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We investigated the beat-to-beat fluctuation of the photoplethysmography (PPG) waveform. The motivation is that morphology variability extracted from the arterial blood pressure (ABP) has been found to correlate with baseline condition and…

Quantitative Methods · Quantitative Biology 2025-03-20 Yu-Chieh Ho , Te-Sheng Lin , She-Chih Wang , Chen-Shi Chang , Yu-Ting Lin

A deeper understanding of the influence of common cardiovascular diseases like stenosis, aneurysm or atherosclerosis on the circulatory mechanism is required, to establish new methods for early diagnosis. Different types of simulators were…

We use approximate Bayesian computation (ABC) to estimate unknown parameter values, as well as their uncertainties, in Reynolds-averaged Navier-Stokes (RANS) simulations of turbulent flows. The ABC method approximates posterior…

Fluid Dynamics · Physics 2020-11-04 Olga A. Doronina , Scott M. Murman , Peter E. Hamlington

Anemia is a prevalent medical condition that typically requires invasive blood tests for diagnosis and monitoring. Electronic health records (EHRs) have emerged as valuable data sources for numerous medical studies. EHR-based hemoglobin…

Machine Learning · Computer Science 2024-01-23 Zhuo Zhi , Moe Elbadawi , Adam Daneshmend , Mine Orlu , Abdul Basit , Andreas Demosthenous , Miguel Rodrigues

Introduction: The blood-brain barrier (BBB) protects the central nervous system but prevents most neurotherapeutics from reaching effective concentrations in the brain. BBB-penetrating peptides (BBBPs) offer a promising strategy for brain…

Quantitative Methods · Quantitative Biology 2025-12-15 Kaijie Wang , Le Yin , Aodi Tian , Zhiqiang Wei , Zai Yang , Min Han , Qichun Wei , Sheng Wang

In this paper, an end-to-end nonlinear model reduction methodology is presented based on the convolutional recurrent autoencoder networks. The methodology is developed in the context of the overall data-driven reduced-order model framework…

Fluid Dynamics · Physics 2020-03-30 Sandeep Reddy Bukka , Allan Ross Magee , Rajeev Kumar Jaiman

Structural optimization is essential for designing safe, efficient, and durable components with minimal material usage. Traditional methods for vibration control often rely on active systems to mitigate unpredictable vibrations, which may…

Computational Physics · Physics 2024-12-31 A. Tollardo , F. Cadini , M. Giglio , L. Lomazzi

We report on a general and automatic data-driven background distribution shape estimation method using neural autoregressive flows (NAF), which is one of the deep generative learning methods. Data-driven background estimation is…

High Energy Physics - Phenomenology · Physics 2020-08-11 Suyong Choi , Jaehoon Lim , Hayoung Oh

Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide, yet early risk detection is often limited by available diagnostics. Carotid ultrasound, a non-invasive and widely accessible modality, encodes rich structural…

Automated blood vessel segmentation is vital for biomedical imaging, as vessel changes indicate many pathologies. Still, precise segmentation is difficult due to the complexity of vascular structures, anatomical variations across patients,…

Cardiovascular diseases (CVDs) are the number one cause of death worldwide. While there is growing evidence that the atrial fibrillation (AF) has strong associations with various CVDs, this heart arrhythmia is usually diagnosed using…

Systems and Control · Electrical Eng. & Systems 2022-07-13 Wei-Ying Yi , Peng-Fei Liu , Sheung-Lai Lo , Ya-Fen Chan , Yu Zhou , Yee Leung , Kam-Sang Woo , Alex Pui-Wai Lee , Jia-Min Chen , Kwong-Sak Leung

In this paper we introduce a novel Neural Networks-based approach for approximating solutions to the (2D) incompressible Navier--Stokes equations, which is an extension of so called Deep Random Vortex Methods (DRVM), that does not require…

Fluid Dynamics · Physics 2024-12-02 Vladislav Cherepanov , Sebastian W. Ertel

According to the World Health Organization, around 36% of the annual deaths are associated with cardiovascular diseases and 90% of heart attacks are preventable. Electrocardiogram signal analysis in ambulatory electrocardiography, during an…

Signal Processing · Electrical Eng. & Systems 2021-01-13 Francisco Perdigon Romero , David Castro Piñol , Carlos Román Vázquez Seisdedos

Respiration is a critical vital sign for infants, and continuous respiratory monitoring is particularly important for newborns. However, neonates are sensitive and contact-based sensors present challenges in comfort, hygiene, and skin…

Image and Video Processing · Electrical Eng. & Systems 2023-07-26 Sai Kumar Reddy Manne , Shaotong Zhu , Sarah Ostadabbas , Michael Wan

Coronary angiography remains the gold standard for diagnosing Acute Coronary Syndrome (ACS). However, its resource-intensive and invasive nature can expose patients to procedural risks and diagnostic delays, leading to postponed treatment…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Diane Kim , Minh Nguyen Nhat To , Sherif Abdalla , Teresa S. M. Tsang , Purang Abolmaesumi , and Christina Luong

Patient-specific modeling of cardiovascular flows with high-fidelity is challenging due to its dependence on accurately estimated velocity boundary profiles, which are essential for precise simulations and directly influence wall shear…

Numerical Analysis · Mathematics 2024-11-28 Kabir Bakhshaei , Sajad Salavatidezfouli , Giovanni Stabile , Gianluigi Rozza

Near-wall blood flow and wall shear stress (WSS) regulate major forms of cardiovascular disease, yet they are challenging to quantify with high fidelity. Patient-specific computational and experimental measurement of WSS suffers from…

Fluid Dynamics · Physics 2021-07-28 Amirhossein Arzani , Jian-Xun Wang , Roshan M. D'Souza

Cardiac arrhythmogenesis is governed by complex electromechanical interactions that are not directly observable in vivo, motivating the development of non-invasive computational approaches for reconstructing three-dimensional activation…

Medical Physics · Physics 2026-03-05 Nathan Dermul , Hans Dierckx

This study develops and validates neural network frameworks with physics-based constraints for surrogate modeling of rarefied gas dynamics across different levels of complexity. As a baseline, we first examine the BGK kinetic relaxation…

Fluid Dynamics · Physics 2025-09-09 Ehsan Roohi , Ahmad Shoja-Sani , Bijan Goshayeshi , Ahmad Peyvan

CFD is widely used in physical system design and optimization, where it is used to predict engineering quantities of interest, such as the lift on a plane wing or the drag on a motor vehicle. However, many systems of interest are…

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