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Artificial Intelligence (AI) can now automate the algorithm selection, feature engineering, and hyperparameter tuning steps in a machine learning workflow. Commonly known as AutoML or AutoAI, these technologies aim to relieve data…

Machine Learning · Computer Science 2020-01-20 Daniel Karl I. Weidele , Justin D. Weisz , Eno Oduor , Michael Muller , Josh Andres , Alexander Gray , Dakuo Wang

We introduce Dialz, a framework for advancing research on steering vectors for open-source LLMs, implemented in Python. Steering vectors allow users to modify activations at inference time to amplify or weaken a 'concept', e.g. honesty or…

Machine Learning · Computer Science 2025-06-04 Zara Siddique , Liam D. Turner , Luis Espinosa-Anke

Virtual staining has emerged as a powerful alternative to traditional histopathological staining techniques, enabling rapid, reagent-free image transformations. However, existing evaluation methods predominantly rely on full-reference image…

Image and Video Processing · Electrical Eng. & Systems 2025-07-18 Qiankai Wang , James E. D. Tweel , Parsin Haji Reza , Anita Layton

In contemporary pathology, multiplexed immunofluorescence (mIF) and multiplex immunohistochemistry (mIHC) present both significant opportunities and challenges. These methodologies shed light on intricate tumor microenvironment…

The process of visually presenting networks is an effective way to understand entity relationships within the networks since it reveals the overall structure and topology of the network. Real networks are extremely difficult to visualize…

Social and Information Networks · Computer Science 2022-09-08 Jayamohan Pillai C. S. , Ayan Chatterjee , Geetha M. , Amitava Mukherjee

Whole slide imaging (WSI) has become the primary modality for digital pathology data. However, due to the size and high-resolution nature of these images, they are generally only accessed in smaller sections or tiles via specialized…

Quantitative Methods · Quantitative Biology 2022-07-07 Praphulla MS Bhawsar , Erich Bremer , Máire A Duggan , Stephen Chanock , Montserrat Garcia-Closas , Joel Saltz , Jonas S Almeida

The promise of multimodal models for real-world applications has inspired research in visualizing and understanding their internal mechanics with the end goal of empowering stakeholders to visualize model behavior, perform model debugging,…

The condvis package is for interactive visualization of sections in data space, showing fitted models on the section, and observed data near the section. The primary goal is the interpretation of complex models, and showing how the observed…

Other Statistics · Statistics 2016-10-04 Mark O'Connell , Catherine B. Hurley , Katarina Domijan

The use of artificial intelligence to enable precision medicine and decision support systems through the analysis of pathology images has the potential to revolutionize the diagnosis and treatment of cancer. Such applications will depend on…

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

Despite the promises of data-driven artificial intelligence (AI), little is known about how we can bridge the gulf between traditional physician-driven diagnosis and a plausible future of medicine automated by AI. Specifically, how can we…

Human-Computer Interaction · Computer Science 2021-02-12 Hongyan Gu , Jingbin Huang , Lauren Hung , Xiang 'Anthony' Chen

Digital pathology has emerged as a transformative approach to tissue analysis, offering unprecedented opportunities for objective, quantitative assessment of histopathological features. However, the complexity of implementing artificial…

Quantitative Methods · Quantitative Biology 2025-09-17 Noor Shaker , Mohamed AbouZleikha , Nuha Shaker

[Purpose] The pathology is decisive for disease diagnosis, but relies heavily on the experienced pathologists. Recently, pathological artificial intelligence (PAI) is thought to improve diagnostic accuracy and efficiency. However, the high…

Image and Video Processing · Electrical Eng. & Systems 2022-05-25 Yuanqing Yang , Kai Sun , Yanhua Gao , Kuangsong Wang , Gang Yu

Histology slide digitization is becoming essential for telepathology (remote consultation), knowledge sharing (education), and using the state-of-the-art artificial intelligence algorithms (augmented/automated end-to-end clinical…

Image and Video Processing · Electrical Eng. & Systems 2024-05-15 Talat Zehra , Joseph Marino , Wendy Wang , Grigoriy Frantsuzov , Saad Nadeem

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Ajit J. Nirmal , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Randomized controlled trials (RCT) are the gold standards for evaluating the efficacy and safety of therapeutic interventions in human subjects. In addition to the pre-specified endpoints, trial participants' experience reveals the time…

Human-Computer Interaction · Computer Science 2024-01-31 Zuotian Li , Xiang Liu , Zelei Cheng , Yingjie Chen , Wanzhu Tu , Jing Su

In this paper, we report the development of a model and a proof-of-concept visual text analytics (VTA) tool to enhance documentdiscovery in a problem-driven visualization research (PDVR) con-text. The proposed model captures the cognitive…

Human-Computer Interaction · Computer Science 2020-09-22 Alejandro Benito-Santos , Roberto Therón

Computational pathology holds substantial promise for improving diagnosis and guiding treatment decisions. Recent pathology foundation models enable the extraction of rich patch-level representations from large-scale whole-slide images…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Xiangde Luo , Jinxi Xiang , Yuanfeng Ji , Ruijiang Li

Automated visualization recommendation facilitates the rapid creation of effective visualizations, which is especially beneficial for users with limited time and limited knowledge of data visualization. There is an increasing trend in…

Human-Computer Interaction · Computer Science 2023-10-19 Songheng Zhang , Haotian Li , Huamin Qu , Yong Wang

For doctors to truly trust artificial intelligence, it can't be a black box. They need to understand its reasoning, almost as if they were consulting a colleague. We created HistoLens1 to be that transparent, collaborative partner. It…

Artificial Intelligence · Computer Science 2025-10-29 Sandeep Vissapragada , Vikrant Sahu , Gagan Raj Gupta , Vandita Singh