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Metastases increase the risk of fracture when affecting the femur. Consequently, clinicians need to know if the patients femur can withstand the stress of daily activities. The current tools used in clinics are not sufficiently precise. A…

Finite element analysis is one of the most used tool for studying femoral neck fracture. Nerveless, consensus concerning either the choice of material characteristics, damage law and /or geometric models (linear on nonlinear) still remains…

The incidence of vertebral fragility fracture is increased by the presence of preexisting pathologies such as metastatic disease. Computational tools could support the fracture prediction and consequently the decision of the best medical…

Computational Engineering, Finance, and Science · Computer Science 2024-02-16 Chiara Garavelli , Alessandra Aldieri , Marco Palanca , Enrico Dall'Ara , Marco Viceconti

Lower limb amputees often suffer skin and tissue problems from using their prosthesis which is a challenging biomechanical problem. The finite element method (FEM) has previously been applied to analyse internal mechanical conditions of the…

Medical Physics · Physics 2019-08-02 Sara Kallin , Asim Rashid , Kent Salomonsson , Peter Hansbo

Osteolytic metastases located in the vertebrae reduce strength and enhance the risk of vertebral fractures. This risk can be predicted by means of validated finite element models, but their reproducibility needs to be assessed. For that…

Tissues and Organs · Quantitative Biology 2025-03-24 W. Lokbani , V. Allard , T. Broussolle , CY. Barrey , C. B. Confavreux , K. Bruyere , JP. Roux , F. Bermond , H. Follet , D. Mitton

Vertebral fractures prediction in clinics lacks of accuracy. The most used scores have limitations in distinguishing between subjects at risk or not. Finite element (FE) models generated from computed tomography (CT) of these patients may…

Computational Engineering, Finance, and Science · Computer Science 2024-02-16 Chiara Garavelli , Alessandra Aldieri , Marco Palanca , Luca Patruno , Marco Viceconti

We consider mixed finite element methods for linear elasticity where the symmetry of the stress tensor is weakly enforced. Both an a priori and a posteriori error analysis are given for several known families of methods that are uniformly…

Numerical Analysis · Mathematics 2023-02-01 Philip L. Lederer , Rolf Stenberg

Understanding the mechanical behaviour of bones up to failure is necesary for diagnosis and prevention of accident and trauma. As far as we know, no authors have yet studied the tensile behaviour of compact bone including failure under…

Classical Physics · Physics 2007-05-23 Martine Pithioux , D. Subit , P. Chabrand

The predictive capabilities of the finite element approach were assessed by comparing simulation outputs with experimental results, including load-displacement trends, damage initiation points, and delamination evolution. This comparison…

Computational Physics · Physics 2025-05-27 Constantinos Rouvalis , Vassilis Kostopoulos , Spyridon Psarras

Estimating heterogeneous treatment effects with machine learning has attracted substantial attention in both academic research and industrial practice. However, the two communities often evaluate models under markedly different conditions.…

Machine Learning · Computer Science 2026-05-26 George Panagopoulos

Bone is a multiscale heterogeneous materiel of which principal function is to support the body structure and to resist mechanical loading and fractures. Bone strength does not depend only on the quantity and quality of bone which is…

Tissues and Organs · Quantitative Biology 2011-07-07 Abdelwahed Barkaoui , Awad Bettamer , Ridha Hambli

The combination of Finite Element Method (FEM) simulation and experimental photo-elasticity provides both qualitative and quantitative information about the stress field in a polymer composite and particularly along the fibre-matrix…

Materials Science · Physics 2007-05-23 H. Matthias Deuschle , Falk K. Wittel , Henry Gerhard , Gerhard Busse , Bernd-H. Kroeplin

In general, there is a mismatch between a finite element model {(FEM)} of a structure and its real behaviour. In aeronautics, this mismatch must be small because {FEM}s are a fundamental part of the development of an aircraft and of…

Computational Engineering, Finance, and Science · Computer Science 2026-04-20 Gabriele Dessena , Alessandro Pontillo , Dmitry I. Ignatyev , James F. Whidborne , Luca Zanotti Fragonara

Repetitive loading of bone is associated with microdamage accumulation and material property degradation that may ultimately result in fatigue fracture. Our previous work used continuum damage mechanics (CDM)-based finite element (FE)…

Medical Physics · Physics 2025-04-23 Reza Kakavand , Jonah M. Dimnik , Ifaz T. Haider , W. Brent Edwards

The outcome of vertebroplasty is hard to predict due to its dependence on complex factors like bone cement and marrow rheologies. Cement leakage could occur if the procedure is done incorrectly, potentially causing adverse complications. A…

A preliminary iterative 3D meso-scale structural model of the femur was developed, in which bar and shell elements were used to represent trabecular and cortical bone respectively. The cross-sectional areas of the bar elements and the…

Medical Physics · Physics 2012-03-01 Andrew T. M. Phillips

The study of pathological cardiac conditions such as arrhythmias, a major cause of mortality in heart failure, is becoming increasingly informed by computational simulation, numerically modelling the governing equations. This can provide…

Computational Engineering, Finance, and Science · Computer Science 2014-06-09 Nathan Kirk , Alan Benson , Christopher Goodyer , Matthew Hubbard

The integration of artificial intelligence into clinical workflows requires reliable and robust models. Repeatability is a key attribute of model robustness. Repeatable models output predictions with low variation during independent tests…

Although the socket is critical in a prosthetic system for a person with limb amputation, the methods of its design are largely artisanal. A roadblock for a repeatable and quantitative socket design process is the lack of predictive and…

Medical Physics · Physics 2016-03-01 David Moinina Sengeh , Kevin Mattheus Moerman , Arthur Petron , Hugh Herr

We present useful connections between the finite difference and the finite element methods for a model boundary value problem. We start from the observation that, in the finite element context, the interpolant of the solution in one…

Numerical Analysis · Mathematics 2021-07-16 Cristina Bacuta , Constantin Bacuta
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