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Spinal surgery planning necessitates automatic segmentation of vertebrae in cone-beam computed tomography (CBCT), an intraoperative imaging modality that is widely used in intervention. However, CBCT images are of low-quality and…
Purpose: Proximal femur image analyses based on quantitative computed tomography (QCT) provide a method to quantify the bone density and evaluate osteoporosis and risk of fracture. We aim to develop a deep-learning-based method for…
Radiographs are used as the most important imaging tool for identifying spine anomalies in clinical practice. The evaluation of spinal bone lesions, however, is a challenging task for radiologists. This work aims at developing and…
Purpose: To examine whether incorporating anatomical awareness into a deep learning model can improve generalizability and enable prediction of disease progression. Methods: This retrospective multicenter study included conventional pelvic…
Computational analysis of whole slide images (WSIs) has seen significant research progress in recent years, with applications ranging across important diagnostic and prognostic tasks such as survival or cancer subtype prediction. Many…
In this paper we present a new 3D segmentation approach for the vertebrae of the lower thoracic and the lumbar spine in spiral computed tomography datasets. We implemented a multi-step procedure. Its main components are deformable models,…
In this paper we introduce the Ladder Algorithm; a novel recurrent algorithm to detect repetitive structures in natural images with high accuracy using little training data. We then demonstrate the algorithm on the task of extracting…
Supervised machine learning algorithms, especially in the medical domain, are affected by considerable ambiguity in expert markings. In this study we address the case where the experts' opinion is obtained as a distribution over the…
Osteoporosis is a common bone disease that increases the risk of bone fracture. Hip-fracture risk screening methods based on finite element analysis depend on segmented computed tomography (CT) images; however, current femur segmentation…
Accurate and reliable registration of longitudinal spine images is essential for assessment of disease progression and surgical outcome. Implementing a fully automatic and robust registration is crucial for clinical use, however, it is…
Osteoporosis is a widespread and chronic metabolic bone disease that often remains undiagnosed and untreated due to limited access to bone mineral density (BMD) tests like Dual-energy X-ray absorptiometry (DXA). In response to this…
In biomechanical modeling, the representation of ligament attachments is crucial for a realistic simulation of the forces acting between the vertebrae. These forces are typically modeled as vectors connecting ligament landmarks on adjacent…
Statistical methods such as sequential Monte Carlo Methods were proposed for detection, segmentation and tracking of objects in digital images. A similar approach, called Shape Particle Filters was introduced for the segmentation of…
We propose a framework for extracting the bone surface from B-mode images employing the eigenspace minimum variance (ESMV) beamformer and a ridge detection method. We show that an ESMV beamformer with a rank-1 signal subspace can preserve…
Wrist pathologies, {particularly fractures common among children and adolescents}, present a critical diagnostic challenge. While X-ray imaging remains a prevalent diagnostic tool, the increasing misinterpretation rates highlight the need…
Scoliosis is a prevalent condition that impacts both physical health and appearance, with adolescent idiopathic scoliosis (AIS) being the most common form. Currently, the main AIS assessment tool, X-rays, poses significant limitations,…
This study introduces a novel unsupervised medical image feature extraction method that employs spatial stratification techniques. An objective function based on weight is proposed to achieve the purpose of fast image recognition. The…
Recent advancements in computer vision promise to automate medical image analysis. Rheumatoid arthritis is an autoimmune disease that would profit from computer-based diagnosis, as there are no direct markers known, and doctors have to rely…
The objective of this paper is to significantly reduce the manual workload required from medical professionals in complex 3D segmentation tasks that cannot be yet fully automated. For instance, in radiotherapy planning, organs at risk must…
We propose a scalable, provably accurate method for localizing an unknown number of multiple axis-aligned anomalous patches in spatial data under a general class of spatial dependence. Motivated by the practical need to detect localized…