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Multimorbidity, the co-occurrence of two or more chronic diseases such as diabetes, obesity or cardiovascular diseases in one patient, is a frequent phenomenon. To make care more efficient, it is of relevance to understand how different…

Medical Physics · Physics 2019-08-05 Nils Haug , Stefan Thurner , Alexandra Kautzky-Willer , Michael Gyimesi , Peter Klimek

Sustained high levels of blood glucose in type 2 diabetes (T2DM) can have disastrous long-term health consequences. An essential component of clinical interventions for T2DM is monitoring dietary intake to keep plasma glucose levels within…

Quantitative Methods · Quantitative Biology 2022-06-24 Zepeng Huo , Bobak J. Mortazavi , Theodora Chaspari , Nicolaas Deutz , Laura Ruebush , Ricardo Gutierrez-Osuna

Machine Learning and Artificial Intelligence can be widely used to diagnose chronic diseases so that necessary precautionary treatment can be done in critical time. Diabetes Mellitus which is one of the major diseases can be easily…

Machine Learning · Computer Science 2021-11-22 V. Vakil , S. Pachchigar , C. Chavda , S. Soni

With continuous glucose monitoring (CGM), data-driven models on blood glucose prediction have been shown to be effective in related work. However, such (CGM) systems are not always available, e.g., for a patient at home. In this work, we…

Computers and Society · Computer Science 2024-04-10 Tu Nguyen , Markus Rokicki

Patients with Type I Diabetes (T1D) must take insulin injections to prevent the serious long term effects of hyperglycemia - high blood glucose (BG). Patients must also be careful not to inject too much insulin because this could induce…

Machine Learning · Computer Science 2019-04-01 Neil C. Borle , Edmond A. Ryan , Russell Greiner

Diabetes Mellitus is a metabolic disorder which may result in severe and potentially fatal complications if not well-treated and monitored. In this study, a quantitative analysis of the data collected using CGM (Continuous Glucose…

Quantitative Methods · Quantitative Biology 2023-08-15 Giulia Elena Aliffi , Giovanni Nastasi , Vittorio Romano , Dario Pitocco , Alessandro Rizzi , Elvin J. Moore , Andrea De Gaetano

Medical events of interest, such as mortality, often happen at a low rate in electronic medical records, as most admitted patients survive. Training models with this imbalance rate (class density discrepancy) may lead to suboptimal…

Machine Learning · Computer Science 2022-08-02 Zepeng Huo , Xiaoning Qian , Shuai Huang , Zhangyang Wang , Bobak J. Mortazavi

Heart disease remains a leading cause of mortality and morbidity worldwide, necessitating the development of accurate and reliable predictive models to facilitate early detection and intervention. While state of the art work has focused on…

Machine Learning · Computer Science 2025-05-23 Mahade Hasan , Farhana Yasmin , Xue Yu

Diabetes, especially T2DM, continues to be a significant health problem. One of the major concerns associated with diabetes is the development of its complications. Diabetic nephropathy, one of the chronic complication of diabetes,…

Cardiovascular diseases state as one of the greatest risks of death for the general population. Late detection in heart diseases highly conditions the chances of survival for patients. Age, sex, cholesterol level, sugar level, heart rate,…

Artificial Intelligence and Machine Learning (AI/ML) models used in clinical settings are increasingly deployed to support clinical decision-making. However, when training data become stale due to changes in demographics, environment, or…

Artificial Intelligence · Computer Science 2026-04-28 Ioannis Bilionis , Ricardo C. Berrios , Luis Fernandez-Luque , Carlos Castillo

Multiple types or views of data (e.g. genetics, proteomics) measured on the same set of individuals are now popularly generated in many biomedical studies. A particular interest might be the detection of sample subgroups (e.g. subtypes of…

Methodology · Statistics 2025-05-09 Kaifeng Yang , Thierry Chekouo , Sandra E. Safo

Predictive uncertainty-a model's self awareness regarding its accuracy on an input-is key for both building robust models via training interventions and for test-time applications such as selective classification. We propose a novel…

Machine Learning · Computer Science 2024-01-04 Nishant Jain , Karthikeyan Shanmugam , Pradeep Shenoy

Type 2 diabetes (T2DM), one of the most prevalent chronic diseases, affects the glucose metabolism of the human body, which decreases the quantity of life and brings a heavy burden on social medical care. Patients with T2DM are more likely…

Quantitative Methods · Quantitative Biology 2020-07-01 Wei Wang , Gangqiang Hu , Bo Yuan , Shandong Ye , Chao Chen , YaYun Cui , Xi Zhang , Liting Qian

Preprint Note: This is the author preprint version of a paper accepted for presentation at the IISE Annual Conference & Expo 2025. The final version will appear in the official proceedings. Diabetic retinopathy (DR) is a leading cause of…

Machine Learning · Computer Science 2025-10-02 Mahyar Mahmoudi , Tieming Liu

Heart disease is a leading cause of premature death worldwide, particularly among middle-aged and older adults, with men experiencing a higher prevalence. According to the World Health Organization (WHO), non-communicable diseases,…

The aim of this study is to analyze the effect of serum metabolites on diabetic nephropathy (DN) and predict the prevalence of DN through a machine learning approach. The dataset consists of 548 patients from April 2018 to April 2019 in…

Machine Learning · Computer Science 2023-10-25 Jing-Mei Yin , Yang Li , Jun-Tang Xue , Guo-Wei Zong , Zhong-Ze Fang , Lang Zou

Quantitative characterization of disease progression using longitudinal data can provide long-term predictions for the pathological stages of individuals. This work studies the robust modeling of Alzheimer's disease progression using…

Multivariate functional data that are cross-sectionally compositional data are attracting increasing interest in the statistical modeling literature, a major example being trajectories over time of compositions derived from cause-specific…

Methodology · Statistics 2023-11-21 Emanuele Giovanni Depaoli , Marco Stefanucci , Stefano Mazzuco

I present an application of established machine learning techniques to NHANES health survey data for predicting diabetes status. I compare baseline models (logistic regression, random forest, XGBoost) with a hybrid approach that uses an…

Machine Learning · Computer Science 2025-12-03 Mithra D K