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Adapting machine learning algorithms to better handle the presence of clusters or batch effects within training datasets is important across a wide variety of biological applications. This article considers the effect of ensembling Random…

Machine Learning · Statistics 2025-04-01 Maya Ramchandran , Rajarshi Mukherjee , Giovanni Parmigiani

Imbalanced regression refers to prediction tasks where the target variable is skewed. This skewness hinders machine learning models, especially neural networks, which concentrate on dense regions and therefore perform poorly on…

Machine Learning · Computer Science 2025-08-11 Shayan Alahyari , Mike Domaratzki

Learning classifiers using skewed or imbalanced datasets can occasionally lead to classification issues; this is a serious issue. In some cases, one class contains the majority of examples while the other, which is frequently the more…

Machine Learning · Computer Science 2022-11-11 Satyendra Singh Rawat , Amit Kumar Mishra

Most machine learning techniques are based upon statistical learning theory, often simplified for the sake of computing speed. This paper is focused on the uncertainty aspect of mathematical modeling in machine learning. Regression analysis…

Machine Learning · Computer Science 2022-06-07 Valentin Arkov

Imbalanced data occurs in a wide range of scenarios. The skewed distribution of the target variable elicits bias in machine learning algorithms. One of the popular methods to combat imbalanced data is to artificially balance the data…

Machine Learning · Computer Science 2021-10-26 Firuz Kamalov , Ashraf Elnagar

The prediction of phenotypic traits using high-density genomic data has many applications such as the selection of plants and animals of commercial interest; and it is expected to play an increasing role in medical diagnostics. Statistical…

Methodology · Statistics 2016-09-29 Marco Scutari , Ian Mackay , David Balding

Machine learning techniques always aim to reduce the generalized prediction error. In order to reduce it, ensemble methods present a good approach combining several models that results in a greater forecasting capacity. The Random Machines…

Machine Learning · Statistics 2020-03-31 Anderson Ara , Mateus Maia , Samuel Macêdo , Francisco Louzada

Many machine learning models have been proposed to classify phenotypes from gene expression data. In addition to their good performance, these models can potentially provide some understanding of phenotypes by extracting explanations for…

Genomics · Quantitative Biology 2024-02-05 Myriam Bontonou , Anaïs Haget , Maria Boulougouri , Benjamin Audit , Pierre Borgnat , Jean-Michel Arbona

This study conducts a benchmarking study, comparing 23 different statistical and machine learning methods in a credit scoring application. In order to do so, the models' performance is evaluated over four different data sets in combination…

Econometrics · Economics 2019-07-31 Anna Stelzer

The human gut microbiota is known to contribute to numerous physiological functions of the body and also implicated in a myriad of pathological conditions. Prolific research work in the past few decades have yielded valuable information…

Quantitative Methods · Quantitative Biology 2023-07-12 Isha Thombre , Pavan Kumar Perepu , Shyam Kumar Sudhakar

This paper studies a Markov network model for unbalanced data, aiming to solve the problems of classification bias and insufficient minority class recognition ability of traditional machine learning models in environments with uneven class…

Machine Learning · Computer Science 2025-02-06 Junliang Du , Shiyu Dou , Bohuan Yang , Jiacheng Hu , Tai An

Model trees provide an appealing way to perform interpretable machine learning for both classification and regression problems. In contrast to ``classic'' decision trees with constant values in their leaves, model trees can use linear…

Machine Learning · Computer Science 2026-03-11 Sabino Francesco Roselli , Eibe Frank

Patient-reported outcomes (PROs) directly collected from cancer patients being treated with radiation therapy play a vital role in assisting clinicians in counseling patients regarding likely toxicities. Precise prediction and evaluation of…

Machine Learning · Computer Science 2024-11-19 Yang Yan , Zhong Chen , Cai Xu , Xinglei Shen , Jay Shiao , John Einck , Ronald C Chen , Hao Gao

The increased availability of medical data has significantly impacted healthcare by enabling the application of machine / deep learning approaches in various instances. However, medical datasets are usually small and scattered across…

Training of deep neural networks heavily depends on the data distribution. In particular, the networks easily suffer from class imbalance. The trained networks would recognize the frequent classes better than the infrequent classes. To…

Computer Vision and Pattern Recognition · Computer Science 2020-03-12 Byungju Kim , Junmo Kim

Suicide prediction is the key for prevention, but real data with sufficient positive samples is rare and causes extreme class imbalance. We utilized machine learning (ML) to build the model and deep learning (DL) techniques, like Generative…

Machine Learning · Computer Science 2025-10-21 Vaishnavi Visweswaraiah , Tanvi Banerjee , William Romine

Data pruning is the problem of identifying a core subset that is most beneficial to training and discarding the remainder. While pruning strategies are well studied for discriminative models like those used in classification, little…

Machine Learning · Computer Science 2025-03-17 Rania Briq , Jiangtao Wang , Stefan Kesselheim

Data imbalance is a fundamental challenge in applying language models to biomedical applications, particularly in ICD code prediction tasks where label and demographic distributions are uneven. While state-of-the-art language models have…

Machine Learning · Computer Science 2025-02-17 Precious Jones , Weisi Liu , I-Chan Huang , Xiaolei Huang

Over the past decade, random forest models have become widely used as a robust method for high-dimensional data regression tasks. In part, the popularity of these models arises from the fact that they require little hyperparameter tuning…

Machine Learning · Computer Science 2020-03-18 Shipra Malhotra , John Karanicolas

Refactoring is the process of changing the internal structure of software to improve its quality without modifying its external behavior. Empirical studies have repeatedly shown that refactoring has a positive impact on the…

Software Engineering · Computer Science 2020-09-14 Maurício Aniche , Erick Maziero , Rafael Durelli , Vinicius Durelli