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Patients have distinct information needs about their hospitalization that can be addressed using clinical evidence from electronic health records (EHRs). While artificial intelligence (AI) systems show promise in meeting these needs, robust…

Computation and Language · Computer Science 2026-03-31 Sarvesh Soni , Dina Demner-Fushman

Artificial intelligence has demonstrated significant potential in clinical decision-making; however, developing models capable of adapting to diverse real-world scenarios and performing complex diagnostic reasoning remains a major…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Ronghao Xu , Zhen Huang , Yangbo Wei , Xiaoqian Zhou , Zikang Xu , Ting Liu , Zihang Jiang , S. Kevin Zhou

Large language models (LLMs) have significantly advanced natural language understanding and demonstrated strong problem-solving abilities. Despite these successes, most LLMs still struggle with solving mathematical problems due to the…

Computation and Language · Computer Science 2024-06-27 Meng Fang , Xiangpeng Wan , Fei Lu , Fei Xing , Kai Zou

In recent years, Large Language Models (LLMs) have become widely used in medical applications, such as clinical decision support, medical education, and medical question answering. Yet, these models are often English-centric, limiting their…

Computation and Language · Computer Science 2026-02-06 Chaimae Abouzahir , Congbo Ma , Nizar Habash , Farah E. Shamout

Large language models (LLMs) are increasingly envisioned as decision-support tools in clinical practice, yet safe clinical reasoning demands integrating heterogeneous knowledge bases -- trials, primary studies, regulatory documents, and…

Computation and Language · Computer Science 2025-05-22 Shan Chen , Pedro Moreira , Yuxin Xiao , Sam Schmidgall , Jeremy Warner , Hugo Aerts , Thomas Hartvigsen , Jack Gallifant , Danielle S. Bitterman

Rapid integration of large language models (LLMs) in health care is sparking global discussion about their potential to revolutionize health care quality and accessibility. At a time when improving health care quality and access remains a…

Computers and Society · Computer Science 2025-04-01 Troy Zada , Natalie Tam , Francois Barnard , Marlize Van Sittert , Venkat Bhat , Sirisha Rambhatla

Although large language models (LLMs) often produce impressive outputs, it remains unclear how they perform in real-world scenarios requiring strong reasoning skills and expert domain knowledge. We set out to investigate whether close- and…

Computation and Language · Computer Science 2023-12-27 Valentin Liévin , Christoffer Egeberg Hother , Andreas Geert Motzfeldt , Ole Winther

Large language models (LLMs) have achieved strong performance on medical exam-style tasks, motivating growing interest in their deployment in real-world clinical settings. However, clinical decision-making is inherently safety-critical,…

Computation and Language · Computer Science 2026-04-13 Xiaohan Ren , Chenxiao Fan , Wenyin Ma , Hongliang He , Chongming Gao , Xiaoyan Zhao , Fuli Feng

Clinical Question Answering (QA) systems enable doctors to quickly access patient information from electronic health records (EHRs). However, training these systems requires significant annotated data, which is limited due to the expertise…

Computation and Language · Computer Science 2024-12-09 Fan Bai , Keith Harrigian , Joel Stremmel , Hamid Hassanzadeh , Ardavan Saeedi , Mark Dredze

This paper investigates the effectiveness of large language models (LLMs) in answering questions over datasets. We examine their performance in two scenarios: (a) directly answering questions given a dataset file as input, and (b)…

Computation and Language · Computer Science 2026-05-12 Andreas Xenofontos , Pavlos Fafalios

Integrating large language models (LLMs) like DeepSeek R1 into healthcare requires rigorous evaluation of their reasoning alignment with clinical expertise. This study assesses DeepSeek R1's medical reasoning against expert patterns using…

Computation and Language · Computer Science 2025-04-02 Birger Moell , Fredrik Sand Aronsson , Sanian Akbar

This study presents a systematic approach to identifying and characterizing student misconceptions in online learning environments through a novel combination of quantitative performance analysis and large language model (LLM) assessment.…

Computation and Language · Computer Science 2026-05-04 Michael J. Parker , Maria G. Zavala-Cerna

Large language models (LLMs) demonstrate remarkable performance across various tasks, prompting researchers to develop diverse evaluation benchmarks. However, most benchmarks typically measure the ability of LLMs to respond to individual…

Computation and Language · Computer Science 2026-01-30 Yutao Hou , Yajing Luo , Zhiwen Ruan , Hongru Wang , Weifeng Ge , Yun Chen , Guanhua Chen

Multimodal Large Language Models (MLLMs) have demonstrated impressive abilities across various tasks, including visual question answering and chart comprehension, yet existing benchmarks for chart-related tasks fall short in capturing the…

Computation and Language · Computer Science 2025-02-11 Zifeng Zhu , Mengzhao Jia , Zhihan Zhang , Lang Li , Meng Jiang

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

Generative large language models (LLMs) have shown great success in various applications, including question-answering (QA) and dialogue systems. However, in specialized domains like traditional Chinese medical QA, these models may perform…

Computation and Language · Computer Science 2023-09-06 Yang Tan , Mingchen Li , Zijie Huang , Huiqun Yu , Guisheng Fan

While Large Language Models (LLMs) achieve near-human performance on standard benchmarks, their capabilities often fail to generalize to complex, real-world problems. To bridge this gap, we introduce DeepQuestion, a scalable, automated…

Computation and Language · Computer Science 2026-03-02 Ali Khoramfar , Ali Ramezani , Mohammad Mahdi Mohajeri , Mohammad Javad Dousti , Majid Nili Ahmadabadi , Heshaam Faili

Medical large language models (LLMs) research often makes bold claims, from encoding clinical knowledge to reasoning like a physician. These claims are usually backed by evaluation on competitive benchmarks; a tradition inherited from…

Computation and Language · Computer Science 2025-03-17 Ahmed Alaa , Thomas Hartvigsen , Niloufar Golchini , Shiladitya Dutta , Frances Dean , Inioluwa Deborah Raji , Travis Zack

Large Language Models (LLMs) achieve competitive results compared to human experts in medical examinations. However, it remains a challenge to apply LLMs to complex clinical decision-making, which requires a deep understanding of medical…

As Large Language Models (LLMs) advance, their potential for widespread societal impact grows simultaneously. Hence, rigorous LLM evaluations are both a technical necessity and social imperative. While numerous evaluation benchmarks have…

Computation and Language · Computer Science 2025-04-22 Jaime Raldua Veuthey , Zainab Ali Majid , Suhas Hariharan , Jacob Haimes