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Recent developments in large language models (LLMs) have unlocked new opportunities for healthcare, from information synthesis to clinical decision support. These new LLMs are not just capable of modeling language, but can also act as…

Human-Computer Interaction · Computer Science 2023-09-21 Nikita Mehandru , Brenda Y. Miao , Eduardo Rodriguez Almaraz , Madhumita Sushil , Atul J. Butte , Ahmed Alaa

This paper introduces an approach that combines the language reasoning capabilities of large language models (LLMs) with the benefits of local training to tackle complex, domain-specific tasks. Specifically, the authors demonstrate their…

Computation and Language · Computer Science 2023-08-04 V. K. Cody Bumgardner , Aaron Mullen , Sam Armstrong , Caylin Hickey , Jeff Talbert

Recently, large language models such as GPT-2 have shown themselves to be extremely adept at text generation and have also been able to achieve high-quality results in many downstream NLP tasks such as text classification, sentiment…

Computation and Language · Computer Science 2019-11-22 Sam Witteveen , Martin Andrews

Large Language Models (LLMs) are revolutionizing bioinformatics, enabling advanced analysis of DNA, RNA, proteins, and single-cell data. This survey provides a systematic review of recent advancements, focusing on genomic sequence modeling,…

Computation and Language · Computer Science 2026-03-03 Zhenyu Wang , Zikang Wang , Jiyue Jiang , Pengan Chen , Xiangyu Shi , Yu Li

ChatGPT is phenomenal. However, it is prohibitively expensive to train and refine such giant models. Fortunately, small language models are flourishing and becoming more and more competent. We call them "mini-giants". We argue that open…

Computation and Language · Computer Science 2024-07-09 Zhengping Zhou , Lezhi Li , Xinxi Chen , Andy Li

Large Language Models (LLMs) have catalyzed significant advancements in Natural Language Processing (NLP), yet they encounter challenges such as hallucination and the need for domain-specific knowledge. To mitigate these, recent…

Computation and Language · Computer Science 2025-07-01 Yucheng Hu , Yuxing Lu

With the increasing application of large language models (LLMs) in the medical domain, evaluating these models' performance using benchmark datasets has become crucial. This paper presents a comprehensive survey of various benchmark…

This paper explores the potential of using Large Language Models (LLMs) to automate the evaluation of responses in medical Question and Answer (Q\&A) systems, a crucial form of Natural Language Processing. Traditionally, human evaluation…

Computation and Language · Computer Science 2024-09-04 Jack Krolik , Herprit Mahal , Feroz Ahmad , Gaurav Trivedi , Bahador Saket

This paper presents CaseGPT, an innovative approach that combines Large Language Models (LLMs) and Retrieval-Augmented Generation (RAG) technology to enhance case-based reasoning in the healthcare and legal sectors. The system addresses the…

Information Retrieval · Computer Science 2024-07-12 Rui Yang

Large multimodal language models (LMMs) have achieved significant success in general domains. However, due to the significant differences between medical images and text and general web content, the performance of LMMs in medical scenarios…

Computer Vision and Pattern Recognition · Computer Science 2023-06-23 Weihao Gao , Zhuo Deng , Zhiyuan Niu , Fuju Rong , Chucheng Chen , Zheng Gong , Wenze Zhang , Daimin Xiao , Fang Li , Zhenjie Cao , Zhaoyi Ma , Wenbin Wei , Lan Ma

Creating written products is essential to modern life, including writings about one's identity and personal experiences. However, writing is often a difficult activity that requires extensive effort to frame the central ideas, the pursued…

Computation and Language · Computer Science 2023-12-29 Alex Doboli

Scientific workflow systems are increasingly popular for expressing and executing complex data analysis pipelines over large datasets, as they offer reproducibility, dependability, and scalability of analyses by automatic parallelization on…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-07-09 Mario Sänger , Ninon De Mecquenem , Katarzyna Ewa Lewińska , Vasilis Bountris , Fabian Lehmann , Ulf Leser , Thomas Kosch

Federal research funding shapes the direction, diversity, and impact of the US scientific enterprise. Large language models (LLMs) are rapidly diffusing into scientific practice, holding substantial promise while raising widespread…

Digital Libraries · Computer Science 2026-04-28 Yifan Qian , Zhe Wen , Alexander C. Furnas , Yue Bai , Erzhuo Shao , Dashun Wang

At the heart of radiological practice is the challenge of integrating complex imaging data with clinical information to produce actionable insights. Nuanced application of language is key for various activities, including managing requests,…

Reporting quality is an important topic in clinical trial research articles, as it can impact clinical decisions. In this article, we test the ability of large language models to assess the reporting quality of this type of article using…

Computation and Language · Computer Science 2025-10-07 Mathieu Laï-king , Patrick Paroubek

There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using…

The integration of Large Language Models (LLMs) into medical applications has sparked widespread interest across the healthcare industry, from drug discovery and development to clinical decision support, assisting telemedicine, medical…

Computation and Language · Computer Science 2024-12-03 Zifeng Wang , Hanyin Wang , Benjamin Danek , Ying Li , Christina Mack , Hoifung Poon , Yajuan Wang , Pranav Rajpurkar , Jimeng Sun

This paper presents the development and application of a Large Language Model Retrieval-Augmented Generation (LLM-RAG) system tailored for nanotechnology research. The system leverages the capabilities of a sophisticated language model to…

Computation and Language · Computer Science 2025-03-03 Achuth Chandrasekhar , Omid Barati Farimani , Olabode T. Ajenifujah , Janghoon Ock , Amir Barati Farimani

Large language models (LLMs) are increasingly impacting human society, particularly in textual information. Based on more than 30,000 papers and 1,000 presentations from machine learning conferences, we examined and compared the words used…

Computation and Language · Computer Science 2024-10-23 Mingmeng Geng , Caixi Chen , Yanru Wu , Dongping Chen , Yao Wan , Pan Zhou

The drug development process necessitates that pharmacologists undertake various tasks, such as reviewing literature, formulating hypotheses, designing experiments, and interpreting results. Each stage requires accessing and querying vast…

Computation and Language · Computer Science 2023-08-01 Hong Lu , Chuan Li , Yinheng Li , Jie Zhao