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The present work presents a density-functional microscopic model of soft biological tissue. The model was based on a prototype molecular structure from experimentally resolved collagen peptide residues and water clusters and has the…
Silicone is frequently used as a model system to investigate and tune wetting on soft materials. Silicone is biocompatible and shows excellent thermal, chemical, and UV stability. Moreover, the mechanical properties of the surface can be…
In osteochondral tissue engineering (OCTE), simultaneously regenerating subchondral bone and cartilage tissue presents a significant challenge. Multiphasic scaffolds were created and manufactured using 3D printing to address this issue.…
Stimulus-responsive DNA-hydrogels with swelling capabilities are a promising class of materials for biomedical applications such as drug delivery and biosensing. However, translation of these systems to microscale applications requires…
This feature article considers the analysis of the initial states of film growth on polymer substrates. The assembled results are based on the cooperation between research groups in the field of plasma physics, chemistry, electric as well…
Accuracy in the measurement of mechanical properties is essential for precision engineering and for the interrogation of composition-property relationships. Conventional methods of mechanical testing, such as uniaxial tension, compression,…
Scaffolds have a key role in the clinical success of tissue engineering for the regeneration of damaged tissues. Their bio-performance is often described as the extent to which they can provide an extracellular matrix-like environment for…
We developed functional surfaces of laser-microstructured silicon coated with blends of polystyrene (PS) and poly(N-isopropylacrylamide) (PNIPAM) and we study their switching wetting behavior between hydrophilicity and hydrophobicity. Large…
For a tailored functionalization of cellulose based papers, the interaction between paper fibers and functional additives have to be understood. Planar cellulose surfaces present a suitable model system for studying the binding of…
Here, we present surface analysis and biocompatibility evaluation of novel composite material based on graphene oxide traded as Hastalex. First, the surface morphology and elemental analysis of the pristine material were examined by atomic…
Durable interfacing of hard and soft materials is a major design challenge caused by the ensuing stress concentrations. In nature, soft-hard interfaces exhibit remarkable mechanical performance, with failures rarely happening at the…
In this paper, we derive an effective macroscale description suitable to describe the growth of biological tissue within a porous tissue-engineering scaffold. As in our recent work (Holden \textit{et al.} "A multiphase multiscale model for…
This paper presents an experimental investigation on pattern formation and evolution in bilayered tubular organs using swelling deformation of polydimethylsiloxane (PDMS) and aims at supplying a thorough comparison with theoretical and…
Cells are known to sense and respond to their mechanical microenvironment in profound ways. Various evidence has implicated the adhesome, a body of adhesion associated proteins, in several cell fate decisions, including differentiation and…
Robotic stacking of van der Waals heterostructures has been at the verge thanks to the convergence between artificial intelligence (AI) and two-dimensional (2D) materials research. Key ingredients to fulfill this pursuit often include…
Effective scaffolds for bone tissue-engineering are those that combine adequate mechanical and chemical performance with osseointegrative, angiogenetic and anti-bacterial modes of bioactivity. To address these requirements via a combined…
The mesoscopic modeling of three polysiloxanes in solution is reported in this work, with the purpose of predicting their physicochemical properties as functions of the quality of the solvent, so that a judicious choice of polymer/solvent…
Mesoscale molecular assemblies on the cell surface, such as cilia and filopodia, integrate information, control transport and amplify signals. Synthetic devices mimicking these structures could sensitively monitor these cellular functions…
Polydimethylsiloxane (PDMS) microfluidic devices have become a standard tool for engineering cells and multicellular networks in vitro. However, the reservoirs, or through-holes where cells access the devices, are usually fabricated…
The ability to engineer localized surface plasmon resonances at large scale usually relies on precise nanoscale patterning. Here, we demonstrate that mid-infrared plasmonic responses can instead emerge in unpatterned polysilicon films…