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Deep Reinforcement Learning (DRL) is emerging as a promising approach to generate adaptive behaviors for robotic platforms. However, a major drawback of using DRL is the data-hungry training regime that requires millions of trial and error…

Feature selection prepares the AI-readiness of data by eliminating redundant features. Prior research falls into two primary categories: i) Supervised Feature Selection, which identifies the optimal feature subset based on their relevance…

Machine Learning · Computer Science 2024-03-08 Xinyuan Wang , Dongjie Wang , Wangyang Ying , Rui Xie , Haifeng Chen , Yanjie Fu

Controlling false discovery rate (FDR) while leveraging the side information of multiple hypothesis testing is an emerging research topic in modern data science. Existing methods rely on the test-level covariates while ignoring possible…

Machine Learning · Statistics 2021-01-26 Lin Qiu , Nils Murrugarra-Llerena , Vítor Silva , Lin Lin , Vernon M. Chinchilli

Variable selection plays a crucial role in enhancing modeling effectiveness across diverse fields, addressing the challenges posed by high-dimensional datasets of correlated variables. This work introduces a novel approach namely Knockoff…

Machine Learning · Statistics 2025-01-31 Xiaochen Zhang , Yunfeng Cai , Haoyi Xiong

In convolutional neural network (CNN), dropout cannot work well because dropped information is not entirely obscured in convolutional layers where features are correlated spatially. Except randomly discarding regions or channels, many…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Tianshu Xie , Minghui Liu , Jiali Deng , Xuan Cheng , Xiaomin Wang , Ming Liu

Voxel-based multiple testing is widely used in neuroimaging data analysis. Traditional false discovery rate (FDR) control methods often ignore the spatial dependence among the voxel-based tests and thus suffer from substantial loss of…

Machine Learning · Statistics 2024-05-06 Taehyo Kim , Hai Shu , Qiran Jia , Mony J. de Leon

In many applications, we need to study a linear regression model that consists of a response variable and a large number of potential explanatory variables and determine which variables are truly associated with the response. In 2015,…

Methodology · Statistics 2019-07-23 Jiajie Chen , Anthony Hou , Thomas Y. Hou

False discovery rate (FDR) is a cornerstone of modern multiple testing. However, it often fails to guarantee the reliability of "marginal" discoveries that lie at the boundary of the rejection set, which are often crucial in high-precision…

Methodology · Statistics 2026-05-12 Yifan Zhang , Wentao Zhang , Changliang Zou , Haojie Ren

In high-dimensional data analysis, such as financial index tracking or biomedical applications, it is crucial to select the few relevant variables while maintaining control over the false discovery rate (FDR). In these applications, strong…

Portfolio Management · Quantitative Finance 2024-01-31 Jasin Machkour , Daniel P. Palomar , Michael Muma

Genomic data are subject to various sources of confounding, such as demographic variables, biological heterogeneity, and batch effects. To identify genomic features associated with a variable of interest in the presence of confounders, the…

Methodology · Statistics 2025-12-08 Asmita Roy , Jun Chen , Xianyang Zhang

Genomics biobanks are information treasure troves with thousands of phenotypes (e.g., diseases, traits) and millions of single nucleotide polymorphisms (SNPs). The development of methodologies that provide reproducible discoveries is…

Methodology · Statistics 2024-10-08 Jasin Machkour , Michael Muma , Daniel P. Palomar

In many multiple testing applications in genetics, the signs of test statistics provide useful directional information, such as whether genes are potentially up- or down-regulated between two experimental conditions. However, most existing…

Methodology · Statistics 2025-07-22 Zhaoyang Tian , Kun Liang , Pengfei Li

The goal of feature selection is to identify important features that are relevant to explain an outcome variable. Most of the work in this domain has focused on identifying globally relevant features, which are features that are related to…

Machine Learning · Statistics 2019-05-30 Jaime Roquero Gimenez , James Zou

Deep neural networks (DNNs) have been widely criticized for their overconfidence when dealing with out-of-distribution (OOD) samples, highlighting the critical need for effective OOD detection to ensure the safe deployment of DNNs in…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 Zhiwei Ling , Yachen Chang , Hailiang Zhao , Xinkui Zhao , Kingsum Chow , Shuiguang Deng

Conditional independence testing (CIT) is essential for reliable scientific discovery. It prevents spurious findings and enables controlled feature selection. Recent CIT methods have used machine learning (ML) models as surrogates of the…

Statistics Theory · Mathematics 2026-02-02 Angel Reyero-Lobo , Bertrand Thirion , Pierre Neuvial

Balancing false discovery rate (FDR) control with high statistical power remains a central challenge in high-dimensional variable selection. While several FDR-controlling methods have been proposed, many degrade the original data -- by…

Methodology · Statistics 2025-07-16 Changhu Wang , Ziheng Zhang , Jingyi Jessica Li

The big breakthrough on the ImageNet challenge in 2012 was partially due to the `dropout' technique used to avoid overfitting. Here, we introduce a new approach called `Spectral Dropout' to improve the generalization ability of deep neural…

Computer Vision and Pattern Recognition · Computer Science 2017-11-27 Salman Khan , Munawar Hayat , Fatih Porikli

Deep neural networks have become the default choice for many of the machine learning tasks such as classification and regression. Dropout, a method commonly used to improve the convergence of deep neural networks, generates an ensemble of…

Machine Learning · Statistics 2019-04-11 Tal Kachman , Michal Moshkovitz , Michal Rosen-Zvi

Identifying truly predictive covariates while strictly controlling false discoveries remains a fundamental challenge in nonlinear, highly correlated, and low signal-to-noise regimes, where deep learning based feature selection methods are…

Machine Learning · Computer Science 2026-02-03 Bob Junyi Zou , Lu Tian

Dropout has been witnessed with great success in training deep neural networks by independently zeroing out the outputs of neurons at random. It has also received a surge of interest for shallow learning, e.g., logistic regression. However,…

Machine Learning · Computer Science 2016-12-06 Zhe Li , Boqing Gong , Tianbao Yang
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