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Recent evidence has shown that structural magnetic resonance imaging (MRI) is an effective tool for Alzheimer's disease (AD) prediction and diagnosis. While traditional MRI-based diagnosis uses images acquired at a single time point, a…

Applications · Statistics 2021-11-02 Xiaowu Dai

Sleep staging is critical for assessing sleep quality and diagnosing sleep disorders. However, capturing both the spatial and temporal relationships within electroencephalogram (EEG) signals during different sleep stages remains…

Signal Processing · Electrical Eng. & Systems 2023-08-09 Xinliang Zhou , Chenyu Liu , Jiaping Xiao , Yang Liu

We propose a new representation learning solution for the classification of cognitive load based on Electroencephalogram (EEG). Our method integrates both time and frequency domains by first passing the raw EEG signals through the…

Human-Computer Interaction · Computer Science 2025-11-18 Prithila Angkan , Amin Jalali , Paul Hungler , Ali Etemad

Current studies about motor imagery based rehabilitation training systems for stroke subjects lack an appropriate analytic method, which can achieve a considerable classification accuracy, at the same time detects gradual changes of imagery…

Machine Learning · Statistics 2014-09-19 Hao Zhang , Liqing Zhang

{Introduction: } Dementia is a neurological disorder associated with aging that can cause a loss of cognitive functions, impacting daily life. Alzheimer's disease (AD) is the most common cause of dementia, accounting for 50--70\% of cases,…

Neurons and Cognition · Quantitative Biology 2023-11-07 Zaineb Ajra , Binbin Xu , Gérard Dray , Jacky Montmain , Stéphane Perrey

The electroencephalographic (EEG) signals provide highly informative data on brain activities and functions. However, their heterogeneity and high dimensionality may represent an obstacle for their interpretation. The introduction of a…

Neural and Evolutionary Computing · Computer Science 2023-10-26 Aurora Saibene , Francesca Gasparini

We demonstrate an application of spherical harmonic decomposition to analysis of the human electroencephalogram (EEG). We implement two methods and discuss issues specific to analysis of hemispherical, irregularly sampled data. Performance…

Biological Physics · Physics 2009-11-06 Brett M. Wingeier , Paul L. Nunez , Richard B. Silberstein

Alzheimer's disease is a progressive neurological disorder characterized by cognitive impairment and memory loss. With the increasing aging population, the incidence of AD is continuously rising, making early diagnosis and intervention an…

Image and Video Processing · Electrical Eng. & Systems 2023-11-23 Guian Fang , Mengsha Liu , Yi Zhong , Zhuolin Zhang , Jiehui Huang , Zhenchao Tang , Calvin Yu-Chian Chen

Electroencephalography (EEG) offers detailed access to neural dynamics but remains constrained by noise and trial-by-trial variability, limiting decoding performance in data-restricted or complex paradigms. Data augmentation is often…

Signal Processing · Electrical Eng. & Systems 2025-11-18 Woojae Jeong , Wenhui Cui , Kleanthis Avramidis , Takfarinas Medani , Shrikanth Narayanan , Richard Leahy

Electroencephalogram (EEG) technology, particularly high-density EEG (HD EEG) devices, is widely used in fields such as neuroscience. HD EEG devices improve the spatial resolution of EEG by placing more electrodes on the scalp, which meet…

Signal Processing · Electrical Eng. & Systems 2025-02-25 Shuqiang Wang , Tong Zhou , Yanyan Shen , Ye Li , Guoheng Huang , Yong Hu

Magnetic Resonance Imaging (MRI) provides detailed structural information, while functional MRI (fMRI) captures temporal brain activity. In this work, we present a multimodal deep learning framework that integrates MRI and fMRI for…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Anima Kujur , Zahra Monfared

The uncertainty of clinical examinations frequently leads to irregular observation intervals in longitudinal imaging data, posing challenges for modeling disease progression.Most existing imaging-based disease prediction models operate in…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Xin Hong , Ying Shi , Yinhao Li , Yen-Wei Chen

Alzheimer's disease (AD) is characterized by complex and largely unknown progression dynamics affecting the brain's morphology. Although the disease evolution spans decades, to date we cannot rely on long-term data to model the pathological…

Applications · Statistics 2019-08-14 Clement Abi Nader , Nicholas Ayache , Philippe Robert , Marco Lorenzi

Timely diagnosis is important for saving the life of epileptic patients. In past few years, a lot of treatments are available for epilepsy. These treatments require use of anti-seizure drugs but are not effective in controlling frequency of…

Machine Learning · Computer Science 2021-11-08 Shivam Gupta , Jyoti Meena , O. P Gupta

EEG is a non-invasive technique for recording brain bioelectric activity, which has potential applications in various fields such as human-computer interaction and neuroscience. However, there are many difficulties in analyzing EEG data,…

Signal Processing · Electrical Eng. & Systems 2018-01-18 Yumeng Ye , Haichun Liu , TianHong Zhang , Changchun Pan , Genke Yang , JiJun Wang , Robert C. Qiu

The ability of Deep Learning to process and extract relevant information in complex brain dynamics from raw EEG data has been demonstrated in various recent works. Deep learning models, however, have also been shown to perform best on large…

Machine Learning · Computer Science 2023-10-17 Dung Truong , Muhammad Abdullah Khalid , Arnaud Delorme

Imaging and genomic data offer distinct and rich features, and their integration can unveil new insights into the complex landscape of diseases. In this study, we present a novel approach utilizing radiogenomic data including structural MRI…

Machine Learning · Computer Science 2025-05-16 Aditya Raj , Golrokh Mirzaei

Previous works in the literature apply 3D spatial-only models on 4D functional MRI data leading to possible sub-par feature extraction to be used for downstream tasks like classification. In this work, we aim to develop a novel 4D…

Image and Video Processing · Electrical Eng. & Systems 2025-06-04 Javier Salazar Cavazos , Scott Peltier

Electrophysiological observation plays a major role in epilepsy evaluation. However, human interpretation of brain signals is subjective and prone to misdiagnosis. Automating this process, especially seizure detection relying on scalp-based…

Machine Learning · Computer Science 2018-07-06 David Ahmedt-Aristizabal , Clinton Fookes , Kien Nguyen , Sridha Sridharan

MEG and EEG are noninvasive functional neuroimaging techniques that provide recordings of brain activity with high temporal resolution, and thus provide a unique window to study fast time-scale neural dynamics in humans. However, the…

Applications · Statistics 2015-11-13 Camilo Lamus , Matti S. Hamalainen , Emery N. Brown , Patrick L. Purdon