Methods for Astrophysics · Physics 2023-11-14 Xiaosheng Zhao , Yuan-Sen Ting , Kangning Diao , Yi Mao

The goal of image ordinal estimation is to estimate the ordinal label of a given image with a convolutional neural network. Existing methods are mainly based on ordinal regression and particularly focus on modeling the ordinal mapping from…

Computer Vision and Pattern Recognition · Computer Science 2023-01-18 Yiming Lei , Zilong Li , Yangyang Li , Junping Zhang , Hongming Shan