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Foundation models have become a promising paradigm for advancing medical image analysis, particularly for segmentation tasks where downstream applications often emerge sequentially. Existing fine-tuning strategies, however, remain limited:…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Yiwen Ye , Yicheng Wu , Xiangde Luo , He Zhang , Ziyang Chen , Ting Dang , Yanning Zhang , Yong Xia

Clinical event sequences consist of thousands of clinical events that represent records of patient care in time. Developing accurate prediction models for such sequences is of a great importance for defining representations of a patient…

Machine Learning · Computer Science 2021-04-07 Jeong Min Lee , Milos Hauskrecht

Epidemic models are powerful tools in understanding infectious disease. However, as they increase in size and complexity, they can quickly become computationally intractable. Recent progress in modelling methodology has shown that surrogate…

Machine Learning · Computer Science 2023-03-13 Giovanni Charles , Timothy M. Wolock , Peter Winskill , Azra Ghani , Samir Bhatt , Seth Flaxman

Exponential growth in Electronic Healthcare Records (EHR) has resulted in new opportunities and urgent needs for discovery of meaningful data-driven representations and patterns of diseases in Computational Phenotyping research. Deep…

Machine Learning · Statistics 2015-12-14 Zhengping Che , Sanjay Purushotham , Robinder Khemani , Yan Liu

Modeling policies for sequential clinical decision-making based on observational data is useful for describing treatment practices, standardizing frequent patterns in treatment, and evaluating alternative policies. For each task, it is…

Machine Learning · Computer Science 2024-12-12 Anton Matsson , Lena Stempfle , Yaochen Rao , Zachary R. Margolin , Heather J. Litman , Fredrik D. Johansson

While pioneering deep learning methods have made great strides in analyzing electronic health record (EHR) data, they often struggle to fully capture the semantics of diverse medical codes from limited data. The integration of external…

Machine Learning · Computer Science 2024-08-26 Zhihao Yu , Yujie Jin , Yongxin Xu , Xu Chu , Yasha Wang , Junfeng Zhao

In this work, we introduce the Multiple Embedding Model for EHR (MEME), an approach that serializes multimodal EHR tabular data into text using pseudo-notes, mimicking clinical text generation. This conversion not only preserves better…

Computation and Language · Computer Science 2025-07-08 Simon A. Lee , Sujay Jain , Alex Chen , Kyoka Ono , Jennifer Fang , Akos Rudas , Jeffrey N. Chiang

Clinical decision support systems require models that are not only highly accurate but also equitable and sensitive to the implications of missed diagnoses. In this study, we introduce a knowledge-guided in-context learning (ICL) framework…

Machine Learning · Computer Science 2025-07-28 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia , Eugenio di Sciascio

Foundation models have emerged as a powerful approach for processing electronic health records (EHRs), offering flexibility to handle diverse medical data modalities. In this study, we present a comprehensive benchmark that evaluates the…

Machine Learning · Computer Science 2025-07-22 Kunyu Yu , Rui Yang , Jingchi Liao , Siqi Li , Huitao Li , Irene Li , Yifan Peng , Rishikesan Kamaleswaran , Nan Liu

Sepsis, a life-threatening inflammatory response to infection, causes organ dysfunction, making early detection and optimal management critical. Previous reinforcement learning (RL) approaches to sepsis management rely primarily on…

Machine Learning · Computer Science 2025-08-12 Yooseok Lim , ByoungJun Jeon , Seong-A Park , Jisoo Lee , Sae Won Choi , Chang Wook Jeong , Ho-Geol Ryu , Hongyeol Lee , Hyun-Lim Yang

This study introduces a pioneering Dynamic Hypergraph Networks (DHCE) model designed to predict future medical diagnoses from electronic health records with enhanced accuracy. The DHCE model innovates by identifying and differentiating…

Machine Learning · Computer Science 2025-01-07 Wangying Yang , Zitao Zheng , Zhizhong Wu , Bo Zhang , Yuanfang Yang

Time series data are prevalent in electronic health records, mostly in the form of physiological parameters such as vital signs and lab tests. The patterns of these values may be significant indicators of patients' clinical states and there…

Machine Learning · Computer Science 2019-11-18 Kun Zhang , Yuan Xue , Gerardo Flores , Alvin Rajkomar , Claire Cui , Andrew M. Dai

We present an automatic mortality prediction scheme based on the unstructured textual content of clinical notes. Proposing a convolutional document embedding approach, our empirical investigation using the MIMIC-III intensive care database…

Computation and Language · Computer Science 2016-12-05 Paulina Grnarova , Florian Schmidt , Stephanie L. Hyland , Carsten Eickhoff

Sequential pattern mining algorithms are widely used to explore care pathways database, but they generate a deluge of patterns, mostly redundant or useless. Clinicians need tools to express complex mining queries in order to generate less…

Artificial Intelligence · Computer Science 2017-07-27 Thomas Guyet , André Happe , Yann Dauxais

Research on emergency and mass casualty incident (MCI) triage has been limited by the absence of openly usable, reproducible benchmarks. Yet these scenarios demand rapid identification of the patients most in need, where accurate…

Machine Learning · Computer Science 2026-03-31 Joshua Sebastian , Karma Tobden , KMA Solaiman

The emergence of scaling laws has profoundly shaped the development of large language models (LLMs), enabling predictable performance gains through systematic increases in model size, dataset volume, and compute. Yet, these principles…

Computation and Language · Computer Science 2025-08-14 Sheng Zhang , Qin Liu , Naoto Usuyama , Cliff Wong , Tristan Naumann , Hoifung Poon

Health management has become a primary problem as new kinds of diseases and complex symptoms are introduced to a rapidly growing modern society. Building a better and smarter healthcare infrastructure is one of the ultimate goals of a smart…

Machine Learning · Computer Science 2025-03-24 Chu Myaet Thwal , Kyi Thar , Ye Lin Tun , Choong Seon Hong

We investigate the use of sequence analysis for behavior modeling, emphasizing that sequential context often outweighs the value of aggregate features in understanding human behavior. We discuss framing common problems in fields like…

Machine Learning · Computer Science 2024-11-06 Maxime Kawawa-Beaudan , Srijan Sood , Soham Palande , Ganapathy Mani , Tucker Balch , Manuela Veloso

Clinical outcome prediction based on the Electronic Health Record (EHR) plays a crucial role in improving the quality of healthcare. Conventional deep sequential models fail to capture the rich temporal patterns encoded in the longand…

Machine Learning · Computer Science 2019-08-27 Luchen Liu , Haoran Li , Zhiting Hu , Haoran Shi , Zichang Wang , Jian Tang , Ming Zhang

Rapid growth of the biomedical literature has led to many advances in the biomedical text mining field. Among the vast amount of information, biomedical article abstracts are the easily accessible sources. However, the number of the…

Computation and Language · Computer Science 2022-01-19 Mehmet Efruz Karabulut , K. Vijay-Shanker
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