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The integration of single-cell proteomic data is often hindered by the fragmented nature of targeted antibody panels. To address this limitation, we introduce scpFormer, a transformer-based foundation model designed for single-cell…

Quantitative Methods · Quantitative Biology 2026-04-23 Qifeng Zhou , Lei Yu , Yuzhi Guo , Yuwei Miao , Hehuan Ma , Wenliang Zhong , Lin Xu , Junzhou Huang

State-of-the-art supervised NLP models achieve high accuracy but are also susceptible to failures on inputs from low-data regimes, such as domains that are not represented in training data. As an approximation to collecting ground-truth…

Computation and Language · Computer Science 2023-06-29 Parikshit Bansal , Amit Sharma

Work done to uncover the knowledge encoded within pre-trained language models rely on annotated corpora or human-in-the-loop methods. However, these approaches are limited in terms of scalability and the scope of interpretation. We propose…

Computation and Language · Computer Science 2023-10-23 Basel Mousi , Nadir Durrani , Fahim Dalvi

Prevalent solution for BioNER involves using representation learning techniques coupled with sequence labeling. However, such methods are inherently task-specific, demonstrate poor generalizability, and often require dedicated model for…

Computation and Language · Computer Science 2024-04-30 Junyi Biana , Weiqi Zhai , Xiaodi Huang , Jiaxuan Zheng , Shanfeng Zhu

Large-scale Transformer models have significantly promoted the recent development of natural language processing applications. However, little effort has been made to unify the effective models. In this paper, driven by providing a new set…

Computation and Language · Computer Science 2022-04-12 Dezhou Shen

Even though large language models (LLMs) have demonstrated remarkable capability in solving various natural language tasks, the capability of an LLM to follow human instructions is still a concern. Recent works have shown great improvements…

Computation and Language · Computer Science 2024-03-05 Xinbo Wu , Lav R. Varshney

The Transformer architecture has become prominent in developing large causal language models. However, mechanisms to explain its capabilities are not well understood. Focused on the training process, here we establish a meta-learning view…

Machine Learning · Computer Science 2024-03-26 Xinbo Wu , Lav R. Varshney

Large protein language models are adept at capturing the underlying evolutionary information in primary structures, offering significant practical value for protein engineering. Compared to natural language models, protein amino acid…

Computation and Language · Computer Science 2023-10-27 Yang Tan , Mingchen Li , Pan Tan , Ziyi Zhou , Huiqun Yu , Guisheng Fan , Liang Hong

Large pretrained language models have been performing increasingly well in a variety of downstream tasks via prompting. However, it remains unclear from where the model learns the task-specific knowledge, especially in a zero-shot setup. In…

Computation and Language · Computer Science 2022-05-26 Xiaochuang Han , Yulia Tsvetkov

Choosing a Large Language Model (LLM) for a given task requires comparing many strong candidates, yet standard evaluation relies on costly annotations over fixed evaluation sets. To address this challenge, we develop SELECT-LLM, the first…

Computation and Language · Computer Science 2026-05-26 Yavuz Durmazkeser , Patrik Okanovic , Andreas Kirsch , Torsten Hoefler , Nezihe Merve Gürel

Sign Language (SL) automatic processing slowly progresses bottom-up. The field has seen proposition to handle the video signal, to recognize and synthesize sublexical and lexical units. It starts to see the development of supra-lexical…

Computation and Language · Computer Science 2014-03-19 Rémi Dubot , Christophe Collet

Large language models (LLMs) can capture rich representations of concepts that are useful for real-world tasks. However, language alone is limited. While existing LLMs excel at text-based inferences, health applications require that models…

Computation and Language · Computer Science 2023-05-26 Xin Liu , Daniel McDuff , Geza Kovacs , Isaac Galatzer-Levy , Jacob Sunshine , Jiening Zhan , Ming-Zher Poh , Shun Liao , Paolo Di Achille , Shwetak Patel

Despite recent advancements in speech emotion recognition (SER) models, state-of-the-art deep learning (DL) approaches face the challenge of the limited availability of annotated data. Large language models (LLMs) have revolutionised our…

Sound · Computer Science 2024-06-21 Siddique Latif , Muhammad Usama , Mohammad Ibrahim Malik , Björn W. Schuller

Large language models (LLMs) process and predict sequences containing text to answer questions, and address tasks including document summarization, providing recommendations, writing software and solving quantitative problems. We provide a…

Numerical Analysis · Mathematics 2026-02-02 Ricardo Baptista , Andrew Stuart , Son Tran

In this paper, we study whether transformer-based language models can extract predicate argument structure from simple sentences. We firstly show that language models sometimes confuse which predicates apply to which objects. To mitigate…

Computation and Language · Computer Science 2024-10-07 Akshay Chaturvedi , Nicholas Asher

The aim of this paper is to evaluate whether large language models trained on multi-choice question data can be used to discriminate between medical subjects. This is an important and challenging task for automatic question answering. To…

Computation and Language · Computer Science 2024-03-22 Víctor Ponce-López

Neural language models (LMs) are typically trained using only lexical features, such as surface forms of words. In this paper, we argue this deprives the LM of crucial syntactic signals that can be detected at high confidence using existing…

Computation and Language · Computer Science 2018-03-13 Duncan Blythe , Alan Akbik , Roland Vollgraf

Recent works on form understanding mostly employ multimodal transformers or large-scale pre-trained language models. These models need ample data for pre-training. In contrast, humans can usually identify key-value pairings from a form only…

Computation and Language · Computer Science 2023-05-09 Bhanu Prakash Voutharoja , Lizhen Qu , Fatemeh Shiri

Information extraction tasks require both accurate, efficient, and generalisable models. Classical supervised deep learning approaches can achieve the required performance, but they need large datasets and are limited in their ability to…

Machine Learning · Computer Science 2024-08-02 Ihor Stepanov , Mykhailo Shtopko

Foundation models for single-cell RNA sequencing (scRNA-seq) have shown promising capabilities in capturing gene expression patterns. However, current approaches face critical limitations: they ignore biological prior knowledge encoded in…

Machine Learning · Computer Science 2025-03-04 Mufan Qiu , Xinyu Hu , Fengwei Zhan , Sukwon Yun , Jie Peng , Ruichen Zhang , Bhavya Kailkhura , Jiekun Yang , Tianlong Chen
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