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The rise of large language models (LLMs) has transformed healthcare by offering clinical guidance, yet their direct deployment to patients poses safety risks due to limited domain expertise. To mitigate this, we propose repositioning LLMs…

Computation and Language · Computer Science 2025-10-14 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Prayag Tiwari , Xiang Wan , Feng Jiang , Benyou Wang

While large language models (LLMs) have shown promise in diagnostic dialogue, their capabilities for effective management reasoning - including disease progression, therapeutic response, and safe medication prescription - remain…

Digital health tools have the potential to significantly improve the delivery of healthcare services. However, their adoption remains comparatively limited due, in part, to challenges surrounding usability and trust. Large Language Models…

Computation and Language · Computer Science 2024-03-01 Fergus Imrie , Paulius Rauba , Mihaela van der Schaar

Clinical decision-making is inherently complex, often influenced by cognitive biases, incomplete information, and case ambiguity. Large Language Models (LLMs) have shown promise as tools for supporting clinical decision-making, yet their…

Machine Learning · Computer Science 2025-07-10 Burcu Sayin , Ipek Baris Schlicht , Ngoc Vo Hong , Sara Allievi , Jacopo Staiano , Pasquale Minervini , Andrea Passerini

Large Language Models (LLMs) have demonstrated impressive capabilities across various specialist domains and have been integrated into high-stakes areas such as medicine. However, as existing medical-related benchmarks rarely stress-test…

Computation and Language · Computer Science 2026-03-26 Lin Yang , Yuancheng Yang , Xu Wang , Changkun Liu , Haihua Yang

Large Language Model (LLM)-based Collective Intelligence (CI) presents a promising approach to overcoming the data wall and continuously boosting the capabilities of LLM agents. However, there is currently no dedicated arena for evolving…

Artificial Intelligence · Computer Science 2026-03-18 Peigen Liu , Rui Ding , Yuren Mao , Ziyan Jiang , Yuxiang Ye , Yunjun Gao , Ying Zhang , Renjie Sun , Longbin Lai , Zhengping Qian

Large Language Models (LLMs) are increasingly utilized for mental health support; however, current safety benchmarks often fail to detect the complex, longitudinal risks inherent in therapeutic dialogue. We introduce an evaluation framework…

Computation and Language · Computer Science 2026-03-06 Ian Steenstra , Paola Pedrelli , Weiyan Shi , Stacy Marsella , Timothy W. Bickmore

This paper presents an innovative large language model (LLM) agent framework for enhancing diagnostic accuracy in simulated clinical environments using the AgentClinic benchmark. The proposed automatic correction enables doctor agents to…

Artificial Intelligence · Computer Science 2024-10-15 Abhishek Dutta , Yen-Che Hsiao

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

With the increasing application of large language models (LLMs) in the medical domain, evaluating these models' performance using benchmark datasets has become crucial. This paper presents a comprehensive survey of various benchmark…

The healthcare industry is currently experiencing an unprecedented wave of cybersecurity attacks, impacting millions of individuals. With the discovery of thousands of vulnerabilities each month, there is a pressing need to drive the…

Computation and Language · Computer Science 2024-07-23 Rikhiya Ghosh , Oladimeji Farri , Hans-Martin von Stockhausen , Martin Schmitt , George Marica Vasile

Large language models (LLMs) have achieved significant success in interacting with human. However, recent studies have revealed that these models often suffer from hallucinations, leading to overly confident but incorrect judgments. This…

Computation and Language · Computer Science 2023-09-06 Yusheng Liao , Yutong Meng , Hongcheng Liu , Yanfeng Wang , Yu Wang

The implementation of Artificial Intelligence (AI) in the healthcare industry has garnered considerable attention, attributable to its prospective enhancement of clinical outcomes, expansion of access to superior healthcare, cost reduction,…

Computation and Language · Computer Science 2024-08-23 Arindam Sett , Somaye Hashemifar , Mrunal Yadav , Yogesh Pandit , Mohsen Hejrati

Though Large Vision-Language Models (LVLMs) are being actively explored in medicine, their ability to conduct complex real-world telemedicine consultations combining accurate diagnosis with professional dialogue remains underexplored. This…

Human-Computer Interaction · Computer Science 2025-11-12 Ivan Sviridov , Amina Miftakhova , Artemiy Tereshchenko , Galina Zubkova , Pavel Blinov , Andrey Savchenko

The development of large language models (LLMs) has brought unprecedented possibilities for artificial intelligence (AI) based medical diagnosis. However, the application perspective of LLMs in real diagnostic scenarios is still unclear…

Computation and Language · Computer Science 2024-05-21 Zhoujian Sun , Cheng Luo , Ziyi Liu , Zhengxing Huang

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

Demand for mental health support through AI chatbots is surging, though current systems present several limitations, like sycophancy or overvalidation, and reinforcement of maladaptive beliefs. A core obstacle to the creation of better…

Computation and Language · Computer Science 2025-12-08 José Pombal , Maya D'Eon , Nuno M. Guerreiro , Pedro Henrique Martins , António Farinhas , Ricardo Rei

Evaluating large language models (LLM) in clinical scenarios is crucial to assessing their potential clinical utility. Existing benchmarks rely heavily on static question-answering, which does not accurately depict the complex, sequential…

Human-Computer Interaction · Computer Science 2025-05-27 Samuel Schmidgall , Rojin Ziaei , Carl Harris , Eduardo Reis , Jeffrey Jopling , Michael Moor

The rapid advancements in large language models (LLMs) have opened up new opportunities for transforming patient engagement in healthcare through conversational AI. This paper presents an overview of the current landscape of LLMs in…

Artificial Intelligence · Computer Science 2024-11-27 Bo Wen , Raquel Norel , Julia Liu , Thaddeus Stappenbeck , Farhana Zulkernine , Huamin Chen

With the proliferation of Large Language Models (LLMs) in diverse domains, there is a particular need for unified evaluation standards in clinical medical scenarios, where models need to be examined very thoroughly. We present CliMedBench,…

Computation and Language · Computer Science 2024-10-07 Zetian Ouyang , Yishuai Qiu , Linlin Wang , Gerard de Melo , Ya Zhang , Yanfeng Wang , Liang He