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Glaucoma, a leading cause of irreversible blindness, necessitates early detection for accurate and timely intervention to prevent irreversible vision loss. In this study, we present a novel deep learning framework that leverages the…
Glaucoma is a chronic eye disease characterized by optic neuropathy, leading to irreversible vision loss. It progresses gradually, often remaining undiagnosed until advanced stages. Early detection is crucial to monitor atrophy and develop…
Glaucoma is one of the leading causes of irreversible blindness worldwide. Glaucoma prognosis is essential for identifying at-risk patients and enabling timely intervention to prevent blindness. Many existing approaches rely on historical…
Glaucoma is a progressive optic neuropathy characterized by structural damage to the optic nerve head and functional changes in the visual field. Detecting glaucoma early is crucial to preventing loss of eyesight. However, medical datasets…
Diagnosing glaucoma progression is critical for limiting irreversible vision loss. A common method for assessing glaucoma progression uses a longitudinal series of visual fields (VF) acquired at regular intervals. VF data are characterized…
Deep learning has enabled breakthroughs in automated diagnosis from medical imaging, with many successful applications in ophthalmology. However, standard medical image classification approaches only assess disease presence at the time of…
Glaucoma disease progression, as measured by visual field (VF) data, is often defined by periods of relative stability followed by an abrupt decrease in visual ability at some point in time. Determining the transition point of the disease…
We model longitudinal macular thickness measurements to monitor the course of glaucoma and prevent vision loss due to disease progression. The macular thickness varies over a 6$\times$6 grid of locations on the retina with additional…
A major cause of irreversible visual impairment is angle-closure glaucoma, which can be screened through imagery from Anterior Segment Optical Coherence Tomography (AS-OCT). Previous computational diagnostic techniques address this…
The utilization of longitudinal datasets for glaucoma progression prediction offers a compelling approach to support early therapeutic interventions. Predominant methodologies in this domain have primarily focused on the direct prediction…
Optical Coherence Tomography (OCT) imaging plays an important role in glaucoma diagnosis in clinical practice. Early detection and timely treatment can prevent glaucoma patients from permanent vision loss. However, only a dearth of…
Alzheimer's disease (AD), a degenerative brain condition, can benefit from early prediction to slow its progression. As the disease progresses, patients typically undergo brain atrophy. Current prediction methods for Alzheimers disease…
Structural magnetic resonance imaging (sMRI) is widely used for brain neurological disease diagnosis; while longitudinal MRIs are often collected to monitor and capture disease progression, as clinically used in diagnosing Alzheimer's…
Alzheimer's disease (AD) is a neurodegenerative disorder with no known cure that affects tens of millions of people worldwide. Early detection of AD is critical for timely intervention to halt or slow the progression of the disease. In this…
Segmentation of Multiple Sclerosis (MS) lesions in longitudinal brain MR scans is performed for monitoring the progression of MS lesions. We hypothesize that the spatio-temporal cues in longitudinal data can aid the segmentation algorithm.…
Glaucoma is an irreversible ocular disease and is the second leading cause of visual disability worldwide. Slow vision loss and the asymptomatic nature of the disease make its diagnosis challenging. Early detection is crucial for preventing…
Generative AI for automated glaucoma diagnostic report generation faces two predominant challenges: content redundancy in narrative outputs and inadequate highlighting of pathologically significant features including optic disc cupping,…
Identifying objective neuroimaging biomarkers to forecast Alzheimer's disease (AD) progression is crucial for timely intervention. However, this task remains challenging due to the complex dysfunctions in the spatio-temporal characteristics…
Glaucoma is a chronic visual disease that may cause permanent irreversible blindness. Measurement of the cup-to-disc ratio (CDR) plays a pivotal role in the detection of glaucoma in its early stage, preventing visual disparities. Therefore,…
Glaucoma is a severe eye disease that is known to deteriorate optic never fibers, causing cup size to increase, which could result in permanent loss of vision. Glaucoma is the second leading cause of blindness after cataract, but glaucoma…