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Medical artificial intelligence (AI) systems frequently lack systematic domain expertise integration, potentially compromising diagnostic reliability. This study presents an ontology-based framework for bone disease diagnosis, developed in…

Artificial Intelligence · Computer Science 2025-06-06 Loan Dao , Ngoc Quoc Ly

Multimodal machine learning integrating histopathology and molecular data shows promise for cancer prognostication. We systematically reviewed studies combining whole slide images (WSIs) and high-throughput omics to predict overall…

Quantitative Methods · Quantitative Biology 2025-07-30 Charlotte Jennings , Andrew Broad , Lucy Godson , Emily Clarke , David Westhead , Darren Treanor

Multidisciplinary tumour boards (MDTBs) play a central role in oncology decision-making but require manual processes and structuring large volumes of heterogeneous clinical information, resulting in a substantial documentation burden. In…

Computation and Language · Computer Science 2026-01-28 Luis Lorenzo , Marcos Montana-Mendez , Sergio Figueiras , Miguel Boubeta , Cristobal Bernardo-Castineira

Artificial intelligence (AI)-based methods are showing promise in multiple medical-imaging applications. Thus, there is substantial interest in clinical translation of these methods, requiring in turn, that they be evaluated rigorously. In…

High-throughput omics profiling advancements have greatly enhanced cancer patient stratification. However, incomplete data in multi-omics integration presents a significant challenge, as traditional methods like sample exclusion or…

Genomics · Quantitative Biology 2024-01-17 Shihao Ma , Andy G. X. Zeng , Benjamin Haibe-Kains , Anna Goldenberg , John E Dick , Bo Wang

The new era of artificial intelligence demands large-scale ultrafast hardware for machine learning. Optical artificial neural networks process classical and quantum information at the speed of light, and are compatible with silicon…

Medical Physics · Physics 2018-12-24 D. Pierangeli , V. Palmieri , G. Marcucci , C. Moriconi , G. Perini , M. De Spirito , M. Papi , C. Conti

Radiotherapy planning is a critical aspect of cancer treatment, where the optimal selection of beam directions and dose distributions significantly impacts treatment efficacy and patient outcomes. Traditionally, this process involves…

Medical Physics · Physics 2023-12-05 Keshav Kumar K. , NVSL Narasimham , A. Ramakrishna Prasad

In the field of lung cancer research, particularly in the analysis of overall survival (OS), artificial intelligence (AI) serves crucial roles with specific aims. Given the prevalent issue of missing data in the medical domain, our primary…

Machine Learning · Computer Science 2026-03-13 Camillo Maria Caruso , Valerio Guarrasi , Sara Ramella , Paolo Soda

We present a machine learning method capable of accurately detecting chromosome abnormalities that cause blood cancers directly from microscope images of the metaphase stage of cell division. The pipeline is built on a series of fine-tuned…

Breast cancer is one of the leading causes of death among women across the globe. It is difficult to treat if detected at advanced stages, however, early detection can significantly increase chances of survival and improves lives of…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Unaiza Sajid , Rizwan Ahmed Khan , Shahid Munir Shah , Sheeraz Arif

Motivation: Tumor classification using Imaging Mass Spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are…

Machine Learning · Statistics 2018-06-28 Jens Behrmann , Christian Etmann , Tobias Boskamp , Rita Casadonte , Jörg Kriegsmann , Peter Maass

Machine learning models have shown exceptional prowess in solving complex issues across various domains. However, these models can sometimes exhibit biased decision-making, resulting in unequal treatment of different groups. Despite…

Machine Learning · Computer Science 2025-06-26 Shuyi Chen , Shixiang Zhu

Artificial intelligence (AI)-driven decision support systems can improve diagnostic accuracy and efficiency in computational pathology. However, collaboration between human experts and AI may introduce cognitive biases such as automation…

Human-Computer Interaction · Computer Science 2026-03-16 Emely Rosbach , Jonas Ammeling , Jonathan Ganz , Christof Albert Bertram , Thomas Conrad , Andreas Riener , Marc Aubreville

Cancer prognosis is a critical task that involves predicting patient outcomes and survival rates. To enhance prediction accuracy, previous studies have integrated diverse data modalities, such as clinical notes, medical images, and genomic…

Machine Learning · Computer Science 2025-02-04 Jie Peng , Shuang Zhou , Longwei Yang , Yiran Song , Mohan Zhang , Kaixiong Zhou , Feng Xie , Mingquan Lin , Rui Zhang , Tianlong Chen

Cancer cachexia is a multifactorial syndrome characterized by progressive muscle wasting, metabolic dysfunction, and systemic inflammation, leading to reduced quality of life and increased mortality. Despite extensive research, no single…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Sabeen Ahmed , Nathan Parker , Margaret Park , Evan W. Davis , Jennifer B. Permuth , Matthew B. Schabath , Yasin Yilmaz , Ghulam Rasool

Gene selection plays a pivotal role in oncology research for improving outcome prediction accuracy and facilitating cost-effective genomic profiling for cancer patients. This paper introduces two gene selection strategies for deep…

Genomics · Quantitative Biology 2024-03-05 Akhila Krishna , Ravi Kant Gupta , Pranav Jeevan , Amit Sethi

The widespread application of Artificial Intelligence (AI) techniques has significantly influenced the development of new therapeutic agents. These computational methods can be used to design and predict the properties of generated…

Neural and Evolutionary Computing · Computer Science 2024-08-21 Arthur Cerveira , Frederico Kremer , Darling de Andrade Lourenço , Ulisses B Corrêa

Chemotherapeutic response of cancer cells to a given compound is one of the most fundamental information one requires to design anti-cancer drugs. Recent advances in producing large drug screens against cancer cell lines provided an…

Genomics · Quantitative Biology 2018-07-17 Mehmet Tan , Ozan Fırat Özgül , Batuhan Bardak , Işıksu Ekşioğlu , Suna Sabuncuoğlu

The rapid development of diagnostic technologies in healthcare is leading to higher requirements for physicians to handle and integrate the heterogeneous, yet complementary data that are produced during routine practice. For instance, the…

Machine Learning · Computer Science 2023-01-30 Can Cui , Haichun Yang , Yaohong Wang , Shilin Zhao , Zuhayr Asad , Lori A. Coburn , Keith T. Wilson , Bennett A. Landman , Yuankai Huo

Machine-based brain tumor segmentation can help doctors make better diagnoses. However, the complex structure of brain tumors and expensive pixel-level annotations present challenges for automatic tumor segmentation. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2024-08-05 Ruitao Xie , Limai Jiang , Xiaoxi He , Yi Pan , Yunpeng Cai
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