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Coronary artery calcium (CAC) is a significant marker of atherosclerosis and cardiovascular events. In this work we present a system for the automatic quantification of calcium score in ECG-triggered non-contrast enhanced cardiac computed…

Computer Vision and Pattern Recognition · Computer Science 2017-10-10 G. Santini , D. Della Latta , N. Martini , G. Valvano , A. Gori , A. Ripoli , C. L. Susini , L. Landini , D. Chiappino

Every year, thousands of innocent people die due to heart attacks. Often undiagnosed heart attacks can hit people by surprise since many current medical plans don't cover the costs to require the searching of calcification on these scans.…

Image and Video Processing · Electrical Eng. & Systems 2022-09-23 Sanskriti Singh

Cardiovascular disease (CVD) is a common and strong threat to human beings, featuring high prevalence, disability and mortality. The amount of coronary artery calcification (CAC) is an effective factor for CVD risk evaluation.…

Image and Video Processing · Electrical Eng. & Systems 2019-07-29 Jiechao Ma , Rongguo Zhang

Coronary artery calcium (CAC) is highly predictive of cardiovascular events. While millions of chest CT scans are performed annually in the United States, CAC is not routinely quantified from scans done for non-cardiac purposes. A deep…

Coronary artery calcification (CAC) is a strong predictor of cardiovascular risk but remains underutilized in clinical routine thoracic imaging due to the need for dedicated imaging protocols and manual annotation. We present DeepCAC2, a…

Image and Video Processing · Electrical Eng. & Systems 2026-03-27 Leonard Nürnberg , Simon Bernatz , Borek Foldyna , Michael T. Lu , Andrey Fedorov , Hugo JWL Aerts

The Agatston score, which is the sum of the calcification in the four main coronary arteries, has been widely used in the diagnosis of coronary artery disease (CAD). However, many studies have emphasized the importance of the…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Doyoung Park , Jinsoo Kim , Qi Chang , Shuang Leng , Liang Zhong , Lohendran Baskaran

Coronary artery calcium (CAC) scoring is a key predictor of cardiovascular risk, but it relies on ECG-gated CT scans, restricting its use to specialized cardiac imaging settings. We introduce an automated framework for CAC detection and…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Mahmut S. Gokmen , Moneera N. Haque , Steve W. Leung , Caroline N. Leach , Seth Parker , Stephen B. Hobbs , Vincent L. Sorrell , W. Brent Seales , V. K. Cody Bumgardner

We propose a fully automated algorithm based on a deep learning framework enabling screening of a coronary computed tomography angiography (CCTA) examination for confident detection of the presence or absence of coronary artery…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Sema Candemir , Richard D. White , Mutlu Demirer , Vikash Gupta , Matthew T. Bigelow , Luciano M. Prevedello , Barbaros S. Erdal

Cardiovascular disease causes high rates of mortality worldwide. Coronary artery calcium (CAC) scoring is a powerful tool to stratify the risk of atherosclerotic cardiovascular disease. Current scoring practices require time-intensive…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Lachlan Nguyen , Aidan Cousins , Arcot Sowmya , Hugh Dixson , Sonit Singh

Coronary artery calcium (CAC) burden quantified in low-dose chest CT is a predictor of cardiovascular events. We propose an automatic method for CAC quantification, circumventing intermediate segmentation of CAC. The method determines a…

Computer Vision and Pattern Recognition · Computer Science 2017-12-11 Bob D. de Vos , Nikolas Lessmann , Pim A. de Jong , Max A. Viergever , Ivana Isgum

Vessel stenosis is a major risk factor in cardiovascular diseases (CVD). To analyze the degree of vessel stenosis for supporting the treatment management, extraction of coronary artery area from Computed Tomographic Angiography (CTA) is…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Yo-Chuan Chen , Yi-Chen Lin , Ching-Ping Wang , Chia-Yen Lee , Wen-Jeng Lee , Tzung-Dau Wang , Chung-Ming Chen

Assessing coronary artery plaque segments in coronary CT angiography scans is an important task to improve patient management and clinical outcomes, as it can help to decide whether invasive investigation and treatment are necessary. In…

Heavy smokers undergoing screening with low-dose chest CT are affected by cardiovascular disease as much as by lung cancer. Low-dose chest CT scans acquired in screening enable quantification of atherosclerotic calcifications and thus…

Computer Vision and Pattern Recognition · Computer Science 2018-02-06 Nikolas Lessmann , Bram van Ginneken , Majd Zreik , Pim A. de Jong , Bob D. de Vos , Max A. Viergever , Ivana Išgum

Various types of atherosclerotic plaque and varying grades of stenosis could lead to different management of patients with coronary artery disease. Therefore, it is crucial to detect and classify the type of coronary artery plaque, as well…

Computer Vision and Pattern Recognition · Computer Science 2018-12-11 Majd Zreik , Robbert W. van Hamersvelt , Jelmer M. Wolterink , Tim Leiner , Max A. Viergever , Ivana Isgum

We propose a deep learning-based automatic coronary artery tree centerline tracker (AuCoTrack) extending the vessel tracker by Wolterink (arXiv:1810.03143). A dual pathway Convolutional Neural Network (CNN) operating on multi-scale 3D…

Image and Video Processing · Electrical Eng. & Systems 2023-11-27 Zohaib Salahuddin , Matthias Lenga , Hannes Nickisch

Analysing coronary artery plaque segments with respect to their functional significance and therefore their influence to patient management in a non-invasive setup is an important subject of current research. In this work we compare and…

Image and Video Processing · Electrical Eng. & Systems 2019-12-16 Felix Denzinger , Michael Wels , Katharina Breininger , Anika Reidelshöfer , Joachim Eckert , Michael Sühling , Axel Schmermund , Andreas Maier

Coronary artery calcium (CAC) is biomarker of advanced subclinical coronary artery disease and predicts myocardial infarction and death prior to age 60 years. The slice-wise manual delineation has been regarded as the gold standard of…

Computer Vision and Pattern Recognition · Computer Science 2018-11-13 Yuankai Huo , James G. Terry , Jiachen Wang , Vishwesh Nath , Camilo Bermudez , Shunxing Bao , Prasanna Parvathaneni , J. Jeffery Carr , Bennett A. Landman

Coronary angiography is considered to be a safe tool for the evaluation of coronary artery disease and perform in approximately 12 million patients each year worldwide. [1] In most cases, angiograms are manually analyzed by a cardiologist.…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Stanislav Filippov , Arsenii Moiseev , Andronenko Andrey

Carotid arteries vulnerable plaques are a crucial factor in the screening of atherosclerosis by ultrasound technique. However, the plaques are contaminated by various noises such as artifact, speckle noise, and manual segmentation may be…

Image and Video Processing · Electrical Eng. & Systems 2022-04-19 Yanchao Yuan , Cancheng Li , Lu Xu , Ke Zhang , Yang Hua , Jicong Zhang

Coronary CT angiography (CCTA) has established its role as a non-invasive modality for the diagnosis of coronary artery disease (CAD). The CAD-Reporting and Data System (CAD-RADS) has been developed to standardize communication and aid in…

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