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The extraction of $k$-mers is a fundamental component in many complex analyses of large next-generation sequencing datasets, including reads classification in genomics and the characterization of RNA-seq datasets. The extraction of all…

Quantitative Methods · Quantitative Biology 2021-01-19 Diego Santoro , Leonardo Pellegrina , Fabio Vandin

We introduce a pattern mining framework that operates on semi-structured datasets and exploits the dichotomy between outcomes. Our approach takes advantage of constraint reasoning to find sequential patterns that occur frequently and…

Artificial Intelligence · Computer Science 2022-01-25 Xin Wang , Serdar Kadioglu

The search for patterns or motifs in data represents an area of key interest to many researchers. In this paper we present the Motif Tracking Algorithm, a novel immune inspired pattern identification tool that is able to identify variable…

Neural and Evolutionary Computing · Computer Science 2013-06-03 William Wilson , Phil Birkin , Uwe Aickelin

In this paper we present a novel probabilistic sampling-based motion planning algorithm called the Fast Marching Tree algorithm (FMT*). The algorithm is specifically aimed at solving complex motion planning problems in high-dimensional…

Robotics · Computer Science 2015-02-09 Lucas Janson , Edward Schmerling , Ashley Clark , Marco Pavone

One fundamental problem in temporal graph analysis is to count the occurrences of small connected subgraph patterns (i.e., motifs), which benefits a broad range of real-world applications, such as anomaly detection, structure prediction,…

Machine Learning · Computer Science 2022-04-21 Zhongqiang Gao , Chuanqi Cheng , Yanwei Yu , Lei Cao , Chao Huang , Junyu Dong

Since the adoption of large language models (LLMs) for text evaluation has become increasingly prevalent in the field of natural language processing (NLP), a series of existing works attempt to optimize the prompts for LLM evaluators to…

Computation and Language · Computer Science 2025-06-03 Bosi Wen , Pei Ke , Yufei Sun , Cunxiang Wang , Xiaotao Gu , Jinfeng Zhou , Jie Tang , Hongning Wang , Minlie Huang

Since model quantization helps to reduce the model size and computation latency, it has been successfully applied in many applications of mobile phones, embedded devices and smart chips. The mixed-precision quantization model can match…

Computer Vision and Pattern Recognition · Computer Science 2021-03-05 Qigong Sun , Licheng Jiao , Yan Ren , Xiufang Li , Fanhua Shang , Fang Liu

The widespread application of Large Language Models (LLMs) has motivated a growing interest in their capacity for processing dynamic graphs. Temporal motifs, as an elementary unit and important local property of dynamic graphs which can…

Machine Learning · Computer Science 2026-03-09 Bing Hao , Minglai Shao , Zengyi Wo , Yunlong Chu , Yuhang Liu , Ruijie Wang

Inverse design of short single-stranded RNA and DNA sequences (aptamers) is the task of finding sequences that satisfy a set of desired criteria. Relevant criteria may be, for example, the presence of specific folding motifs, binding to…

Schema matching is the process of identifying correspondences between the elements of two given schemata, essential for database management systems, data integration, and data warehousing. For datasets across different scenarios, the…

Databases · Computer Science 2025-03-07 Longyu Feng , Huahang Li , Chen Jason Zhang

The motif-scaffolding problem is a central task in computational protein design: Given the coordinates of atoms in a geometry chosen to confer a desired biochemical function (a motif), the task is to identify diverse protein structures…

Machine Learning · Computer Science 2025-02-20 Zhuoqi Zheng , Bo Zhang , Kieran Didi , Kevin K. Yang , Jason Yim , Joseph L. Watson , Hai-Feng Chen , Brian L. Trippe

Few-shot segmentation is challenging because objects within the support and query images could significantly differ in appearance and pose. Using a single prototype acquired directly from the support image to segment the query image causes…

Computer Vision and Pattern Recognition · Computer Science 2020-09-02 Boyu Yang , Chang Liu , Bohao Li , Jianbin Jiao , Qixiang Ye

Genomic expression depends critically both on the ability of regulatory proteins to locate specific target sites on a DNA within seconds and on the formation of long lived (many minutes) complexes between these proteins and the DNA.…

Soft Condensed Matter · Physics 2011-08-23 O. Bénichou , Y. Kafri , M. Sheinman , R. Voituriez

Various grammar compression algorithms have been proposed in the last decade. A grammar compression is a restricted CFG deriving the string deterministically. An efficient grammar compression develops a smaller CFG by finding duplicated…

Data Structures and Algorithms · Computer Science 2016-09-01 Shouhei Fukunaga , Yoshimasa Takabatake , I Tomohiro , Hiroshi Sakamoto

As language models (LMs) deliver increasing performance on a range of NLP tasks, probing classifiers have become an indispensable technique in the effort to better understand their inner workings. A typical setup involves (1) defining an…

Computation and Language · Computer Science 2024-08-01 Charles Jin , Martin Rinard

A weighted string over an alphabet of size $\sigma$ is a string in which a set of letters may occur at each position with respective occurrence probabilities. Weighted strings, also known as position weight matrices or uncertain sequences,…

Data Structures and Algorithms · Computer Science 2015-12-09 Carl Barton , Chang Liu , Solon P. Pissis

Most of the current understanding of structure-property relations at the molecular and the supramolecular scales can be formulated in terms of the stability of and the interactions between a limited number of recurring structural motifs…

Chemical Physics · Physics 2018-01-29 Piero Gasparotto , Robert Horst Meißner , Michele Ceriotti

The protein design problem involves finding polypeptide sequences folding into a given threedimensional structure. Its rigorous algorithmic solution is computationally demanding, involving a nested search in sequence and structure spaces.…

Quantum Physics · Physics 2024-07-11 Veronica Panizza , Philipp Hauke , Cristian Micheletti , Pietro Faccioli

Motif counting plays a crucial role in understanding the structural properties of networks. By computing motif frequencies, researchers can draw key insights into the structural properties of the underlying network. As networks become…

Social and Information Networks · Computer Science 2025-03-26 Haozhe Yin , Kai Wang , Wenjie Zhang , Yizhang He , Ying Zhang , Xuemin Lin

Identifying frequent subgraphs, also called network motifs, is crucial in analyzing and predicting properties of real-world networks. However, finding large commonly-occurring motifs remains a challenging problem not only due to its NP-hard…

Machine Learning · Computer Science 2024-02-23 Rex Ying , Tianyu Fu , Andrew Wang , Jiaxuan You , Yu Wang , Jure Leskovec