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In this paper we study nonlocal-to-local asymptotics for a tumor-growth model coupling a viscous Cahn-Hilliard equation describing the tumor proportion with a reaction-diffusion equation for the nutrient phase parameter. First, we prove…

Analysis of PDEs · Mathematics 2023-11-20 Elisa Davoli , Elisabetta Rocca , Luca Scarpa , Lara Trussardi

We prove convergence of a sequence of weak solutions of the nonlocal Cahn-Hilliard equation to the strong solution of the corresponding local Cahn-Hilliard equation. The analysis is done in the case of sufficiently smooth bounded domains…

Analysis of PDEs · Mathematics 2023-12-22 Helmut Abels , Christoph Hurm

In the present work, we develop a comprehensive and rigorous analytical framework for a non-local phase-field model that describes tumour growth dynamics. The model is derived by coupling a non-local Cahn-Hilliard equation with a parabolic…

Analysis of PDEs · Mathematics 2025-03-14 Maurizio Grasselli , Luca Melzi , Andrea Signori

This paper provides a unified mathematical analysis of a family of non-local diffuse interface models for tumor growth describing evolutions driven by long-range interactions. These integro-partial differential equations model cell-to-cell…

Analysis of PDEs · Mathematics 2021-07-07 Luca Scarpa , Andrea Signori

We consider a class of nonlocal viscous Cahn-Hilliard equations with Neumann boundary conditions for the chemical potential. The double-well potential is allowed to be singular (e.g. of logarithmic type), while the singularity of the…

Analysis of PDEs · Mathematics 2021-01-19 Elisa Davoli , Luca Scarpa , Lara Trussardi

We study a non-local variant of a diffuse interface model proposed by Hawkins--Darrud et al. (2012) for tumour growth in the presence of a chemical species acting as nutrient. The system consists of a Cahn--Hilliard equation coupled to a…

Analysis of PDEs · Mathematics 2017-03-13 Sergio Frigeri , Kei Fong Lam , Elisabetta Rocca

Existence and uniqueness of solutions for nonlocal Cahn-Hilliard equations with degenerate potential is shown. The nonlocality is described by means of a symmetric singular kernel not falling within the framework of any previous existence…

Analysis of PDEs · Mathematics 2020-12-11 Elisa Davoli , Helene Ranetbauer , Luca Scarpa , Lara Trussardi

In this paper we prove the convergence of a nonlocal version of the Cahn-Hilliard equation to its local counterpart as the nonlocal convolution kernel is scaled using suitable approximations of a Dirac delta in a periodic boundary…

Analysis of PDEs · Mathematics 2020-01-07 Stefano Melchionna , Helene Ranetbauer , Luca Scarpa , Lara Trussardi

We consider a non-local tumour growth model of phase-field type, describing the evolution of tumour cells through proliferation in presence of a nutrient. The model consists of a coupled system, incorporating a non-local Cahn-Hilliard…

Analysis of PDEs · Mathematics 2024-07-29 Matteo Fornoni

We analyze a phase field model for tumor growth consisting of a Cahn-Hilliard-Brinkman system, ruling the evolution of the tumor mass, coupled with an advection-reaction-diffusion equation for a chemical species acting as a nutrient. The…

Analysis of PDEs · Mathematics 2023-07-26 Pierluigi Colli , Gianni Gilardi , Andrea Signori , Jürgen Sprekels

We study a nonlocal Cahn-Hilliard model for a multicomponent mixture with cross-diffusion effects and degenerate mobility. The nonlocality is described by means of a symmetric singular kernel. We define a notion of weak solution adapted to…

Analysis of PDEs · Mathematics 2026-05-22 Elisa Davoli , Greta Marino , Jan-Frederik Pietschmann

This paper deals with a nonlocal model for a hyperbolic phase field system coupling the standard energy balance equation for temperature with a dynamic for the phase variable: the latter includes an inertial term and a nonlocal…

Analysis of PDEs · Mathematics 2024-02-20 Pierluigi Colli , Shunsuke Kurima , Luca Scarpa

We study the nonlocal-to-local convergence for a nonlocal Cahn-Hilliard equation with anisotropic and singular kernels. In particular, we show convergence of weak solutions of the nonlocal Cahn-Hilliard equation to weak solutions of a…

Analysis of PDEs · Mathematics 2025-12-02 Helmut Abels , Yutaka Terasawa

The link between compressible models of tissue growth and the Hele-Shaw free boundary problem of fluid mechanics has recently attracted a lot of attention. In most of these models, only repulsive forces and advection terms are taken into…

Analysis of PDEs · Mathematics 2023-05-11 Charles Elbar , Benoît Perthame , Andrea Poiatti , Jakub Skrzeczkowski

We introduce here a new diffuse interface thermodynamically consistent non-isothermal model for tumor growth in presence of a nutrient in a domain $\Omega \subset \mathbb{R}^3$. In particular our system describes the growth of a tumor…

Analysis of PDEs · Mathematics 2022-12-19 Erica Ipocoana

We provide a rigorous mathematical framework to establish the limit of a nonlocal model of cell-cell adhesion system to a local model. When the parameter of the nonlocality goes to 0, the system tends to a Cahn-Hilliard system with…

Analysis of PDEs · Mathematics 2023-03-22 José A. Carrillo , Charles Elbar , Jakub Skrzeczkowski

In this paper we study a non-local Cahn-Hilliard equation with singular single-well potential and degenerate mobility. This results as a particular case of a more general model derived for a binary, saturated, closed and incompressible…

Analysis of PDEs · Mathematics 2023-06-29 Abramo Agosti , Elisabetta Rocca , Luca Scarpa

We consider a diffuse interface model for tumor growth consisting of a Cahn--Hilliard equation with source terms coupled to a reaction-diffusion equation, which models a tumor growing in the presence of a nutrient species and surrounded by…

Analysis of PDEs · Mathematics 2017-05-04 Harald Garcke , Kei Fong Lam

A nonlocal Cahn-Hilliard model with a nonsmooth potential of double-well obstacle type that promotes sharp interfaces in the solution is presented. To capture long-range interactions between particles, a nonlocal Ginzburg-Landau energy…

Analysis of PDEs · Mathematics 2021-09-13 Olena Burkovska , Max Gunzburger

We introduce a nonisothermal phase-field system of Caginalp type that describes tumor growth under hyperthermia. The model couples a possibly viscous Cahn-Hilliard equation, governing the evolution of the healthy and tumor phases, with an…

Analysis of PDEs · Mathematics 2025-10-13 Giulia Cavalleri , Pierluigi Colli , Elisabetta Rocca
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