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With the global population aging rapidly, Alzheimer's disease (AD) is particularly prominent in older adults, which has an insidious onset and leads to a gradual, irreversible deterioration in cognitive domains (memory, communication,…

Audio and Speech Processing · Electrical Eng. & Systems 2023-03-15 Jinchao Li , Kaitao Song , Junan Li , Bo Zheng , Dongsheng Li , Xixin Wu , Xunying Liu , Helen Meng

Alzheimer's Disease (AD) early detection is critical for enabling timely intervention and improving patient outcomes. This paper presents a DMV framework using Llama3-70B and GPT-4o as embedding models to analyze clinical notes and predict…

Machine Learning · Computer Science 2025-02-07 Peng Zhang , Divya Chaudhary

Alzheimer's disease (AD), a degenerative brain condition, can benefit from early prediction to slow its progression. As the disease progresses, patients typically undergo brain atrophy. Current prediction methods for Alzheimers disease…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Xin Honga , Jie Lin , Minghui Wang

Deep learning, a cutting-edge machine learning approach, outperforms traditional machine learning in identifying intricate structures in complex high-dimensional data, particularly in the domain of healthcare. This study focuses on…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Nida Nasir , Muneeb Ahmed , Neda Afreen , Mustafa Sameer

Research related to automatically detecting Alzheimer's disease (AD) is important, given the high prevalence of AD and the high cost of traditional methods. Since AD significantly affects the content and acoustics of spontaneous speech,…

Computation and Language · Computer Science 2020-08-05 Aparna Balagopalan , Benjamin Eyre , Frank Rudzicz , Jekaterina Novikova

A Magnetoencephalography (MEG) time-series recording consists of multi-channel signals collected by superconducting sensors, with each signal's intensity reflecting magnetic field changes over time at the sensor location. Automating…

Signal Processing · Electrical Eng. & Systems 2025-01-22 Hanyang Dong , Shurong Sheng , Xiongfei Wang , Jiahong Gao , Yi Sun , Wanli Yang , Kuntao Xiao , Pengfei Teng , Guoming Luan , Zhao Lv

The traditional methods for detecting autism spectrum disorder (ASD) are expensive, subjective, and time-consuming, often taking years for a diagnosis, with many children growing well into adolescence and even adulthood before finally…

Neurons and Cognition · Quantitative Biology 2022-11-15 James Orme-Rogers , Ajitesh Srivastava

Deep learning is significantly advancing the analysis of electroencephalography (EEG) data by effectively discovering highly nonlinear patterns within the signals. Data partitioning and cross-validation are crucial for assessing model…

Signal Processing · Electrical Eng. & Systems 2025-05-20 Federico Del Pup , Andrea Zanola , Louis Fabrice Tshimanga , Alessandra Bertoldo , Livio Finos , Manfredo Atzori

Longitudinal magnetic resonance imaging data is used to model trajectories of change in brain regions of interest to identify areas susceptible to atrophy in those with neurodegenerative conditions like Alzheimer's disease. Most methods for…

Applications · Statistics 2024-07-25 Robert Zielinski , Kun Meng , Ani Eloyan

Autism Spectrum Disorder (ASD) is a developmental disorder that often impairs a child's normal development of the brain. According to CDC, it is estimated that 1 in 6 children in the US suffer from development disorders, and 1 in 68…

Signal Processing · Electrical Eng. & Systems 2019-07-03 Yasith Jayawardana , Mark Jaime , Sashi Thapaliya , Sampath Jayarathna

Biomedical decision making involves multiple signal processing, either from different sensors or from different channels. In both cases, information fusion plays a significant role. A deep learning based electroencephalogram channels'…

Signal Processing · Electrical Eng. & Systems 2025-08-05 Fábio Mendonça , Sheikh Shanawaz Mostafa , Diogo Freitas , Fernando Morgado-Dias , Antonio G. Ravelo-García

The assessment of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) associated with brain changes remains a challenging task. Recent studies have demonstrated that combination of multi-modality imaging techniques can better…

Machine Learning · Computer Science 2022-09-26 Jun Yu , Zhaoming Kong , Liang Zhan , Li Shen , Lifang He

Objective While Alzheimer's disease (AD) and frontotemporal dementia (FTD) show some common memory deficits, these two disorders show partially overlapping complex spatiotemporal patterns of neural dynamics. The objective of this study is…

Neurons and Cognition · Quantitative Biology 2025-07-14 Sungwoo Ahn , Evie A. Malaia , Leonid L Rubchinsky

Structural magnetic resonance imaging (sMRI) is widely used for brain neurological disease diagnosis; while longitudinal MRIs are often collected to monitor and capture disease progression, as clinically used in diagnosing Alzheimer's…

Computer Vision and Pattern Recognition · Computer Science 2023-12-18 Qiuhui Chen , Yi Hong

Reliable Alzheimer's disease (AD) diagnosis increasingly relies on multimodal assessments combining structural Magnetic Resonance Imaging (MRI) and Electronic Health Records (EHR). However, deploying these models is bottlenecked by modality…

Computer Vision and Pattern Recognition · Computer Science 2026-03-04 Guanchen Wu , Zhe Huang , Yuzhang Xie , Runze Yan , Akul Chopra , Deqiang Qiu , Xiao Hu , Fei Wang , Carl Yang

This article addresses the issue of representing electroencephalographic (EEG) signals in an efficient way. While classical approaches use a fixed Gabor dictionary to analyze EEG signals, this article proposes a data-driven method to obtain…

Machine Learning · Computer Science 2013-03-22 Quentin Barthélemy , Cédric Gouy-Pailler , Yoann Isaac , Antoine Souloumiac , Anthony Larue , Jérôme I. Mars

Accurate prediction of clinical scores is critical for early detection and prognosis of Alzheimers disease (AD). While existing approaches primarily focus on forecasting the ADAS-Cog global score, they often overlook the predictive value of…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Nur Amirah Abd Hamid , Mohd Shahrizal Rusli , Muhammad Thaqif Iman Mohd Taufek , Mohd Ibrahim Shapiai , Daphne Teck Ching Lai

Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…

Machine Learning · Computer Science 2025-08-06 Tatwadarshi P Nagarhalli , Sanket Patil , Vishal Pande , Uday Aswalekar , Prafulla Patil

In this work, we delve into the EEG classification task in the domain of visual brain decoding via two frameworks, involving two different learning paradigms. Considering the spatio-temporal nature of EEG data, one of our frameworks is…

Human-Computer Interaction · Computer Science 2024-08-12 Akanksha Sharma , Jyoti Nigam , Abhishek Rathore , Arnav Bhavsar

Using deep learning methods to classify EEG signals can accurately identify people's emotions. However, existing studies have rarely considered the application of the information in another domain's representations to feature selection in…

Signal Processing · Electrical Eng. & Systems 2023-03-22 Kexin Zhu , Xulong Zhang , Jianzong Wang , Ning Cheng , Jing Xiao