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Inhibitory neurons play a crucial role in maintaining persistent neuronal activity. Although connected extensively through electrical synapses (gap-junctions), these neurons also exhibit interactions through chemical synapses in certain…

Neurons and Cognition · Quantitative Biology 2021-04-08 R. Janaki , A. S. Vytheeswaran

A central idea in understanding brains and building artificial intelligence is that structure determines function. Yet, how the brain's complex structure arises from a limited set of genetic instructions remains a key question. The ultra…

Neurons and Cognition · Quantitative Biology 2026-01-28 Xingyu Liu , Yubin Li , Guozhang Chen

Functional brain network has been widely studied to understand the relationship between brain organization and behavior. In this paper, we aim to explore the functional connectivity of brain network under a \emph{multi-step} cognitive task…

Neurons and Cognition · Quantitative Biology 2017-12-06 Shi-Min Cai , Wei Chen , Dong-Bai Liu , Ming Tang , Xun Chen

Recent advances in experimental techniques enable the simultaneous recording of activity from thousands of neurons in the brain, presenting both an opportunity and a challenge: to build meaningful, scalable models of large neural…

Biological Physics · Physics 2025-08-05 Luca Di Carlo , Francesca Mignacco , Christopher W. Lynn , William Bialek

One major challenge of neuroscience is finding interesting structures in a seemingly disorganized neural activity. Often these structures have computational implications that help to understand the functional role of a particular brain…

Neurons and Cognition · Quantitative Biology 2023-09-01 Srdjan Ostojic , Stefano Fusi

The mammalian brain could contain dense and sparse network connectivity structures, including both excitatory and inhibitory neurons, but is without any clearly defined output layer. The neurons have time constants, which mean that the…

Neurons and Cognition · Quantitative Biology 2021-06-04 Udaya B. Rongala , Henrik Jörntell

The brain is an assembly of neuronal populations interconnected by structural pathways. Brain activity is expressed on and constrained by this substrate. Therefore, statistical dependencies between functional signals in directly connected…

Neurons and Cognition · Quantitative Biology 2019-09-11 Maria Giulia Preti , Dimitri Van De Ville

Today the human brain can be modeled as a graph where nodes represent different regions and links stand for statistical interactions between their activities as recorded by different neuroimaging techniques. Empirical studies have lead to…

Neurons and Cognition · Quantitative Biology 2017-11-01 J. H. Martínez , J. M. Buldú , D. Papo , F. De Vico Fallani , M. Chavez

Despite the fact that the phenomenon of bursting activity is important for functioning of living neural networks, the mechanisms of its origin are still not clear. In this paper, we propose a new phenomenological model that can explain the…

Neurons and Cognition · Quantitative Biology 2023-03-01 Nikita Barabash , Tatiana Levanova , Sergey Stasenko

Empirical estimates of the dimensionality of neural population activity are often much lower than the population size. Similar phenomena are also observed in trained and designed neural network models. These experimental and computational…

Neurons and Cognition · Quantitative Biology 2020-02-11 Omri Barak , Sandro Romani

We construct and analyze a rate-based neural network model in which self-interacting units represent clusters of neurons with strong local connectivity and random inter-unit connections reflect long-range interactions. When sufficiently…

Disordered Systems and Neural Networks · Physics 2015-06-22 Merav Stern , Haim Sompolinsky , L. F. Abbott

We explore how to study dynamical interactions between brain regions using functional multilayer networks whose layers represent the different frequency bands at which a brain operates. Specifically, we investigate the consequences of…

Neurons and Cognition · Quantitative Biology 2017-09-15 Javier M. Buldú , Mason A. Porter

In the brain, coherent neuronal activities often appear simultaneously in multiple frequency bands, e.g., as combinations of alpha (8-12 Hz), beta (12.5-30 Hz), gamma (30-120 Hz) oscillations, among others. These rhythms are believed to…

Neurons and Cognition · Quantitative Biology 2023-04-26 Tianyi Wu , Yuhang Cai , Ruilin Zhang , Zhongyi Wang , Louis Tao , Zhuo-Cheng Xiao

We study the characteristics of weak signal detection by a recurrent neuronal network with plastic synaptic coupling. It is shown that in the presence of an asynchronous component in synaptic transmission, the network acquires selectivity…

Neurons and Cognition · Quantitative Biology 2015-05-13 Vladislav Volman , Herbert Levine

The brain is a complex organ characterized by heterogeneous patterns of structural connections supporting unparalleled feats of cognition and a wide range of behaviors. New noninvasive imaging techniques now allow these patterns to be…

Neurons and Cognition · Quantitative Biology 2020-04-03 Christopher W. Lynn , Danielle S. Bassett

The brain is a highly complex organ consisting of a myriad of subsystems that flexibly interact and adapt over time and context to enable perception, cognition, and behavior. Understanding the multi-scale nature of the brain, i.e., how…

Neurons and Cognition · Quantitative Biology 2025-01-17 Adam S. Charles

The integration and transmission of information in the brain are dependent on the interplay between structural and dynamical properties. Implicit in any pursuit aimed at understanding neural dynamics from appropriate sets of mathematically…

Neurons and Cognition · Quantitative Biology 2020-06-30 Joshua M. Roldan , Sebastian Pardo G. , Vivek Kurien George , Gabriel A. Silva

Intrinsic brain activity is characterized by highly structured co-activations between different regions, whose origin is still under debate. In this paper, we address the question whether it is possible to unveil how the underlying…

Encoding models are used for predicting brain activity in response to sensory stimuli with the objective of elucidating how sensory information is represented in the brain. Encoding models typically comprise a nonlinear transformation of…

Neurons and Cognition · Quantitative Biology 2017-03-13 Umut Güçlü , Marcel A. J. van Gerven

Recent developments in experimental neuroscience make it possible to simultaneously record the activity of thousands of neurons. However, the development of analysis approaches for such large-scale neural recordings have been slower than…

Neurons and Cognition · Quantitative Biology 2022-10-18 Rufus Mitchell-Heggs , Seigfred Prado , Giuseppe P. Gava , Mary Ann Go , Simon R. Schultz