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We present a novel Pharmacokinetic/Pharmacodynamic (PK/PD) model for the induction phase of anesthesia, incorporating the $\psi$-Caputo fractional derivative. By employing the Picard iterative process, we derive a solution for a…

Optimization and Control · Mathematics 2023-11-17 Mohamed Abdelaziz Zaitri , Hanaa Zitane , Delfim F. M. Torres

A fractional derivative is a temporally nonlocal operation which is computationally intensive due to inclusion of the accumulated contribution of function values at past times. In order to lessen the computational load while maintaining the…

Numerical Analysis · Mathematics 2021-11-01 Daegeun Yoon , Donghyun You

This work presents an analytical and computational study of fractional-order delay differential equations formulated using both the conformable and Caputo derivatives. For the conformable case, we develop the associated integral,…

We begin with a treatment of the Caputo time-fractional diffusion equation, by using the Laplace transform, to obtain a Volterra intego-differential equation where we may examine the weakly singular nature of this convolution…

Numerical Analysis · Mathematics 2020-01-27 Wesley Davis , Richard Noren , Ke Shi

Mathematical models that accurately predict the mechanical behavior of blood can contribute to the development of biomedical devices and medications which are relevant in clinical applications. The models existing in the literature are…

Fluid Dynamics · Physics 2018-08-27 Corina S. Drapaca , Zhifeng Zhang , Ruifan Meng

We consider a partial differential equation associated with a mathematical model describing the concentration of nutrients in blood which interferes directly on the erythrocyte sedimentation rate in the case of an average fluid velocity…

Tissues and Organs · Quantitative Biology 2017-01-27 José Vanterler da Costa Sousa , Edmundo Capelas de Oliveira , Luiz Alberto Magna

We have used the homotopy analysis method to obtain solutions of linear and nonlinear fractional partial differential differential equations with initial conditions. We replace the first order time derivative by $\psi$-Caputo fractional…

Analysis of PDEs · Mathematics 2020-04-07 D. S. Oliveira , E. Capelas de Oliveira

We show that any given function can be approximated with arbitrary precision by solutions of linear, time-fractional equations of any prescribed order. This extends a recent result by Claudia Bucur, which was obtained for time-fractional…

Analysis of PDEs · Mathematics 2018-11-02 Alessandro Carbotti , Serena Dipierro , Enrico Valdinoci

Fractional differential equations model processes with memory effects, providing a realistic perspective on complex systems. We examine time-delayed differential equations, discussing first-order and fractional Caputo time-delayed…

General Relativity and Quantum Cosmology · Physics 2025-05-08 Bayron Micolta-Riascos , Byron Droguett , Gisel Mattar Marriaga , Genly Leon , Andronikos Paliathanasis , Luis del Campo , Yoelsy Leyva

Recent studies have demonstrated the advantages of fractional-order calculus tools for probing the viscoelastic properties of collagenous tissue, characterizing the arterial blood flow and red cell membrane mechanics, and modeling the…

Systems and Control · Electrical Eng. & Systems 2020-10-21 Mohamed A. Bahloul , Taous-Meriem Laleg Kirati

We present a new numerical tool to solve partial differential equations involving Caputo derivatives of fractional variable order. Three Caputo-type fractional operators are considered, and for each one of them an approximation formula is…

Classical Analysis and ODEs · Mathematics 2015-12-08 Dina Tavares , Ricardo Almeida , Delfim F. M. Torres

In the present paper, we address a class of the fractional derivatives of constant and variable orders for the first time. Fractional-order relaxation equations of constants and variable orders in the sense of Caputo type are modeled from…

Classical Physics · Physics 2017-07-18 Xiao-Jun Yang

In this article we propose a new fractional derivative without singular kernel. We consider the potential application for modeling the steady heat-conduction problem. The analytical solution of the fractional-order heat flow is also…

General Mathematics · Mathematics 2017-07-18 Xiao-Jun Yang , H. M. Srivastava , J. A. Tenreiro Machado

The conformable derivative has been promoted in numerous publications as a new fractional derivative operator. This article provides a critical reassessment of this claim. We demonstrate that the conformable derivative is not a fractional…

Analysis of PDEs · Mathematics 2025-12-30 Aziz El Ghazouani , Fouad Ibrahim Abdou Amir , Khoulane Mohamed , M'hamed Elomari

In this paper, we establish Iyengar type inequalities utilizing $\psi$-Caputo fractional derivatives that is, fractional derivative of a function with respect to another function, which is generalization of some known fractional derivatives…

General Mathematics · Mathematics 2020-10-09 Bhagwat R. Yewale , Deepak B. Pachpatte

We describe and implement a numerical method for modelling the frequency-dependent power-law absorption of ultrasound in tissue, as governed by the first order linear wave equations with a loss taking the form of a fractional time…

Medical Physics · Physics 2025-06-06 Matthew. J. King , Timon. S. Gutleb , B. E. Treeby , B. T. Cox

In the present work, we propose a new parameterization for the concentration flux using fractional derivatives. The fractional order differential equation in the longitudinal and vertical directions is used to obtain the concentration…

Atmospheric and Oceanic Physics · Physics 2018-12-26 A. G. Goulart , M. J. Lazo , J. M. S. Suarez

The momentous objective of this work is to discuss some qualitative properties of solutions such as the estimate on the solutions, the continuous dependence of the solutions on initial conditions as well as the existence and uniqueness of…

Functional Analysis · Mathematics 2021-09-01 Choukri Derbazi , Qasem M. Al-Mdallal , Fahd Jarad , Zidane Baitiche

We describe a general operational method that can be used in the analysis of fractional initial and boundary value problems with additional analytic conditions. As an example, we derive analytic solutions of some fractional generalisation…

Analysis of PDEs · Mathematics 2013-04-04 Roberto Garra , Federico Polito

In this work, we investigate a fractional-order tumor growth model aimed at capturing memory effects and nonlocal temporal dynamics inherent to tumor evolution. The model is formulated using Caputo fractional derivatives and incorporates…

Medical Physics · Physics 2026-03-17 Karen Escutia , Carlos Islas , Pablo Padilla
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