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Related papers: Mathematical Opportunities in Digital Twins (MATH-…

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Digital Twins are one of the hottest digital trends. In this contribution we will shortly review the concept of Digital Twins and the chances for novel industrial applications. Mathematics are a key enabler and the impact will be…

Computers and Society · Computer Science 2020-01-28 Dirk Hartmann , Herman van der Auweraer

Digital Twin (DT) is a promising technology for the new immersive digital life with a variety of applications in areas such as Industry 4.0, aviation, and healthcare. Proliferation of this technology requires higher data rates, reliability,…

Networking and Internet Architecture · Computer Science 2021-08-13 Hamed Ahmadi , Avishek Nag , Zaheer Khan , Kamran Sayrafian , Susanto Rahadrja

Digital twins are emerging in many industries, typically consisting of simulation models and data associated with a specific physical system. One of the main reasons for developing a digital twin, is to enable the simulation of possible…

Machine Learning · Statistics 2021-03-15 Christian Agrell , Kristina Rognlien Dahl , Andreas Hafver

Digital Twins (DTs) are rapidly emerging as a fundamental brick of engineering cyber-physical systems, but their notion is still mostly bound to specific business domains (e.g. manufacturing), goals (e.g. product design), or application…

Multiagent Systems · Computer Science 2022-11-15 Stefano Mariani , Marco Picone , Alessandro Ricci

Digital twin (DT) technologies have emerged as a solution for real-time data-driven modeling of cyber physical systems (CPS) using the vast amount of data available by Internet of Things (IoT) networks. In this position paper, we elucidate…

Networking and Internet Architecture · Computer Science 2022-04-12 Jithin Jagannath , Keyvan Ramezanpour , Anu Jagannath

A human body digital twin (DT) is a virtual representation of an individual's physiological state, created using real-time data from sensors and medical test devices, with the purpose of simulating, predicting, and optimizing health…

Artificial Intelligence · Computer Science 2024-04-24 Chenyu Tang , Wentian Yi , Edoardo Occhipinti , Yanning Dai , Shuo Gao , Luigi G. Occhipinti

Digital Twins (DTs) represent digital counterparts of physical systems, assets, or processes, referred to as the actual twin (AT). DTs integrate heterogeneous data, models, and semantic technologies to support monitoring, simulation,…

Software Engineering · Computer Science 2026-05-21 Faima Abbasi , Jean-Sébastien Sottet , Cedric Pruski

Recent technological advances have expanded the availability of high-throughput biological datasets, enabling the reliable design of digital twins of biomedical systems or patients. Such computational tools represent key reaction networks…

Quantitative Methods · Quantitative Biology 2025-09-03 Clémence Métayer , Annabelle Ballesta , Julien Martinelli

In this paper, we introduce a decentralized digital twin (DDT) framework for dynamical systems and discuss the prospects of the DDT modeling paradigm in computational science and engineering applications. The DDT approach is built on a…

Machine Learning · Computer Science 2022-07-26 Omer San , Suraj Pawar , Adil Rasheed

Digital Twins (DT) are essentially dynamic data-driven models that serve as real-time symbiotic "virtual replicas" of real-world systems. DT can leverage fundamentals of Dynamic Data-Driven Applications Systems (DDDAS) bidirectional…

Artificial Intelligence · Computer Science 2024-02-01 Nan Zhang , Rami Bahsoon , Nikos Tziritas , Georgios Theodoropoulos

Digital twins (DTs) are increasingly utilized to monitor, manage, and optimize complex systems across various domains, including civil engineering. A core requirement for an effective DT is to act as a fast, accurate, and maintainable…

Software Engineering · Computer Science 2025-08-26 Eduardo de Conto , Blaise Genest , Arvind Easwaran , Nicholas Ng , Shweta Menon

Clinical trials are indispensable for medical research and the development of new treatments. However, clinical trials often involve thousands of participants and can span several years to complete, with a high probability of failure during…

Machine Learning · Computer Science 2024-07-02 Yue Wang , Tianfan Fu , Yinlong Xu , Zihan Ma , Hongxia Xu , Yingzhou Lu , Bang Du , Honghao Gao , Jian Wu

Recent digital advances have popularized predictive maintenance (PMx), offering enhanced efficiency, automation, accuracy, cost savings, and independence in maintenance processes. Yet, PMx continues to face numerous limitations such as poor…

Artificial Intelligence · Computer Science 2024-09-11 Sizhe Ma , Katherine A. Flanigan , Mario Bergés

Human Digital Twins (HDTs) are digital replicas of humans that either mirror a complete human body, some parts of it as can be organs, flows, cells, or even human behaviors. An HDT is a human specific replica application inferred from the…

Other Computer Science · Computer Science 2023-02-08 Heribert Pascual , Xavi Masip Bruin , Albert Alonso , Judit Cerdà

Digital twins (DTs) are redefining healthcare by paving the way for more personalized, proactive, and intelligent medical interventions. As the shift toward personalized care intensifies, there is a growing need for an individual's virtual…

Human-Computer Interaction · Computer Science 2025-03-18 Melvin Mokhtari

Digital Twin (DT) technology revolutionizes industrial processes by enabling the representation of physical entities and their dynamics to enhance productivity and operational efficiency. It has emerged as a vital enabling technology in the…

Networking and Internet Architecture · Computer Science 2026-02-02 Eduardo Freitas , Assis T. de Oliveira Filho , Pedro R. X. do Carmo , Djamel Sadok , Judith Kelner

Optimizing modern wireless networks is exceptionally challenging due to their high dynamism and complexity. While the agentic artificial intelligence (AI) powered by reinforcement learning (RL) offers a promising solution, its practical…

Systems and Control · Electrical Eng. & Systems 2025-11-26 Zhenyu Tao , Wei Xu , Xiaohu You

This work shows how adaptivity can enhance value realization of digital twins in civil engineering. We focus on adapting the state transition models within digital twins represented through probabilistic graphical models. The bi-directional…

Machine Learning · Computer Science 2026-05-12 Eugenio Varetti , Matteo Torzoni , Marco Tezzele , Andrea Manzoni

The growing complexity of healthcare systems requires advanced computational models for real-time monitoring, secure data exchange, and intelligent decision-making. Digital Twins (DTs) provide virtual representations of physical healthcare…

Emerging Technologies · Computer Science 2026-02-18 Asma Taheri Monfared , Andrea Bombarda , Angelo Gargantini , Majid Haghparast

In the manufacturing industry, the digital twin (DT) is becoming a central topic. It has the potential to enhance the efficiency of manufacturing machines and reduce the frequency of errors. In order to fulfill its purpose, a DT must be an…

Systems and Control · Electrical Eng. & Systems 2024-08-26 Zhibo Zhou , Michael Walther , Alexander Verl