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Quantification of intra-retinal boundaries in optical coherence tomography (OCT) is a crucial task for studying and diagnosing neurological and ocular diseases. Since manual segmentation of layers is usually a time consuming task and relay…

Computer Vision and Pattern Recognition · Computer Science 2015-02-17 Mahdi Salarian

Uncertainty estimation is critical for reliable medical image segmentation, particularly in retinal vessel analysis, where accurate predictions are essential for diagnostic applications. Deep Ensembles, where multiple networks are trained…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Jeremiah Fadugba , Petru Manescu , Bolanle Oladejo , Delmiro Fernandez-Reyes , Philipp Berens

Retinal fundus photography offers a non-invasive way to diagnose and monitor a variety of retinal diseases, but is prone to inherent quality glitches arising from systemic imperfections or operator/patient-related factors. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Vamsi Krishna Vasa , Peijie Qiu , Wenhui Zhu , Yujian Xiong , Oana Dumitrascu , Yalin Wang

Dynamic optical coherence tomography (DOCT) statistically analyzes fluctuations in time-sequential OCT signals, enabling label-free and three-dimensional visualization of intratissue and intracellular activities. Current DOCT methods, such…

Ophthalmic image segmentation serves as a critical foundation for ocular disease diagnosis. Although fully convolutional neural networks (CNNs) are commonly employed for segmentation, they are constrained by inductive biases and face…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Zunjie Xiao , Xiaoqing Zhang , Risa Higashita , Jiang Liu

Deep learning has emerged as a transformative approach for solving complex pattern recognition and object detection challenges. This paper focuses on the application of a novel detection framework based on the RT-DETR model for analyzing…

Computer Vision and Pattern Recognition · Computer Science 2025-01-29 Weijie He , Yuwei Zhang , Ting Xu , Tai An , Yingbin Liang , Bo Zhang

Diabetic retinopathy (DR) is a complication of diabetes, and one of the major causes of vision impairment in the global population. As the early-stage manifestation of DR is usually very mild and hard to detect, an accurate diagnosis via…

Computer Vision and Pattern Recognition · Computer Science 2022-12-14 Yuhan Zheng , Fuping Wu , Bartłomiej W. Papież

Objective: Optical coherence tomography (OCT) and its angiography (OCTA) have several advantages for the early detection and diagnosis of diabetic retinopathy (DR). However, automated, complete DR classification frameworks based on both OCT…

Image and Video Processing · Electrical Eng. & Systems 2020-09-28 Pengxiao Zang , Liqin Gao , Tristan T. Hormel , Jie Wang , Qisheng You , Thomas S. Hwang , Yali Jia

Purpose: Disease progression of retinal atrophy associated with AMD requires the accurate quantification of the retinal atrophy changes on longitudinal OCT studies. It is based on finding, comparing, and delineating subtle atrophy changes…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Adi Szeskin , Roei Yehuda , Or Shmueli , Jaime Levy , Leo Joskowicz

Optical Coherence Tomography (OCT) is one of the most important retinal imaging technique. However, involuntary motion artifacts still pose a major challenge in OCT imaging that compromises the quality of downstream analysis, such as…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Yiqian Wang , Alexandra Warter , Melina Cavichini , Varsha Alex , Dirk-Uwe G. Bartsch , William R. Freeman , Truong Q. Nguyen , Cheolhong An

Diabetic Retinopathy (DR) caused by diabetes occurs as a result of changes in the retinal vessels and causes visual impairment. Microaneurysms (MAs) are the early clinical signs of DR, whose timely diagnosis can help detecting DR in the…

Image and Video Processing · Electrical Eng. & Systems 2022-05-11 Elahe Sadat Kazemi Nasab , Ramin Almasi , Bijan Shoushtarian , Ehsan Golkar , Hossein Rabbani

Retinal neovascularization (RNV) is a vision threatening development in diabetic retinopathy (DR). Vision loss associated with RNV is preventable with timely intervention, making RNV clinical screening and monitoring a priority. Optical…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Jinyi Hao , Jie Wang , Liqin Gao , Tristan T. Hormel , Yukun Guo , An-Lun Wu , Christina J. Flaxel , Steven T. Bailey , Kotaro Tsuboi , Thomas S. Hwang , Yali Jia

The increasing prevalence of retinal diseases poses a significant challenge to the healthcare system, as the demand for ophthalmologists surpasses the available workforce. This imbalance creates a bottleneck in diagnosis and treatment,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-15 Jia-Hong Huang

In this paper we propose a novel deep learning-based algorithm for biomedical image segmentation which uses a sequential attention mechanism able to shift the focus of attention across the image in a selective way, allowing subareas which…

Computer Vision and Pattern Recognition · Computer Science 2019-09-30 Shohei Hayashi , Bisser Raytchev , Toru Tamaki , Kazufumi Kaneda

Self-supervised pre-training of deep learning models with contrastive learning is a widely used technique in image analysis. Current findings indicate a strong potential for contrastive pre-training on medical images. However, further…

Image and Video Processing · Electrical Eng. & Systems 2024-10-21 Daniel Wolf , Tristan Payer , Catharina Silvia Lisson , Christoph Gerhard Lisson , Meinrad Beer , Michael Götz , Timo Ropinski

A resolution enhancement technique for optical coherence tomography (OCT), based on Generative Adversarial Networks (GANs), was developed and investigated. GANs have been previously used for resolution enhancement of photography and optical…

Image and Video Processing · Electrical Eng. & Systems 2021-01-19 Kaicheng Liang , Xinyu Liu , Si Chen , Jun Xie , Wei Qing Lee , Linbo Liu , Hwee Kuan Lee

Small, imbalanced datasets and poor input image quality can lead to high false predictions rates with deep learning models. This paper introduces Class-Based Image Composition, an approach that allows us to reformulate training inputs…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Hlali Azzeddine , Majid Ben Yakhlef , Soulaiman El Hazzat

Optical coherence tomography (OCT) is a micrometer-scale, volumetric imaging modality that has become a clinical standard in ophthalmology. OCT instruments image by raster-scanning a focused light spot across the retina, acquiring…

Image and Video Processing · Electrical Eng. & Systems 2022-09-16 Stefan Ploner , Siyu Chen , Jungeun Won , Lennart Husvogt , Katharina Breininger , Julia Schottenhamml , James Fujimoto , Andreas Maier

In the real world, medical datasets often exhibit a long-tailed data distribution (i.e., a few classes occupy most of the data, while most classes have rarely few samples), which results in a challenging imbalance learning scenario. For…

Computer Vision and Pattern Recognition · Computer Science 2021-04-23 Lie Ju , Xin Wang , Lin Wang , Tongliang Liu , Xin Zhao , Tom Drummond , Dwarikanath Mahapatra , Zongyuan Ge

Optical tomographic cross-sectional images of biological samples were made possible by interferometric imaging techniques such as Optical Coherence Tomography (OCT). Owing to its unprecedented view of the sample, OCT has become a gold…

Medical Physics · Physics 2020-07-13 Pedro Mecê , Elena Gofas-Salas , Michel Paques , Kate Grieve , Serge Meimon