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Osteolytic metastases located in the vertebrae reduce strength and enhance the risk of vertebral fractures. This risk can be predicted by means of validated finite element models, but their reproducibility needs to be assessed. For that…

Tissues and Organs · Quantitative Biology 2025-03-24 W. Lokbani , V. Allard , T. Broussolle , CY. Barrey , C. B. Confavreux , K. Bruyere , JP. Roux , F. Bermond , H. Follet , D. Mitton

Metastases increase the risk of fracture when affecting the femur. Consequently, clinicians need to know if the patients femur can withstand the stress of daily activities. The current tools used in clinics are not sufficiently precise. A…

Vertebral fractures prediction in clinics lacks of accuracy. The most used scores have limitations in distinguishing between subjects at risk or not. Finite element (FE) models generated from computed tomography (CT) of these patients may…

Computational Engineering, Finance, and Science · Computer Science 2024-02-16 Chiara Garavelli , Alessandra Aldieri , Marco Palanca , Luca Patruno , Marco Viceconti

The precise and accurate segmentation of the vertebral column is essential in the diagnosis and treatment of various orthopedic, neurological, and oncological traumas and pathologies. Segmentation is especially challenging in the presence…

Computer Vision and Pattern Recognition · Computer Science 2016-01-14 Yinong Wang , Jianhua Yao , Holger R. Roth , Joseph E. Burns , Ronald M. Summers

Vertebrae localization, segmentation and identification in CT images is key to numerous clinical applications. While deep learning strategies have brought to this field significant improvements over recent years, transitional and…

Image and Video Processing · Electrical Eng. & Systems 2022-06-27 Di Meng , Edmond Boyer , Sergi Pujades

The outcome of vertebroplasty is hard to predict due to its dependence on complex factors like bone cement and marrow rheologies. Cement leakage could occur if the procedure is done incorrectly, potentially causing adverse complications. A…

Clinical use of finite element analysis requires validation and reproducibility studies. The current study compared two models of vertebral bodies including endplates, on the same experimental dataset and evaluated the influence of the…

Numerical Analysis · Mathematics 2024-02-15 V. Allard , C. Heidsieck , F. Bermond , C. Confavreux , C. Travert , L. Gajny , 3 , W. Skalli , D. Mitton , H. Follet

Symptomatic spinal vertebral compression fractures (VCFs) often require osteoplasty treatment. A cement-like material is injected into the bone to stabilize the fracture, restore the vertebral body height and alleviate pain. Leakage is a…

Osteoporosis induced fractures occur worldwide about every 3 seconds. Vertebral compression fractures are early signs of the disease and considered risk predictors for secondary osteoporotic fractures. We present a detection method to…

Image and Video Processing · Electrical Eng. & Systems 2019-11-06 Joeri Nicolaes , Steven Raeymaeckers , David Robben , Guido Wilms , Dirk Vandermeulen , Cesar Libanati , Marc Debois

We test and simulate the mesoscopic cracking behavior of specimens made of a standard concrete mixture. To this end, we combine stable wedge-splitting fracture experiments performed during X-ray tomography, their analysis with digital…

Mesoscale and Nanoscale Physics · Physics 2025-02-04 Akanksha Mishra , Pietro Carrara , Michele Griffa , Laura De Lorenzis

The aim of this paper is to develop a multiscale hierarchical hybrid model based on finite element analysis and neural network computation to link mesoscopic scale (trabecular network level) and macroscopic (whole bone level) to simulate…

Medical Physics · Physics 2011-07-20 Ridha Hambli , Abdelwahed Barkaoui

Internal properties of a sample can be observed by medical imaging tools, such as ultrasound devices, magnetic resonance imaging (MRI) and optical coherence tomography (OCT) which are based on relying on changes in material density or…

Computer Vision and Pattern Recognition · Computer Science 2020-12-22 Mehrdad Shafiei Dizaji , Devin Harris

Recently, a widely applicable system of hyperbolic partial differential equations has been derived that enables the deterministic computation of a full heterogeneous stress field from a measured deformation field, for example, from a strain…

Materials Science · Physics 2022-09-29 Benjamin C. Cameron , C. Cem Tasan

Simulation of fracturing processes in porous rocks can be divided into two main branches: (i) modeling the rock as a continuum which is enhanced with special features to account for fractures, or (ii) modeling the rock by a discrete (or…

Numerical Analysis · Mathematics 2017-02-07 Halvor Møll Nilsen , Idar Larsen , Xavier Raynaud

X-ray computed tomography (XCT) has become a reliable metrology tool for measuring internal flaws and other microstructural features in engineering materials. However, tracking of material points to measure three-dimensional (3D)…

Materials Science · Physics 2023-04-13 Zifan Wang , Akshay Joshi , Angkur Jyoti Dipanka Shaikeea , Vikram Susdhir Deshpande

We develop and demonstrate the first general computational tool for finite deformation static and dynamic dislocation mechanics. A finite element formulation of finite deformation (Mesoscale) Field Dislocation Mechanics theory is presented.…

Materials Science · Physics 2020-06-24 Rajat Arora , Xiaohan Zhang , Amit Acharya

A micromorphic computational homogenization framework has recently been developed to deal with materials showing long-range correlated interactions, i.e. displaying patterning modes. Typical examples of such materials are elastomeric…

Soft Condensed Matter · Physics 2024-06-21 S. Maraghechi , O. Rokoš , R. H. J. Peerlings , M. G. D. Geers , J. P. M. Hoefnagels

Computational homogenization is the gold standard for concurrent multi-scale simulations (e.g., FE2) in scale-bridging applications. Experimental and synthetic material microstructures are often represented by 3D image data. The…

Numerical Analysis · Mathematics 2022-09-07 Sanath Keshav , Felix Fritzen , Matthias Kabel

This paper reviews the current state-of-the-art in the simulation of the mechanical behavior of polycrystalline materials by means of computational homogenization. The key ingredients of this modelling strategy are presented in detail…

Materials Science · Physics 2018-11-22 J. Segurado , R. A. Lebensohn , J. LLorca

Classification of vertebral compression fractures (VCF) having osteoporotic or neoplastic origin is fundamental to the planning of treatment. We developed a fracture classification system by acquiring quantitative morphologic and bone…

Computer Vision and Pattern Recognition · Computer Science 2016-11-15 Yinong Wang , Jianhua Yao , Joseph E. Burns , Ronald M. Summers
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