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Digital pathology has become a standard in the pathology workflow due to its many benefits. These include the level of detail of the whole slide images generated and the potential immediate sharing of cases between hospitals. Recent…

Human-Computer Interaction · Computer Science 2023-07-18 Cristian Camilo Pulgarín-Ospina , Rocío del Amor , Adrián Colomera , Julio Silva-Rodríguez , Valery Naranjo

Pathologists diagnose cancer using gigapixel whole-slide images (WSIs), but the current digital workflow is fragmented. These multiscale datasets often exceed 100,000 x 100,000 pixels, yet standard 2D monitors restrict the field of view.…

Human-Computer Interaction · Computer Science 2026-02-27 Jai Prakash Veerla , Partha Sai Guttikonda , Helen H. Shang , Mohammad Sadegh Nasr , Cesar Torres , Jacob M. Luber

Digital pathology plays a crucial role in the development of artificial intelligence in the medical field. The digital pathology platform can make the pathological resources digital and networked, and realize the permanent storage of visual…

Human-Computer Interaction · Computer Science 2021-11-11 Jialun Wu , Anyu Mao , Xinrui Bao , Haichuan Zhang , Zeyu Gao , Chunbao Wang , Tieliang Gong , Chen Li

The integration of artificial intelligence (AI) into pathology is advancing precision medicine by improving diagnosis, treatment planning, and patient outcomes. Digitised whole-slide images (WSIs) capture rich spatial and morphological…

We present a visualization tool to exhaustively search and browse through a set of large-scale machine learning datasets. Built on the top of the VizWiz dataset, our dataset browser tool has the potential to support and enable a variety of…

Machine Learning · Computer Science 2019-12-20 Nilavra Bhattacharya , Danna Gurari

Histopathology images; microscopy images of stained tissue biopsies contain fundamental prognostic information that forms the foundation of pathological analysis and diagnostic medicine. However, diagnostics from histopathology images…

Computer Vision and Pattern Recognition · Computer Science 2019-10-30 Aïcha BenTaieb , Ghassan Hamarneh

In pre-clinical pathology, there is a paradox between the abundance of raw data (whole slide images from many organs of many individual animals) and the lack of pixel-level slide annotations done by pathologists. Due to time constraints and…

Computer Vision and Pattern Recognition · Computer Science 2023-02-06 Marco Bertolini , Van-Khoa Le , Jake Pencharz , Andreas Poehlmann , Djork-Arné Clevert , Santiago Villalba , Floriane Montanari

Conventional histopathology has long been essential for disease diagnosis, relying on visual inspection of tissue sections. Immunohistochemistry aids in detecting specific biomarkers but is limited by its single-marker approach, restricting…

Transition from conventional to digital pathology requires a new category of biomedical informatic infrastructure which could facilitate delicate pathological routine. Pathological diagnoses are sensitive to many external factors and is…

Quantitative Methods · Quantitative Biology 2020-01-16 Pargorn Puttapirat , Haichuan Zhang , Jingyi Deng , Yuxin Dong , Jiangbo Shi , Hongyu He , Zeyu Gao , Chunbao Wang , Xiangrong Zhang , Chen Li

Backgr: Digital pathology images are increasingly used both for diagnosis and research, because slide scanners are nowadays broadly available and because the quantitative study of these images yields new insights in systems biology.…

Quantitative Methods · Quantitative Biology 2017-09-08 Christophe Deroulers , David Ameisen , Mathilde Badoual , Chloé Gerin , Alexandre Granier , Marc Lartaud

Advances in digitizing tissue slides and the fast-paced progress in artificial intelligence, including deep learning, have boosted the field of computational pathology. This field holds tremendous potential to automate clinical diagnosis,…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Andrew H. Song , Guillaume Jaume , Drew F. K. Williamson , Ming Y. Lu , Anurag Vaidya , Tiffany R. Miller , Faisal Mahmood

The microscopic examination of surgical tissue remains a cornerstone of disease classification but relies on subjective interpretations and access to highly specialized experts, which can compromise accuracy and clinical care. While…

ivadomed is an open-source Python package for designing, end-to-end training, and evaluating deep learning models applied to medical imaging data. The package includes APIs, command-line tools, documentation, and tutorials. ivadomed also…

Image and Video Processing · Electrical Eng. & Systems 2020-10-26 Charley Gros , Andreanne Lemay , Olivier Vincent , Lucas Rouhier , Anthime Bucquet , Joseph Paul Cohen , Julien Cohen-Adad

Advances in entity-graph based analysis of histopathology images have brought in a new paradigm to describe tissue composition, and learn the tissue structure-to-function relationship. Entity-graphs offer flexible and scalable…

Image and Video Processing · Electrical Eng. & Systems 2021-07-22 Guillaume Jaume , Pushpak Pati , Valentin Anklin , Antonio Foncubierta , Maria Gabrani

Causal inference is a statistical paradigm for quantifying causal effects using observational data. It is a complex process, requiring multiple steps, iterations, and collaborations with domain experts. Analysts often rely on visualizations…

Human-Computer Interaction · Computer Science 2023-03-02 Grace Guo , Ehud Karavani , Alex Endert , Bum Chul Kwon

Biomedical data harmonization is essential for enabling exploratory analyses and meta-studies, but the process of schema matching - identifying semantic correspondences between elements of disparate datasets (schemas) - remains a…

Human-Computer Interaction · Computer Science 2026-04-14 Eden Wu , Dishita G Turakhia , Guande Wu , Christos Koutras , Sarah Keegan , Wenke Liu , Beata Szeitz , David Fenyo , Cláudio T. Silva , Juliana Freire

As the size of images and data products derived from astronomical data continues to increase, new tools are needed to visualize and interact with that data in a meaningful way. Motivated by our own astronomical images taken with the Dark…

Instrumentation and Methods for Astrophysics · Physics 2015-11-19 Fred Moolekamp , Eric Mamajek

The field of digital pathology has seen a proliferation of deep learning models in recent years. Despite substantial progress, it remains rare for other researchers and pathologists to be able to access models published in the literature…

Tissues and Organs · Quantitative Biology 2024-01-15 Jakub R. Kaczmarzyk , Alan O'Callaghan , Fiona Inglis , Tahsin Kurc , Rajarsi Gupta , Erich Bremer , Peter Bankhead , Joel H. Saltz

Deep learning methods have emerged as powerful tools for analyzing histopathological images, but current methods are often specialized for specific domains and software environments, and few open-source options exist for deploying models in…

Phylogenetic analysis, which allow to understand the evolution of bacterial and viral epidemics, requires large quantities of data to be analysed and processed for knowledge extraction. One of the major challenges consists on the…

Populations and Evolution · Quantitative Biology 2024-05-28 Nyckollas Brandão , André Jesus , André Páscoa , Alexandre P. Francisco , Mário Ramirez , Cátia Vaz
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