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Language Models such as BERT have grown in popularity due to their ability to be pre-trained and perform robustly on a wide range of Natural Language Processing tasks. Often seen as an evolution over traditional word embedding techniques,…

Computation and Language · Computer Science 2022-06-30 Nimesh Bhana , Terence L. van Zyl

We introduce DNABERT-S, a tailored genome model that develops species-aware embeddings to naturally cluster and segregate DNA sequences of different species in the embedding space. Differentiating species from genomic sequences (i.e., DNA…

Genomics · Quantitative Biology 2024-10-23 Zhihan Zhou , Weimin Wu , Harrison Ho , Jiayi Wang , Lizhen Shi , Ramana V Davuluri , Zhong Wang , Han Liu

Masked Language Modeling (MLM) is widely used to pretrain language models. The standard random masking strategy in MLM causes the pre-trained language models (PLMs) to be biased toward high-frequency tokens. Representation learning of rare…

Computation and Language · Computer Science 2023-05-25 Linhan Zhang , Qian Chen , Wen Wang , Chong Deng , Xin Cao , Kongzhang Hao , Yuxin Jiang , Wei Wang

Integrating multi-omics data, such as DNA methylation, mRNA expression, and microRNA (miRNA) expression, offers a comprehensive view of the biological mechanisms underlying disease. However, the high dimensionality of multi-omics data, the…

Machine Learning · Computer Science 2026-02-12 Tiantian Yang , Zhiqian Chen

Pre-trained large language models(LLMs) have attracted increasing attention in biomedical domains due to their success in natural language processing. However, the complex traits and heterogeneity of multi-sources genomics data pose…

Computation and Language · Computer Science 2025-11-25 Yanjun Lyu , Zihao Wu , Lu Zhang , Jing Zhang , Yiwei Li , Wei Ruan , Zhengliang Liu , Zeyu Zhang , Xiang Li , Rongjie Liu , Chao Huang , Wentao Li , Tianming Liu , Dajiang Zhu

Knowledge base construction entails acquiring structured information to create a knowledge base of factual and relational data, facilitating question answering, information retrieval, and semantic understanding. The challenge called…

Computation and Language · Computer Science 2023-10-13 Dong Yang , Xu Wang , Remzi Celebi

Recent advancements in deep learning, particularly large language models (LLMs), made a significant impact on how researchers study microbiome and metagenomics data. Microbial protein and genomic sequences, like natural languages, form a…

Quantitative Methods · Quantitative Biology 2024-09-18 Binghao Yan , Yunbi Nam , Lingyao Li , Rebecca A. Deek , Hongzhe Li , Siyuan Ma

The growing deluge of scientific publications demands text analysis tools that can help scientists and policy-makers navigate, forecast and beneficially guide scientific research. Recent advances in natural language understanding driven by…

Computation and Language · Computer Science 2021-04-14 Brendan Chambers , James Evans

Multimodal knowledge graphs (MKGs), which intuitively organize information in various modalities, can benefit multiple practical downstream tasks, such as recommendation systems, and visual question answering. However, most MKGs are still…

Artificial Intelligence · Computer Science 2023-07-10 Ke Liang , Sihang Zhou , Yue Liu , Lingyuan Meng , Meng Liu , Xinwang Liu

Transcription factors are proteins that regulate the expression of genes by binding to specific genomic regions known as Transcription Factor Binding Sites (TFBSs), typically located in the promoter regions of those genes. Accurate…

Machine Learning · Computer Science 2025-02-04 Nimisha Ghosh , Pratik Dutta , Daniele Santoni

Multivariate time series forecasting poses an ongoing challenge across various disciplines. Time series data often exhibit diverse intra-series and inter-series correlations, contributing to intricate and interwoven dependencies that have…

Machine Learning · Computer Science 2024-01-02 Wanlin Cai , Yuxuan Liang , Xianggen Liu , Jianshuai Feng , Yuankai Wu

Recently, deep learning based facial landmark detection (FLD) methods have achieved considerable success. However, in challenging scenarios such as large pose variations, illumination changes, and facial expression variations, they still…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Jun Wan , Xinyu Xiong , Ning Chen , Zhihui Lai , Jie Zhou , Wenwen Min

Proteins, essential to biological systems, perform functions intricately linked to their three-dimensional structures. Understanding the relationship between protein structures and their amino acid sequences remains a core challenge in…

Quantitative Methods · Quantitative Biology 2024-11-04 Liang He , Peiran Jin , Yaosen Min , Shufang Xie , Lijun Wu , Tao Qin , Xiaozhuan Liang , Kaiyuan Gao , Yuliang Jiang , Tie-Yan Liu

Supervised models trained to predict properties from representations have been achieving high accuracy on a variety of tasks. For instance, the BERT family seems to work exceptionally well on the downstream task from NER tagging to the…

Computation and Language · Computer Science 2020-12-22 Tejas Vaidhya , Ayush Kaushal

Contextual pretrained language models, such as BERT (Devlin et al., 2019), have made significant breakthrough in various NLP tasks by training on large scale of unlabeled text re-sources.Financial sector also accumulates large amount of…

Computation and Language · Computer Science 2020-07-10 Yi Yang , Mark Christopher Siy UY , Allen Huang

This work combines information about the dialogue history encoded by pre-trained model with a meaning representation of the current system utterance to realize contextual language generation in task-oriented dialogues. We utilize the…

Computation and Language · Computer Science 2021-11-30 Ye Liu , Wolfgang Maier , Wolfgang Minker , Stefan Ultes

Using a single model across various tasks is beneficial for training and applying deep neural sequence models. We address the problem of developing generalist representations of text that can be used to perform a range of different tasks…

Computation and Language · Computer Science 2022-12-06 Zhaozhen Xu , Nello Cristianini

Tabular data is prevalent across diverse domains in machine learning. With the rapid progress of deep tabular prediction methods, especially pretrained (foundation) models, there is a growing need to evaluate these methods systematically…

Machine Learning · Computer Science 2025-11-10 Han-Jia Ye , Si-Yang Liu , Hao-Run Cai , Qi-Le Zhou , De-Chuan Zhan

Recent studies have highlighted the limitations of large language models in mathematical reasoning, particularly their inability to capture the underlying logic. Inspired by meta-learning, we propose that models should acquire not only…

Computation and Language · Computer Science 2024-12-19 Kejie Chen , Lin Wang , Qinghai Zhang , Renjun Xu

In industry, the reliability of rotating machinery is critical for production efficiency and safety. Current methods of Prognostics and Health Management (PHM) often rely on task-specific models, which face significant challenges in…

Machine Learning · Computer Science 2025-06-13 Yilin Wang , Yifei Yu , Kong Sun , Peixuan Lei , Yuxuan Zhang , Enrico Zio , Aiguo Xia , Yuanxiang Li