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Phenotypic characterization is essential for understanding heterogeneity in chronic diseases and for guiding personalized interventions. Long COVID, a complex and persistent condition, yet its clinical subphenotypes remain poorly…

Machine Learning · Computer Science 2026-03-20 Jing Wang , Jie Shen , Amar Sra , Qiaomin Xie , Jeremy C Weiss

Timely prediction of clinically critical events in Intensive Care Unit (ICU) is important for improving care and survival rate. Most of the existing approaches are based on the application of various classification methods on explicitly…

Computer Vision and Pattern Recognition · Computer Science 2018-12-05 Jwala Dhamala , Emmanuel Azuh , Abdullah Al-Dujaili , Jonathan Rubin , Una-May O'Reilly

We present a novel application of LSTM recurrent neural networks to multilabel classification of diagnoses given variable-length time series of clinical measurements. Our method outperforms a strong baseline on a variety of metrics.

Machine Learning · Computer Science 2017-03-23 Zachary C. Lipton , David C. Kale , Randall C. Wetzel

Medical time series are often irregular and face significant missingness, posing challenges for data analysis and clinical decision-making. Existing methods typically adopt a single modeling perspective, either treating series data as…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Liuqing Chen , Shuhong Xiao , Shixian Ding , Shanhai Hu , Lingyun Sun

The rapid global aging trend has led to an increase in dementia cases, including Alzheimer's disease, underscoring the urgent need for early and accurate diagnostic methods. Traditional diagnostic techniques, such as cognitive tests,…

Machine Learning · Computer Science 2024-09-06 Juan A. Berrios Moya

Longitudinal biomedical studies play a vital role in tracking disease progression, treatment response, and the emergence of resistance mechanisms, particularly in complex disorders such as cancer and neurodegenerative diseases. However, the…

Quantitative Methods · Quantitative Biology 2025-04-28 Maria Demidik , Filippo Utro , Alexey Galda , Karl Jansen , Daniel Blankenberg , Laxmi Parida

Joint models (JMs) for longitudinal and time-to-event data are an important class of biostatistical models in health and medical research. When the study population consists of heterogeneous subgroups, the standard JM may be inadequate and…

Methodology · Statistics 2024-10-31 Sida Chen , Danilo Alvares , Marco Palma , Jessica K. Barrett

Advanced by rich perception and precise execution, robots possess immense potential to provide professional and customized rehabilitation exercises for patients with mobility impairments caused by strokes. Autonomous robotic rehabilitation…

Robotics · Computer Science 2024-03-11 Xinyu Jiang , Yibei Guo , Mengsha Hu , Ruoming Jin , Hai Phan , Jay Alberts , Rui Liu

Introduction Quantum Convolutional Neural Network (QCNN)-Long Short-Term Memory (LSTM) models were studied to provide sequential relationships for each timepoint in MRIs of patients with Multiple Sclerosis (MS). In this pilot study, we…

Machine Learning · Computer Science 2024-01-23 John D. Mayfield , Issam El Naqa

The COVID-19 pandemic has had a considerable impact on day-to-day life. Tackling the disease by providing the necessary resources to the affected is of paramount importance. However, estimation of the required resources is not a trivial…

Image and Video Processing · Electrical Eng. & Systems 2022-05-11 Sai Vidyaranya Nuthalapati , Marcela Vizcaychipi , Pallav Shah , Piotr Chudzik , Chee Hau Leow , Paria Yousefi , Ahmed Selim , Keiran Tait , Ben Irving

Machine learning is used in medicine to support physicians in examination, diagnosis, and predicting outcomes. One of the most dynamic area is the usage of patient generated health data from intensive care units. The goal of this paper is…

Intensive care unit (ICU) data are highly irregular, heterogeneous, and temporally fragmented, posing challenges for generalizable clinical prediction. We present PULSE-ICU, a self-supervised foundation model that learns event-level ICU…

Machine Learning · Computer Science 2025-12-01 Sejeong Jang , Joo Heung Yoon , Hyo Kyung Lee

Continual learning is essential for medical image classification systems to adapt to dynamically evolving clinical environments. The integration of multimodal information can significantly enhance continual learning of image classes.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Jiantao Tan , Peixian Ma , Kanghao Chen , Zhiming Dai , Ruixuan Wang

Monitoring physiological responses to hemodynamic stress can help in determining appropriate treatment and ensuring good patient outcomes. Physicians' intuition suggests that the human body has a number of physiological response patterns to…

Machine Learning · Computer Science 2019-11-14 Chufan Gao , Fabian Falck , Mononito Goswami , Anthony Wertz , Michael R. Pinsky , Artur Dubrawski

The increasing global prevalence of mental disorders, such as depression and PTSD, requires objective and scalable diagnostic tools. Traditional clinical assessments often face limitations in accessibility, objectivity, and consistency.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-03 Abdelrahaman A. Hassan , Abdelrahman A. Ali , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda

Brain functional connectivity (FC) extracted from resting-state fMRI (RS-fMRI) has become a popular approach for disease diagnosis, where discriminating subjects with mild cognitive impairment (MCI) from normal controls (NC) is still one of…

Computer Vision and Pattern Recognition · Computer Science 2018-08-31 Weizheng Yan , Han Zhang , Jing Sui , Dinggang Shen

A deep latent variable model is a powerful method for capturing complex distributions. These models assume that underlying structures, but unobserved, are present within the data. In this dissertation, we explore high-dimensional problems…

Machine Learning · Computer Science 2024-06-13 Khuong Vo

Machine Learning (ML) algorithms are generally designed for scenarios in which all data is stored in one data center, where the training is performed. However, in many applications, e.g., in the healthcare domain, the training data is…

Machine Learning · Computer Science 2024-09-16 Amin Aminifar , Matin Shokri , Amir Aminifar

Classification and segmentation are crucial in medical image analysis as they enable accurate diagnosis and disease monitoring. However, current methods often prioritize the mutual learning features and shared model parameters, while…

Computer Vision and Pattern Recognition · Computer Science 2023-08-03 Kai Ren , Ke Zou , Xianjie Liu , Yidi Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

Respiration rate (RR) is an important vital sign for clinical monitoring of hospitalized patients, with changes in RR being strongly tied to changes in clinical status leading to adverse events. Human labels for RR, based on counting…

Signal Processing · Electrical Eng. & Systems 2025-08-25 Thomas Kite , Brian Ayers , Nicholas Houstis , Asishana A. Osho , Thoralf M. Sundt , Aaron D Aguirre
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