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Most biological data are multidimensional, posing a major challenge to human comprehension and computational analysis. Principal component analysis is the most popular approach to rendering two- or three-dimensional representations of the…

Methodology · Statistics 2016-09-13 Tom M. W. Nye , Xiaoxian Tang , Grady Weyenberg , Ruriko Yoshida

Phylogenetic analysis of DNA or other data commonly gives rise to a collection or sample of inferred evolutionary trees. Principal Components Analysis (PCA) cannot be applied directly to collections of trees since the space of evolutionary…

Statistics Theory · Mathematics 2012-02-24 Tom M. W. Nye

Bayesian inference is now a leading technique for reconstructing phylogenetic trees from aligned sequence data. In this short note, we formally show that the maximum posterior tree topology provides a statistically consistent estimate of a…

Populations and Evolution · Quantitative Biology 2013-07-12 Mike Steel

Evolution is a process that is influenced by various environmental factors, e.g. the interactions between different species, genes, and biogeographical properties. Hence, it is interesting to study the combined evolutionary history of…

Quantitative Methods · Quantitative Biology 2013-08-02 Nicolas Wieseke , Matthias Bernt , Martin Middendorf

We derive tractable criteria for the consistency of Bayesian tree reconstruction procedures, which constitute a central class of algorithms for inferring common ancestry among DNA sequence samples in phylogenetics. Our results encompass…

Statistics Theory · Mathematics 2025-08-05 Alisa Kirichenko , Luke J. Kelly , Jere Koskela

Parse trees are fundamental syntactic structures in both computational linguistics and compilers construction. We argue in this paper that, in both fields, there are good incentives for model-checking sets of parse trees for some word…

Logic in Computer Science · Computer Science 2013-08-23 Anudhyan Boral , Sylvain Schmitz

Historical linguistics aims at inferring the most likely language phylogenetic tree starting from information concerning the evolutionary relatedness of languages. The available information are typically lists of homologous (lexical,…

Physics and Society · Physics 2015-05-27 Simone Pompei , Vittorio Loreto , Francesca Tria

Most phylogenetic analyses result in a sample of trees, but summarizing and visualizing these samples can be challenging. Consensus trees often provide limited information about a sample, and so methods such as consensus networks,…

Populations and Evolution · Quantitative Biology 2014-09-03 Tom M. W. Nye

Phylogenetic trees describe the evolutionary history of a group of present-day species from a common ancestor. These trees are typically reconstructed from aligned DNA sequence data. In this paper we analytically address the following…

Populations and Evolution · Quantitative Biology 2008-07-14 Mike Steel , Laszlo Szekely , Elchanan Mossel

This article introduces a new signal analysis method, which can be interpreted as a principal component analysis in sparse decomposition of the signal. The method, called principal basis analysis, is based on a novel criterion:…

Computer Vision and Pattern Recognition · Computer Science 2015-11-26 Hong Sun , Cheng-Wei Sang , Chen-Guang Liu

Grounding natural language in images, such as localizing "the black dog on the left of the tree", is one of the core problems in artificial intelligence, as it needs to comprehend the fine-grained and compositional language space. However,…

Computer Vision and Pattern Recognition · Computer Science 2019-06-06 Richang Hong , Daqing Liu , Xiaoyu Mo , Xiangnan He , Hanwang Zhang

Principal component regression uses principal components as regressors. It is particularly useful in prediction settings with high-dimensional covariates. The existing literature treating of Bayesian approaches is relatively sparse. We…

Methodology · Statistics 2020-01-28 Philippe Gagnon , Mylène Bédard , Alain Desgagné

Lexical resemblances among a group of languages indicate that the languages could be genetically related, i.e., they could have descended from a common ancestral language. However, such resemblances can arise by chance and, hence, need not…

Computation and Language · Computer Science 2024-04-02 V. S. D. S. Mahesh Akavarapu , Arnab Bhattacharya

Phylogenetic trees elucidate evolutionary relationships among species, but phylogenetic inference remains challenging due to the complexity of combining continuous (branch lengths) and discrete parameters (tree topology). Traditional Markov…

Populations and Evolution · Quantitative Biology 2024-12-30 ChenRui Duan , Zelin Zang , Siyuan Li , Yongjie Xu , Stan Z. Li

The statistical analysis of tree structured data is a new topic in statistics with wide application areas. Some Principal Component Analysis (PCA) ideas were previously developed for binary tree spaces. In this study, we extend these ideas…

Methodology · Statistics 2012-02-14 Carlos A. Alfaro , Burcu Aydın , Elizabeth Bullitt , Alim Ladha , Carlos E. Valencia

In this paper, we propose a model for building natural language explanations for Bayesian Network Reasoning in terms of factor arguments, which are argumentation graphs of flowing evidence, relating the observed evidence to a target…

Artificial Intelligence · Computer Science 2024-10-24 Jaime Sevilla , Nikolay Babakov , Ehud Reiter , Alberto Bugarin

Principal component analysis is a widely-used method for the dimensionality reduction of a given data set in a high-dimensional Euclidean space. Here we define and analyze two analogues of principal component analysis in the setting of…

Combinatorics · Mathematics 2017-10-17 Ruriko Yoshida , Leon Zhang , Xu Zhang

Principal component analysis (PCA) is often used to analyze multivariate data together with cluster analysis, which depends on the number of principal components used. It is therefore important to determine the number of significant…

Applications · Statistics 2024-09-19 Joshua C. Macdonald , Javier Blanco-Portillo , Marcus W. Feldman , Yoav Ram

Phylogenetic reconstruction aims at finding plausible hypotheses of the evolutionary history of genes or species based on genomic sequence information. The distinction of orthologous genes (genes that having a common ancestry and diverged…

Populations and Evolution · Quantitative Biology 2016-02-29 Marc Hellmuth , Nicolas Wieseke

While modern biotechnologies allow synthesizing new proteins and function measurements at scale, efficiently exploring a protein sequence space and engineering it remains a daunting task due to the vast sequence space of any given protein.…

Biomolecules · Quantitative Biology 2024-01-15 Jiahao Qiu , Hui Yuan , Jinghong Zhang , Wentao Chen , Huazheng Wang , Mengdi Wang
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