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Related papers: Hybrid Physics-Based and Data-Driven Modeling of V…

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Three-dimensional (3D) finite-element simulations of cardiovascular flows provide high-fidelity predictions to support cardiovascular medicine, but their high computational cost limits clinical practicality. Reduced-order models (ROMs)…

Computational Engineering, Finance, and Science · Computer Science 2025-09-01 Natalia L. Rubio , Eric F. Darve , Alison L. Marsden

Cardiovascular diseases are a leading cause of death in the world, driving the development of patient-specific and benchmark models for blood flow analysis. This chapter provides a theoretical overview of the main categories of Reduced…

Numerical Analysis · Mathematics 2025-10-21 Pierfrancesco Siena , Pasquale Claudio Africa , Michele Girfoglio , Gianluigi Rozza

This paper presents a physics-based data-driven method to learn predictive reduced-order models (ROMs) from high-fidelity simulations, and illustrates it in the challenging context of a single-injector combustion process. The method…

Computational Physics · Physics 2020-07-14 Renee Swischuk , Boris Kramer , Cheng Huang , Karen Willcox

Reduced-order models based on physics are a popular choice in cardiovascular modeling due to their efficiency, but they may experience reduced accuracy when working with anatomies that contain numerous junctions or pathological conditions.…

This paper deals with the development of a Reduced-Order Model (ROM) to investigate haemodynamics in cardiovascular applications. It employs the use of Proper Orthogonal Decomposition (POD) for the computation of the basis functions and the…

Numerical Analysis · Mathematics 2025-01-24 Pierfrancesco Siena , Pasquale Claudio Africa , Michele Girfoglio , Gianluigi Rozza

Simulating fluid flows in different virtual scenarios is of key importance in engineering applications. However, high-fidelity, full-order models relying, e.g., on the finite element method, are unaffordable whenever fluid flows must be…

Fluid Dynamics · Physics 2021-11-24 Stefania Fresca , Andrea Manzoni

Accurate and efficient modeling of cardiac blood flow is crucial for advancing data-driven tools in cardiovascular research and clinical applications. Recently, the accuracy and availability of computational fluid dynamics (CFD)…

Fluid Dynamics · Physics 2025-07-30 Eneko Lazpita , Jesus Garicano-Mena , Soledad Le Clainche

In this paper, we develop data-driven closure/correction terms to increase the pressure and velocity accuracy of reduced order models (ROMs) for fluid flows. Specifically, we propose the first pressure-based data-driven variational…

Numerical Analysis · Mathematics 2023-01-25 Anna Ivagnes , Giovanni Stabile , Andrea Mola , Traian Iliescu , Gianluigi Rozza

We propose a machine learning-based method to build a system of differential equations that approximates the dynamics of 3D electromechanical models for the human heart, accounting for the dependence on a set of parameters. Specifically,…

Numerical Analysis · Mathematics 2022-04-06 Francesco Regazzoni , Matteo Salvador , Luca Dedè , Alfio Quarteroni

High-fidelity numerical simulations such as Computational Fluid Dynamics (CFD) have been proven effective in analysing haemodynamics, offering insight into many vascular conditions. However, these methods often face challenges of high…

Reduced order modeling (ROM) techniques are numerical methods that approximate the solution of parametric partial differential equation (PDE) by properly combining the high-fidelity solutions of the problem obtained for several…

Numerical Analysis · Mathematics 2023-08-08 M. Girfoglio , L. Scandurra , F. Ballarin , G. Infantino , F. Nicolò , A. Montalto , G. Rozza , R. Scrofani , M. Comisso , F. Musumeci

Hybrid physics-machine learning models are increasingly being used in simulations of transport processes. Many complex multiphysics systems relevant to scientific and engineering applications include multiple spatiotemporal scales and…

Fluid Dynamics · Physics 2021-06-09 Shady E. Ahmed , Omer San , Kursat Kara , Rami Younis , Adil Rasheed

Cardio-mechanical models can be used to support clinical decision-making. Unfortunately, the substantial computational effort involved in many cardiac models hinders their application in the clinic, despite the fact that they may provide…

Computational Engineering, Finance, and Science · Computer Science 2026-05-19 Robin Willems , Peter Förster , Sebastian Schöps , Olaf van der Sluis , Clemens V. Verhoosel

Physics-based 0D reduced-order models provide computationally lightweight predictions of cardiovascular flows, resolving bulk hemodynamics in fractions of a second that would take days to solve using traditional 3D finite-element…

Computational Engineering, Finance, and Science · Computer Science 2026-04-03 Natalia L. Rubio , Eric F. Darve , Alison L. Marsden

The investigation of fluid-solid systems is very important in a lot of industrial processes. From a computational point of view, the simulation of such systems is very expensive, especially when a huge number of parametric configurations…

While data-driven techniques are powerful tools for reduced-order modeling of systems with chaotic dynamics, great potential remains for leveraging known physics (i.e. a full-order model (FOM)) to improve predictive capability. We develop a…

Machine Learning · Computer Science 2025-07-30 Alex Guo , Michael D. Graham

Reduced-order models (ROMs) are widely used in fluid engineering to enable rapid prediction of flow fields for parametric analysis, design optimization, and control applications. Proper orthogonal decomposition (POD) is commonly employed to…

Fluid Dynamics · Physics 2026-02-25 Yuto Nakamura , Shintaro Sato , Naofumi Ohnishi

The complexity of the cardiovascular system needs to be accurately reproduced in order to promptly acknowledge health conditions; to this aim, advanced multifidelity and multiphysics numerical models are crucial. On one side, Full Order…

Predictive modeling of blood flow and pressure have numerous applications ranging from non-invasive assessment of functional significance of disease to planning invasive procedures. While several such predictive modeling techniques have…

Reduced Order Modelling (ROM) has been widely used to create lower order, computationally inexpensive representations of higher-order dynamical systems. Using these representations, ROMs can efficiently model flow fields while using…

Fluid Dynamics · Physics 2021-10-13 Pranshu Pant , Ruchit Doshi , Pranav Bahl , Amir Barati Farimani
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