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The escalating prevalence of cannabis use poses a significant public health challenge globally. In the U.S., cannabis use is more prevalent among emerging adults (EAs) (ages 18-25) than any other age group, with legalization in the multiple…

Machine Learning · Computer Science 2024-08-28 Susobhan Ghosh , Yongyi Guo , Pei-Yao Hung , Lara Coughlin , Erin Bonar , Inbal Nahum-Shani , Maureen Walton , Susan Murphy

Mobile health leverages personalized and contextually tailored interventions optimized through bandit and reinforcement learning algorithms. In practice, however, challenges such as participant heterogeneity, nonstationarity, and nonlinear…

Background: Cannabis use disorder (CUD) is a growing public health problem. Early identification of adolescents and young adults at risk of developing CUD in the future may help stem this trend. A logistic regression model fitted using a…

Introduction: Substance use disorders (SUDs) have emerged as a pressing public health concern in the United States, with adolescent substance use often leading to SUDs in adulthood. Effective strategies are needed to stem this progression.…

Applications · Statistics 2025-05-29 Tingfang Wang , Joseph M. Boden , Swati Biswas , Pankaj K. Choudhary

Wearable sensor systems have demonstrated a great potential for real-time, objective monitoring of physiological health to support behavioral interventions. However, obtaining accurate labels in free-living environments remains difficult…

Time-constrained decision processes have been ubiquitous in many fundamental applications in physics, biology and computer science. Recently, restart strategies have gained significant attention for boosting the efficiency of…

Machine Learning · Computer Science 2020-07-02 Semih Cayci , Atilla Eryilmaz , R. Srikant

Users can be supported to adopt healthy behaviors, such as regular physical activity, via relevant and timely suggestions on their mobile devices. Recently, reinforcement learning algorithms have been found to be effective for learning the…

Machine Learning · Computer Science 2020-12-23 Marianne Menictas , Sabina Tomkins , Susan Murphy

Offline reinforcement learning (RL) is challenged by the distributional shift between learning policies and datasets. To address this problem, existing works mainly focus on designing sophisticated algorithms to explicitly or implicitly…

Machine Learning · Computer Science 2022-10-18 Yang Yue , Bingyi Kang , Xiao Ma , Zhongwen Xu , Gao Huang , Shuicheng Yan

Reinforcement learning (RL) has emerged as a promising strategy for finetuning small language models (SLMs) to solve targeted tasks such as math and coding. However, RL algorithms tend to be resource-intensive, taking a significant amount…

Machine Learning · Computer Science 2025-10-07 Lianghuan Huang , Sagnik Anupam , Insup Lee , Shuo Li , Osbert Bastani

Older adults commonly experience chronic conditions such as pain and sleep disturbances and may consider cannabidiol for symptom management. Safe use requires appropriate dosing, careful titration, and awareness of drug interactions, yet…

Information Retrieval · Computer Science 2026-04-14 Ali Abedi , Charlene H. Chu , Shehroz S. Khan

The primary goal of my Ph.D. study is to develop provably efficient and practical algorithms for data-driven sequential decision-making under uncertainty. My work focuses on reinforcement learning (RL), multi-armed bandits, and their…

Machine Learning · Computer Science 2025-05-16 Zhiyong Wang

Dental disease is one of the most common chronic diseases despite being largely preventable. However, professional advice on optimal oral hygiene practices is often forgotten or abandoned by patients. Therefore patients may benefit from…

Artificial Intelligence · Computer Science 2022-09-15 Anna L. Trella , Kelly W. Zhang , Inbal Nahum-Shani , Vivek Shetty , Finale Doshi-Velez , Susan A. Murphy

Clinical trials involving multiple treatments utilize randomization of the treatment assignments to enable the evaluation of treatment efficacies in an unbiased manner. Such evaluation is performed in post hoc studies that usually use…

Artificial Intelligence · Computer Science 2018-09-10 Yogatheesan Varatharajah , Brent Berry , Sanmi Koyejo , Ravishankar Iyer

Most algorithms for the multi-armed bandit problem in reinforcement learning aimed to maximize the expected reward, which are thus useful in searching the optimized candidate with the highest reward (function value) for diverse applications…

Machine Learning · Computer Science 2022-01-03 Bin Chong , Yingguang Yang , Zi-Le Wang , Hang Xing , Zhirong Liu

Contextual bandit algorithms are commonly used in digital health to recommend personalized treatments. However, to ensure the effectiveness of the treatments, patients are often requested to take actions that have no immediate benefit to…

Machine Learning · Computer Science 2024-03-14 Kyra Gan , Esmaeil Keyvanshokooh , Xueqing Liu , Susan Murphy

Mobile health aims to enhance health outcomes by delivering interventions to individuals as they go about their daily life. The involvement of care partners and social support networks often proves crucial in helping individuals managing…

Machine Learning · Computer Science 2024-08-13 Shuangning Li , Lluis Salvat Niell , Sung Won Choi , Inbal Nahum-Shani , Guy Shani , Susan Murphy

Opioid use disorder (OUD) is a chronic and relapsing condition that involves the continued and compulsive use of opioids despite harmful consequences. The development of medications with improved efficacy and safety profiles for OUD…

Biomolecules · Quantitative Biology 2023-03-02 Hongsong Feng , Jian Jiang , Guo-Wei Wei

We consider the actor-critic contextual bandit for the mobile health (mHealth) intervention. State-of-the-art decision-making algorithms generally ignore the outliers in the dataset. In this paper, we propose a novel robust contextual…

Machine Learning · Computer Science 2018-02-28 Feiyun Zhu , Jun Guo , Ruoyu Li , Junzhou Huang

Public health practitioners often have the goal of monitoring patients and maximizing patients' time spent in "favorable" or healthy states while being constrained to using limited resources. Restless multi-armed bandits (RMAB) are an…

Machine Learning · Computer Science 2024-12-12 Gauri Jain , Pradeep Varakantham , Haifeng Xu , Aparna Taneja , Prashant Doshi , Milind Tambe

Delivering treatment recommendations via pervasive electronic devices such as mobile phones has the potential to be a viable and scalable treatment medium for long-term health behavior management. But active experimentation of treatment…

Information Retrieval · Computer Science 2020-08-24 Mawulolo K. Ameko , Miranda L. Beltzer , Lihua Cai , Mehdi Boukhechba , Bethany A. Teachman , Laura E. Barnes
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