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Continuous adaptation allows survival in an ever-changing world. Adjustments in the synaptic coupling strength between neurons are essential for this capability, setting us apart from simpler, hard-wired organisms. How these changes can be…

Neurons and Cognition · Quantitative Biology 2021-01-06 Jakob Jordan , Maximilian Schmidt , Walter Senn , Mihai A. Petrovici

Simulations are vital for understanding and predicting the evolution of complex molecular systems. However, despite advances in algorithms and special purpose hardware, accessing the timescales necessary to capture the structural evolution…

Computational Physics · Physics 2021-02-18 Pantelis R. Vlachas , Julija Zavadlav , Matej Praprotnik , Petros Koumoutsakos

We apply evolutionary reinforcement learning to a simulation model in order to identify efficient time-dependent erasure protocols for a physical realization of a one-bit memory by an underdamped mechanical cantilever. We show that these…

Statistical Mechanics · Physics 2025-05-13 Nicolas Barros , Stephen Whitelam , Sergio Ciliberto , Ludovic Bellon

Important classes of active matter systems can be modeled using kinetic theories. However, kinetic theories can be high dimensional and challenging to simulate. Reduced-order representations based on tracking only low-order moments of the…

Computational Physics · Physics 2023-08-15 Suryanarayana Maddu , Scott Weady , Michael J. Shelley

Understanding how complex systems respond to perturbations, such as whether they will remain stable or what their most sensitive patterns are, is a fundamental challenge across science and engineering. Traditional stability and receptivity…

Fluid Dynamics · Physics 2026-04-28 Chengyun Wang , Liwei Chen , Nils Thuerey

Neural population activity often exhibits regime-dependent non-stationarity in the form of switching dynamics. Learning accurate switching dynamical system models can reveal how behavior is encoded in neural activity. Existing switching…

Machine Learning · Computer Science 2025-12-16 DongKyu Kim , Han-Lin Hsieh , Maryam M. Shanechi

In many engineered systems, optimization is used for decision making at time-scales ranging from real-time operation to long-term planning. This process often involves solving similar optimization problems over and over again with slightly…

Optimization and Control · Mathematics 2019-01-18 Sidhant Misra , Line Roald , Yeesian Ng

Molecular dynamics simulations are an important tool for describing the evolution of a chemical system with time. However, these simulations are inherently held back either by the prohibitive cost of accurate electronic structure theory…

Chemical Physics · Physics 2018-12-20 Michael Gastegger , Philipp Marquetand

We demonstrate a machine learning based approach which can learn the time-dependent electronic excitation dynamics of small molecules subjected to ion irradiation. Ensembles of recurrent neural networks are trained on data generated by…

Chemical Physics · Physics 2024-09-24 Ethan P. Shapera , Cheng-Wei Lee

We implement a network-based approach to study expertise in a complex real-world task: operating particle accelerators. Most real-world tasks we learn and perform (e.g., driving cars, operating complex machines, solving mathematical…

Social and Information Networks · Computer Science 2024-12-25 Roussel Rahman , Jane Shtalenkova , Aashwin Ananda Mishra , Wan-Lin Hu

In this study, we present a graph neural network-based learning approach using an autoencoder setup to derive low-dimensional variables from features observed in experimental crystal structures. These variables are then biased in enhanced…

Statistical Mechanics · Physics 2023-10-13 Ziyue Zou , Pratyush Tiwary

Determining the different conformational states of a protein and the transition paths between them is key to fully understanding the relationship between biomolecular structure and function. This can be accomplished by sampling protein…

Biological Physics · Physics 2021-03-24 Venkata K. Ramaswamy , Chris G. Willcocks , Matteo T. Degiacomi

Complex environments provide structured yet variable sensory inputs. To best exploit information from these environments, organisms must evolve the ability to anticipate consequences of unknown stimuli, and act on these predictions. We…

Neural and Evolutionary Computing · Computer Science 2019-07-16 Lana Sinapayen , Atsushi Masumori , Ikegami Takashi

Quantum chemical simulations can be greatly accelerated by constructing machine learning potentials, which is often done using active learning (AL). The usefulness of the constructed potentials is often limited by the high effort required…

Chemical Physics · Physics 2024-09-19 Yi-Fan Hou , Lina Zhang , Quanhao Zhang , Fuchun Ge , Pavlo O. Dral

Recent experimental studies indicate that synaptic changes induced by neuronal activity are discrete jumps between a small number of stable states. Learning in systems with discrete synapses is known to be a computationally hard problem.…

Neurons and Cognition · Quantitative Biology 2009-11-13 Carlo Baldassi , Alfredo Braunstein , Nicolas Brunel , Riccardo Zecchina

Neural networks are able to extract information from the timing of spikes. Here we provide new results on the behavior of the simplest neuronal model which is able to decode information embedded in temporal spike patterns, the so called…

Disordered Systems and Neural Networks · Physics 2015-06-17 Carlo Baldassi , Alfredo Braunstein , Riccardo Zecchina

We develop a learning-based algorithm for the distributed formation control of networked multi-agent systems governed by unknown, nonlinear dynamics. Most existing algorithms either assume certain parametric forms for the unknown dynamic…

Systems and Control · Electrical Eng. & Systems 2022-07-19 Christos K. Verginis , Zhe Xu , Ufuk Topcu

This paper is concerned with the robust tracking control of linear uncertain systems, whose unknown system parameters and disturbances are bounded within ellipsoidal sets. We propose an adaptive robust control that can actively learn the…

Systems and Control · Electrical Eng. & Systems 2023-08-08 Xuehui Ma , Shiliang Zhang , Yushuai Li , Fucai Qian , Tingwen Huang

Controlled activity of active entities interacting with a passive environment can generate emergent system-level phenomena, positioning such systems as promising platforms for potential downstream applications in targeted drug delivery,…

Soft Condensed Matter · Physics 2025-10-07 Thomas Jacob , Siddhant Mohapatra , Rajalingam A , Sam Mathew , Pallab Sinha Mahapatra

The goal of this work is to train a neural network which approximates solutions to the Navier-Stokes equations across a region of parameter space, in which the parameters define physical properties such as domain shape and boundary…

Computational Physics · Physics 2021-06-02 Christopher J Arthurs , Andrew P King