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This paper contributes to the "BraTS 2024 Brain MR Image Synthesis Challenge" and presents a conditional Wavelet Diffusion Model (cWDM) for directly solving a paired image-to-image translation task on high-resolution volumes. While deep…

Image and Video Processing · Electrical Eng. & Systems 2024-11-27 Paul Friedrich , Alicia Durrer , Julia Wolleb , Philippe C. Cattin

The diffusion model has recently emerged as a potent approach in computer vision, demonstrating remarkable performances in the field of generative artificial intelligence. Capable of producing high-quality synthetic images, diffusion models…

Image and Video Processing · Electrical Eng. & Systems 2025-05-14 Abdullah , Tao Huang , Ickjai Lee , Euijoon Ahn

The generation of medical images presents significant challenges due to their high-resolution and three-dimensional nature. Existing methods often yield suboptimal performance in generating high-quality 3D medical images, and there is…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Haoshen Wang , Zhentao Liu , Kaicong Sun , Xiaodong Wang , Dinggang Shen , Zhiming Cui

By decomposing the image formation process into a sequential application of denoising autoencoders, diffusion models (DMs) achieve state-of-the-art synthesis results on image data and beyond. Additionally, their formulation allows for a…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Robin Rombach , Andreas Blattmann , Dominik Lorenz , Patrick Esser , Björn Ommer

Advancements in AI for medical imaging offer significant potential. However, their applications are constrained by the limited availability of data and the reluctance of medical centers to share it due to patient privacy concerns.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Marvin Seyfarth , Salman Ul Hassan Dar , Isabelle Ayx , Matthias Alexander Fink , Stefan O. Schoenberg , Hans-Ulrich Kauczor , Sandy Engelhardt

Deep neural networks have brought remarkable breakthroughs in medical image analysis. However, due to their data-hungry nature, the modest dataset sizes in medical imaging projects might be hindering their full potential. Generating…

Diffusion models have achieved remarkable quality in multi-modal MRI synthesis, but their computational cost (hundreds of sampling steps and separate models per modality) limits clinical deployment. We observe that this inefficiency stems…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Yalcin Tur , Mihajlo Stojkovic , Ulas Bagci

In medical imaging, the diffusion models have shown great potential for synthetic image generation tasks. However, these approaches often lack the interpretable connections between the generated and real images and can create anatomically…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Jian-Qing Zheng , Yuanhan Mo , Yang Sun , Jiahua Li , Fuping Wu , Ziyang Wang , Tonia Vincent , Bartłomiej W. Papież

Diffusion models have achieved promising results in image restoration tasks, yet suffer from time-consuming, excessive computational resource consumption, and unstable restoration. To address these issues, we propose a robust and efficient…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Hai Jiang , Ao Luo , Songchen Han , Haoqiang Fan , Shuaicheng Liu

Diffusion MRI (dMRI) is an advanced imaging technique characterizing tissue microstructure and white matter structural connectivity of the human brain. The demand for high-quality dMRI data is growing, driven by the need for better…

Image and Video Processing · Electrical Eng. & Systems 2024-08-26 Xi Zhu , Wei Zhang , Yijie Li , Lauren J. O'Donnell , Fan Zhang

Deep generative modeling has emerged as a powerful tool for synthesizing realistic medical images, driving advances in medical image analysis, disease diagnosis, and treatment planning. This chapter explores various deep generative models…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Paul Friedrich , Yannik Frisch , Philippe C. Cattin

Healthy tissue inpainting has significant applications, including the generation of pseudo-healthy baselines for tumor growth models and the facilitation of image registration. In previous editions of the BraTS Local Synthesis of Healthy…

Image and Video Processing · Electrical Eng. & Systems 2025-07-18 Alicia Durrer , Florentin Bieder , Paul Friedrich , Bjoern Menze , Philippe C. Cattin , Florian Kofler

Magnetic Resonance (MR) imaging plays an essential role in contemporary clinical diagnostics. It is increasingly integrated into advanced therapeutic workflows, such as hybrid Positron Emission Tomography/Magnetic Resonance (PET/MR) imaging…

Image and Video Processing · Electrical Eng. & Systems 2025-07-17 Jiaxu Zheng , Meiman He , Xuhui Tang , Xiong Wang , Tuoyu Cao , Tianyi Zeng , Lichi Zhang , Chenyu You

Diffusion models are the de facto approach for generating high-quality images and videos, but learning high-dimensional models remains a formidable task due to computational and optimization challenges. Existing methods often resort to…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Jiatao Gu , Shuangfei Zhai , Yizhe Zhang , Josh Susskind , Navdeep Jaitly

Diffusion models have revolutionized image generation, yet several challenges restrict their application to large-image domains, such as digital pathology and satellite imagery. Given that it is infeasible to directly train a model on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Srikar Yellapragada , Alexandros Graikos , Kostas Triaridis , Prateek Prasanna , Rajarsi R. Gupta , Joel Saltz , Dimitris Samaras

Latent Diffusion Models (LDMs) enable high-quality image synthesis while avoiding excessive compute demands by training a diffusion model in a compressed lower-dimensional latent space. Here, we apply the LDM paradigm to high-resolution…

Computer Vision and Pattern Recognition · Computer Science 2023-12-29 Andreas Blattmann , Robin Rombach , Huan Ling , Tim Dockhorn , Seung Wook Kim , Sanja Fidler , Karsten Kreis

In the medical domain, acquiring large datasets is challenging due to both accessibility issues and stringent privacy regulations. Consequently, data availability and privacy protection are major obstacles to applying machine learning in…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Wenwu Tang , Khaled Seyam , Bin Yang

Latest diffusion-based methods for many image restoration tasks outperform traditional models, but they encounter the long-time inference problem. To tackle it, this paper proposes a Wavelet-Based Diffusion Model (WaveDM). WaveDM learns the…

Computer Vision and Pattern Recognition · Computer Science 2024-01-26 Yi Huang , Jiancheng Huang , Jianzhuang Liu , Mingfu Yan , Yu Dong , Jiaxi Lv , Chaoqi Chen , Shifeng Chen

In this article, we present a Latent Diffusion Model (LDM) for the generation of brain Magnetic Resonance Imaging (MRI), conditioning its generation based on pathology (Healthy, Glioblastoma, Sclerosis, Dementia) and acquisition modality…

The scarcity of publicly available medical imaging data limits the development of effective AI models. This work proposes a memory-efficient patch-wise denoising diffusion probabilistic model (DDPM) for generating synthetic medical images,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-17 Kathrin Khadra , Utku Türkbey
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