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The introduction of Large Language Models (LLMs), and the vast volume of publicly available medical data, amplified the application of NLP to the medical domain. However, LLMs are pretrained on data that are not explicitly relevant to the…

Computation and Language · Computer Science 2023-12-12 Chris Solomou

Large Language Models (LLMs) are increasingly adopted across domains such as education, healthcare, and finance. In healthcare, LLMs support tasks including disease diagnosis, abnormality classification, and clinical decision-making. Among…

Cryptography and Security · Computer Science 2026-03-31 Payel Bhattacharjee , Fengwei Tian , Geoffrey D. Rubin , Joseph Y. Lo , Nirav Merchant , Heidi Hanson , John Gounley , Ravi Tandon

Large Language Models (LLMs) have demonstrated impressive capabilities in role-playing scenarios, particularly in simulating domain-specific experts using tailored prompts. This ability enables LLMs to adopt the persona of individuals with…

Artificial Intelligence · Computer Science 2025-01-14 Xinyao Ma , Rui Zhu , Zihao Wang , Jingwei Xiong , Qingyu Chen , Haixu Tang , L. Jean Camp , Lucila Ohno-Machado

In this paper, we present our approach to extracting structured information from unstructured Electronic Health Records (EHR) [2] which can be used to, for example, study adverse drug reactions in patients due to chemicals in their…

Computation and Language · Computer Science 2020-01-30 Amogh Kamat Tarcar , Aashis Tiwari , Vineet Naique Dhaimodker , Penjo Rebelo , Rahul Desai , Dattaraj Rao

We systematically investigate lightweight strategies to adapt large language models (LLMs) for the task of radiology report summarization (RRS). Specifically, we focus on domain adaptation via pretraining (on natural language, biomedical…

Large language models (LLMs) are increasingly applied in biomedical domains, yet their reliability in drug-safety prediction remains underexplored. In this work, we investigate whether LLMs incorporate socio-demographic information into…

Computation and Language · Computer Science 2025-10-17 Siying Liu , Shisheng Zhang , Indu Bala

Pre-trained language models (PLMs) have achieved remarkable success on various natural language understanding tasks. Simple fine-tuning of PLMs, on the other hand, might be suboptimal for domain-specific tasks because they cannot possibly…

Computation and Language · Computer Science 2022-08-05 Minki Kang , Jinheon Baek , Sung Ju Hwang

While Large Language Models (LLMs) have achieved strong performance on general-purpose language tasks, their deployment in regulated and data-sensitive domains, including insurance, remains limited. Leveraging millions of historical…

Computation and Language · Computer Science 2026-02-20 Zhengda Mo , Zhiyu Quan , Eli O'Donohue , Kaiwen Zhong

Pre-trained Large Language Models (LLMs) often struggle on out-of-domain datasets like healthcare focused text. We explore specialized pre-training to adapt smaller LLMs to different healthcare datasets. Three methods are assessed:…

Computation and Language · Computer Science 2024-04-01 Niall Taylor , Dan Schofield , Andrey Kormilitzin , Dan W Joyce , Alejo Nevado-Holgado

In recent years, pre-trained language models (PLMs) achieve the best performance on a wide range of natural language processing (NLP) tasks. While the first models were trained on general domain data, specialized ones have emerged to more…

Computation and Language · Computer Science 2023-05-08 Yanis Labrak , Adrien Bazoge , Richard Dufour , Mickael Rouvier , Emmanuel Morin , Béatrice Daille , Pierre-Antoine Gourraud

Large Language Models (LLMs) have the potential to accelerate small molecule drug design due to their ability to reason about information from diverse sources and formats. However, their practical utility remains unclear due to the lack of…

Protein language models (PLMs) are becoming practical tools for de novo protein design, yet their dual-use potential raises safety concerns. We show that domain adaptation to specific taxonomic groups can elicit toxic protein generation,…

Machine Learning · Computer Science 2026-03-05 Manuel Fernández Burda , Santiago Aranguri , Iván Arcuschin Moreno , Enzo Ferrante

Large Language Models (LLMs), like LLaMA, have exhibited remarkable performance across various tasks. Nevertheless, when deployed to specific domains such as law or medicine, the models still confront the challenge of a deficiency in…

Computation and Language · Computer Science 2023-10-17 Quzhe Huang , Mingxu Tao , Chen Zhang , Zhenwei An , Cong Jiang , Zhibin Chen , Zirui Wu , Yansong Feng

Recent developments in deep learning have led to a significant innovation in various classic and practical subjects, including speech recognition, computer vision, question answering, information retrieval and so on. In the context of…

Computation and Language · Computer Science 2019-11-01 Li-Phen Yen , Zhen-Yu Wu , Kuan-Yu Chen

In recent years, Large Language Models (LLMs) have emerged as a prominent area of interest across various research domains, including Process Mining (PM). Current applications in PM have predominantly centered on prompt engineering…

Computation and Language · Computer Science 2025-09-04 Rafael Seidi Oyamada , Jari Peeperkorn , Jochen De Weerdt , Johannes De Smedt

Recent advances in natural language processing (NLP) can be largely attributed to the advent of pre-trained language models such as BERT and RoBERTa. While these models demonstrate remarkable performance on general datasets, they can…

We propose a novel approach to enhancing the performance and efficiency of large language models (LLMs) by combining domain prompt routing with domain-specialized models. We introduce a system that utilizes a BERT-based router to direct…

Computation and Language · Computer Science 2024-10-11 Toby Simonds , Kemal Kurniawan , Jey Han Lau

The success of pretrained language models (PLMs) across a spate of use-cases has led to significant investment from the NLP community towards building domain-specific foundational models. On the other hand, in mission critical settings such…

Computation and Language · Computer Science 2024-07-18 Aman Sinha , Timothee Mickus , Marianne Clausel , Mathieu Constant , Xavier Coubez

The utilization of Electronic Health Records (EHRs) for clinical risk prediction is on the rise. However, strict privacy regulations limit access to comprehensive health records, making it challenging to apply standard machine learning…

Computation and Language · Computer Science 2023-12-08 Angeela Acharya , Sulabh Shrestha , Anyi Chen , Joseph Conte , Sanja Avramovic , Siddhartha Sikdar , Antonios Anastasopoulos , Sanmay Das