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The general trace reconstruction problem seeks to recover an original sequence from its noisy copies independently corrupted by deletions, insertions, and substitutions. This problem arises in applications such as DNA data storage, a…

Machine Learning · Computer Science 2025-07-18 Franziska Weindel , Michael Girsch , Reinhard Heckel

We consider the problem of learning a linear factor model. We propose a regularized form of principal component analysis (PCA) and demonstrate through experiments with synthetic and real data the superiority of resulting estimates to those…

Machine Learning · Computer Science 2013-05-31 Yi-Hao Kao , Benjamin Van Roy

Causal theory is now widely developed with many applications to medicine and public health. However within the discipline of reliability, although causation is a key concept in this field, there has been much less theoretical attention. In…

Artificial Intelligence · Computer Science 2020-02-17 Xuewen Yu , Jim Q. Smith , Linda Nichols

Spectral deconvolution is essential for extracting peak structures that encode material properties and chemical structures, but conventional automated methods often fail when spectra contain high-intensity noise or unknown background…

Data Analysis, Statistics and Probability · Physics 2026-05-19 Hayato Okubo , Yoshifumi Amamoto , Toshimitsu Aritake , Hiroyuki Kumazoe , Shiryu Nakano , Evan Jamison , Satoshi Tanaka , Yoh-ichi Mototake

Theory refinement is the task of updating a domain theory in the light of new cases, to be done automatically or with some expert assistance. The problem of theory refinement under uncertainty is reviewed here in the context of Bayesian…

Artificial Intelligence · Computer Science 2013-03-26 Wray L. Buntine

Bayesian inference provides a natural way of incorporating prior beliefs and assigning a probability measure to the space of hypotheses. Current solutions rely on iterative routines like Markov Chain Monte Carlo (MCMC) sampling and…

Machine Learning · Computer Science 2025-02-11 Sarthak Mittal , Niels Leif Bracher , Guillaume Lajoie , Priyank Jaini , Marcus Brubaker

This paper presents a model-based, unsupervised algorithm for recovering word boundaries in a natural-language text from which they have been deleted. The algorithm is derived from a probability model of the source that generated the text.…

Computation and Language · Computer Science 2007-05-23 Michael R. Brent

Storytelling, whether via fables, news reports, documentaries, or memoirs, can be thought of as the communication of interesting and related events that, taken together, form a concrete process. It is desirable to extract the event chains…

Computation and Language · Computer Science 2021-09-23 Xiyang Zhang , Muhao Chen , Jonathan May

We are facing a real challenge when coping with the continuous acceleration of scientific production and the increasingly changing nature of science. In this article, we extend the classical framework of co-word analysis to the study of…

Physics and Society · Physics 2015-03-13 David Chavalarias , Jean-Philippe Cointet

Various graphical models are widely used in reliability to provide a qualitative description of domain experts hypotheses about how a system might fail. Here we argue that the semantics developed within standard causal Bayesian networks are…

Statistics Theory · Mathematics 2021-10-05 Xuewen Yu , Jim Q. Smith

We propose a statistical method to test whether two phylogenetic trees with given alignments are significantly incongruent. Our method compares the two distributions of phylogenetic trees given by the input alignments, instead of comparing…

Populations and Evolution · Quantitative Biology 2010-04-14 Elissaveta Arnaoudova , David Haws , Peter Huggins , Jerzy W. Jaromczyk , Neil Moore , Chris Schardl , Ruriko Yoshida

Modern explainable AI still struggles with a fundamental gap: although Bayesian networks (BNs) provide transparent probabilistic structure, there is no unified way to formally express, query, and verify what these models imply. Analysts…

Artificial Intelligence · Computer Science 2026-04-29 Stefano M. Nicoletti , E. Moritz Hahn , Mariëlle Stoelinga

Principal components analysis (PCA) is a classical method for the reduction of dimensionality of data in the form of n observations (or cases) of a vector with p variables. For a simple model of factor analysis type, it is proved that…

Statistics Theory · Mathematics 2009-01-29 Iain M Johnstone , Arthur Yu Lu

This paper investigates the knowledge of language models from the perspective of Bayesian epistemology. We explore how language models adjust their confidence and responses when presented with evidence with varying levels of informativeness…

Artificial Intelligence · Computer Science 2025-04-29 Minsu Kim , Sangryul Kim , James Thorne

In recent years, large language models (LLMs) have achieved state-of-the-art results in various biological sequence analysis tasks, such as sequence classification, structure prediction, and function prediction. Similar to advancements in…

Genomics · Quantitative Biology 2025-02-19 Wang Liang

Tree ensembles, such as random forests and boosted trees, are renowned for their high prediction performance. However, their interpretability is critically limited due to the enormous complexity. In this study, we present a method to make a…

Machine Learning · Statistics 2017-03-01 Satoshi Hara , Kohei Hayashi

Replication studies are essential for assessing the credibility of claims from original studies. A critical aspect of designing replication studies is determining their sample size; a too small sample size may lead to inconclusive studies…

Methodology · Statistics 2023-08-14 Samuel Pawel , Guido Consonni , Leonhard Held

Children learn their native language by exposure to their linguistic and communicative environment, but apparently without requiring that their mistakes are corrected. Such learning from positive evidence has been viewed as raising logical…

Computation and Language · Computer Science 2013-01-21 Anne S. Hsu , Nick Chater , Paul M. B. Vitányi

The analysis of the three-dimensional structure of proteins is an important topic in molecular biochemistry. Structure plays a critical role in defining the function of proteins and is more strongly conserved than amino acid sequence over…

Applications · Statistics 2015-01-19 Abel Rodriguez , Scott C. Schmidler

Determining the relative importance of the elements in a sentence is a key factor for effortless natural language understanding. For human language processing, we can approximate patterns of relative importance by measuring reading…

Computation and Language · Computer Science 2021-06-08 Nora Hollenstein , Lisa Beinborn