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In this paper, we introduce a new vision-language pre-trained model -- ImageBERT -- for image-text joint embedding. Our model is a Transformer-based model, which takes different modalities as input and models the relationship between them.…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Di Qi , Lin Su , Jia Song , Edward Cui , Taroon Bharti , Arun Sacheti

Pathology text mining is a challenging task given the reporting variability and constant new findings in cancer sub-type definitions. However, successful text mining of a large pathology database can play a critical role to advance 'big…

Computation and Language · Computer Science 2022-05-17 Thiago Santos , Amara Tariq , Susmita Das , Kavyasree Vayalpati , Geoffrey H. Smith , Hari Trivedi , Imon Banerjee

Motivation: Bacteriophages are viruses infecting bacteria. Being key players in microbial communities, they can regulate the composition/function of microbiome by infecting their bacterial hosts and mediating gene transfer. Recently,…

Genomics · Quantitative Biology 2022-08-15 Jiayu Shang , Xubo Tang , Ruocheng Guo , Yanni Sun

Representation learning is a critical ingredient for natural language processing systems. Recent Transformer language models like BERT learn powerful textual representations, but these models are targeted towards token- and sentence-level…

Computation and Language · Computer Science 2020-05-21 Arman Cohan , Sergey Feldman , Iz Beltagy , Doug Downey , Daniel S. Weld

Deep learning (DL) based predictive models from electronic health records (EHR) deliver impressive performance in many clinical tasks. Large training cohorts, however, are often required to achieve high accuracy, hindering the adoption of…

Computation and Language · Computer Science 2020-05-27 Laila Rasmy , Yang Xiang , Ziqian Xie , Cui Tao , Degui Zhi

Large-scale pre-trained models like BERT, have obtained a great success in various Natural Language Processing (NLP) tasks, while it is still a challenge to adapt them to the math-related tasks. Current pre-trained models neglect the…

Computation and Language · Computer Science 2021-05-04 Shuai Peng , Ke Yuan , Liangcai Gao , Zhi Tang

The recent advancement of pre-trained Transformer models has propelled the development of effective text mining models across various biomedical tasks. However, these models are primarily learned on the textual data and often lack the…

Computation and Language · Computer Science 2021-07-02 Sriram Pingali , Shweta Yadav , Pratik Dutta , Sriparna Saha

Predicting gene function from its DNA sequence is a fundamental challenge in biology. Many deep learning models have been proposed to embed DNA sequences and predict their enzymatic function, leveraging information in public databases…

Pretrained Foundation Models (PFMs) are regarded as the foundation for various downstream tasks with different data modalities. A PFM (e.g., BERT, ChatGPT, and GPT-4) is trained on large-scale data which provides a reasonable parameter…

Exploring the functions of genes and gene products is crucial to a wide range of fields, including medical research, evolutionary biology, and environmental science. However, discovering new functions largely relies on expensive and…

Machine Learning · Computer Science 2025-01-06 Yuwei Miao , Yuzhi Guo , Hehuan Ma , Jingquan Yan , Feng Jiang , Rui Liao , Junzhou Huang

Climate change is threatening human health in unprecedented orders and many ways. These threats are expected to grow unless effective and evidence-based policies are developed and acted upon to minimize or eliminate them. Attaining such a…

Computation and Language · Computer Science 2022-12-02 B. Jalalzadeh Fard , S. A. Hasan , J. E. Bell

Metagenomic binning aims to cluster DNA fragments from mixed microbial samples into their respective genomes, a critical step for downstream analyses of microbial communities. Existing methods rely on deterministic representations, such as…

Machine Learning · Computer Science 2025-10-01 Abdulkadir Celikkanat , Andres R. Masegosa , Mads Albertsen , Thomas D. Nielsen

Inferring gene regulatory networks (GRNs) from single-cell RNA sequencing (scRNA-seq) data is a complex challenge that requires capturing the intricate relationships between genes and their regulatory interactions. In this study, we tackle…

Machine Learning · Computer Science 2024-07-26 Sindhura Kommu , Yizhi Wang , Yue Wang , Xuan Wang

Recent advances in natural language processing (NLP) have been driven bypretrained language models like BERT, RoBERTa, T5, and GPT. Thesemodels excel at understanding complex texts, but biomedical literature, withits domain-specific…

Computation and Language · Computer Science 2025-07-28 K. Sahit Reddy , N. Ragavenderan , Vasanth K. , Ganesh N. Naik , Vishalakshi Prabhu , Nagaraja G. S

The extraction of chemical-gene relations plays a pivotal role in understanding the intricate interactions between chemical compounds and genes, with significant implications for drug discovery, disease understanding, and biomedical…

Computation and Language · Computer Science 2026-02-05 Mai H. Nguyen , Shibani Likhite , Jiawei Tang , Darshini Mahendran , Bridget T. McInnes

Metagenomics is a powerful approach to study genetic content of environmental samples that has been strongly promoted by NGS technologies. To cope with massive data involved in modern metagenomic projects, recent tools [4, 39] rely on the…

Genomics · Quantitative Biology 2016-03-17 Karel Brinda , Maciej Sykulski , Gregory Kucherov

Federated Learning (FL) is an emerging paradigm that enables multiple users to collaboratively train a robust model in a privacy-preserving manner without sharing their private data. Most existing approaches of FL only consider traditional…

Computer Vision and Pattern Recognition · Computer Science 2023-12-13 I-Jieh Liu , Ci-Siang Lin , Fu-En Yang , Yu-Chiang Frank Wang

We consider controllable DNA sequence design, where sequences are generated by conditioning on specific biological properties. While language models (LMs) such as GPT and BERT have achieved remarkable success in natural language generation,…

Machine Learning · Computer Science 2025-12-10 Xingyu Su , Xiner Li , Yuchao Lin , Ziqian Xie , Degui Zhi , Shuiwang Ji

To improve the accessibility of smart devices and to simplify their usage, building models which understand user interfaces (UIs) and assist users to complete their tasks is critical. However, unique challenges are proposed by UI-specific…

Computer Vision and Pattern Recognition · Computer Science 2021-08-11 Chongyang Bai , Xiaoxue Zang , Ying Xu , Srinivas Sunkara , Abhinav Rastogi , Jindong Chen , Blaise Aguera y Arcas

Lately, pre-trained language models advanced the field of natural language processing (NLP). The introduction of Bidirectional Encoders for Transformers (BERT) and its optimized version RoBERTa have had significant impact and increased the…

Computation and Language · Computer Science 2025-06-13 Raphael Scheible , Fabian Thomczyk , Patric Tippmann , Victor Jaravine , Martin Boeker