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Related papers: Pretraining Strategy for Neural Potentials

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Pretraining on Graph Neural Networks (GNNs) has shown great power in facilitating various downstream tasks. As pretraining generally requires huge amount of data and computational resources, the pretrained GNNs are high-value Intellectual…

Machine Learning · Computer Science 2025-06-03 Enyan Dai , Minhua Lin , Suhang Wang

Molecular Graph Neural Networks (GNNs) are increasingly common in drug discovery, particularly for Quantitative Structure-Activity Relationship (QSAR) studies; yet, their superiority compared to classical molecular featurisation approaches…

Machine Learning · Computer Science 2026-05-12 Sam Money-Kyrle , Markus Dablander , Thierry Hanser , Stephane Werner , Charlotte M. Deane , Garrett M. Morris

Recently, graph neural networks (GNNs) have been shown powerful capacity at modeling structural data. However, when adapted to downstream tasks, it usually requires abundant task-specific labeled data, which can be extremely scarce in…

Machine Learning · Computer Science 2022-03-04 Yupeng Hou , Binbin Hu , Wayne Xin Zhao , Zhiqiang Zhang , Jun Zhou , Ji-Rong Wen

Graph Neural Networks (GNNs) are powerful models for graph-structured data, with broad applications. However, the interplay between GNN parameter optimization, expressivity, and generalization remains poorly understood. We address this by…

Machine Learning · Computer Science 2025-09-16 Samir Moustafa , Lorenz Kummer , Simon Fetzel , Nils M. Kriege , Wilfried N. Gansterer

Graph Neural Networks (GNNs) have emerged as a powerful tool to capture intricate network patterns, achieving success across different domains. However, existing GNNs require careful domain-specific architecture designs and training from…

Machine Learning · Computer Science 2025-05-30 Jingzhe Liu , Haitao Mao , Zhikai Chen , Bingheng Li , Wenqi Fan , Mingxuan Ju , Tong Zhao , Neil Shah , Jiliang Tang

Pretrained Graph Neural Networks have been widely adopted for various molecular property prediction tasks. Despite their ability to encode structural and relational features of molecules, traditional fine-tuning of such pretrained GNNs on…

Machine Learning · Computer Science 2024-01-30 Vishal Dey , Xia Ning

Machine learning approaches have become popular for molecular modeling tasks, including molecular force fields and properties prediction. Traditional supervised learning methods suffer from scarcity of labeled data for particular tasks,…

Chemical Physics · Physics 2022-11-29 Xiang Gao , Weihao Gao , Wenzhi Xiao , Zhirui Wang , Chong Wang , Liang Xiang

Graphs can model complex relationships between objects, enabling a myriad of Web applications such as online page/article classification and social recommendation. While graph neural networks(GNNs) have emerged as a powerful tool for graph…

Machine Learning · Computer Science 2023-02-28 Zemin Liu , Xingtong Yu , Yuan Fang , Xinming Zhang

In this work, we propose to train a graph neural network via resampling from a graphon estimate obtained from the underlying network data. More specifically, the graphon or the link probability matrix of the underlying network is first…

Machine Learning · Computer Science 2021-09-07 Ziqing Hu , Yihao Fang , Lizhen Lin

Many important problems involving molecular property prediction from 3D structures have limited data, posing a generalization challenge for neural networks. In this paper, we describe a pre-training technique based on denoising that…

Learning-based precoding has been shown able to be implemented in real-time, jointly optimized with channel acquisition, and robust to imperfect channels. Yet previous works rarely explain the design choices and learning performance, and…

Signal Processing · Electrical Eng. & Systems 2024-02-02 Baichuan Zhao , Jia Guo , Chenyang Yang

Deep learning techniques have gained considerable attention for their ability to accelerate MRI data acquisition while maintaining scan quality. In this work, we present a convolutional neural network (CNN) based framework for learning…

Image and Video Processing · Electrical Eng. & Systems 2025-09-23 Aryan Dhar , Siddhant Gautam , Saiprasad Ravishankar

Pre-training GNNs to extract transferable knowledge and apply it to downstream tasks has become the de facto standard of graph representation learning. Recent works focused on designing self-supervised pre-training tasks to extract useful…

Machine Learning · Computer Science 2024-04-24 Zhe Zhao , Pengkun Wang , Xu Wang , Haibin Wen , Xiaolong Xie , Zhengyang Zhou , Qingfu Zhang , Yang Wang

In recent years, graph pre-training has gained significant attention, focusing on acquiring transferable knowledge from unlabeled graph data to improve downstream performance. Despite these recent endeavors, the problem of negative transfer…

Machine Learning · Computer Science 2023-06-09 Yuxuan Cao , Jiarong Xu , Carl Yang , Jiaan Wang , Yunchao Zhang , Chunping Wang , Lei Chen , Yang Yang

Graph neural networks (GNNs) are a type of neural network capable of learning on graph-structured data. However, training GNNs on large-scale graphs is challenging due to iterative aggregations of high-dimensional features from neighboring…

Machine Learning · Computer Science 2024-09-18 Nikolai Merkel , Pierre Toussing , Ruben Mayer , Hans-Arno Jacobsen

Graph neural networks (GNNs) have extended the success of deep neural networks (DNNs) to non-Euclidean graph data, achieving ground-breaking performance on various tasks such as node classification and graph property prediction.…

Machine Learning · Computer Science 2021-12-17 Tianfeng Liu , Yangrui Chen , Dan Li , Chuan Wu , Yibo Zhu , Jun He , Yanghua Peng , Hongzheng Chen , Hongzhi Chen , Chuanxiong Guo

Graph neural networks (GNNs) integrate deep architectures and topological structure modeling in an effective way. However, the performance of existing GNNs would decrease significantly when they stack many layers, because of the…

Machine Learning · Computer Science 2021-07-07 Kaixiong Zhou , Xiao Huang , Daochen Zha , Rui Chen , Li Li , Soo-Hyun Choi , Xia Hu

Pre-training on graph neural networks (GNNs) aims to learn transferable knowledge for downstream tasks with unlabeled data, and it has recently become an active research area. The success of graph pre-training models is often attributed to…

Machine Learning · Computer Science 2023-11-22 Jiarong Xu , Renhong Huang , Xin Jiang , Yuxuan Cao , Carl Yang , Chunping Wang , Yang Yang

Constructing transferable descriptors for conformation representation of molecular and biological systems finds numerous applications in drug discovery, learning-based molecular dynamics, and protein mechanism analysis. Geometric graph…

Machine Learning · Computer Science 2024-10-30 Zihan Pengmei , Zhengyuan Shen , Zichen Wang , Marcus Collins , Huzefa Rangwala

Recent advances in graph neural networks (GNNs) have enabled more comprehensive modeling of molecules and molecular systems, thereby enhancing the precision of molecular property prediction and molecular simulations. Nonetheless, as the…

Machine Learning · Computer Science 2023-10-31 Filip Ekström Kelvinius , Dimitar Georgiev , Artur Petrov Toshev , Johannes Gasteiger